\/p>","gtin12":"039442030146","image":["https:\/\/siteimgs.com\/10017\/item\/cuts-42packs-1_1746217986-0.jpg","https:\/\/siteimgs.com\/10017\/item\/cutspills-suppfacts_1746218053-0.jpg","https:\/\/siteimgs.com\/10017\/item\/cuts-pillexplainer_1746218056-0.jpg"],"brand":"ANIMAL Pak","url":"https:\/\/www.dpsnutrition.net\/i\/5917\/universal-animal-cuts-42-packs.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"43.95","url":"https:\/\/www.dpsnutrition.net\/i\/5917\/universal-animal-cuts-42-packs.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Animal Cuts Powder Blue Ice Pop - 42 Servings","sku":"UV447","description":"
Animal Cuts Powder is the powder version of our fat burning and shredding supplement with 17 fat burning ingredients to boost your metabolism, suppress appetite, help define muscles, support brain health, and support with weight management. This an all-in-one thermogenic fat burner is formulated for men and women who want to naturally shed excess fat and water weight.<\/p>\r\n
Animal Cuts isn’t just a fat burner, lipolytic, diuretic, or metabolic; it’s all four in a delicious tasting powder containing research-backed ingredients that assists in burning fat for both men and women. An award-winning supplement, mix Animal Cuts Powder with your beverage of choice for a potent thermogenic fat burner that can help boost the body’s natural ability to burn stored body fat while promoting lean mass. <\/p>\r\n<\/div>\r\n<\/div>\r\n
Our comprehensive formula gives your metabolism a boost with two key forms of L-Carnitine and Tyrosine, Choline, Caffeine, Green Tea Extract. Unlike other fat-burning supplements, Animal Cuts contains potassium-sparing herbs which help preserve muscular fullness, so your muscles won’t lose their pump and size.<\/p>\r\n
The Animal Cuts muscle shredding supplement is formulated with research-backed ingredients in eight complexes designed to help men and women lose weight without sacrificing their muscle definition: (1) thermogenic complex; (2) metabolic complex; (3) nootropic complex; (4) cortisol-inhibiting complex; (5) thyroid complex; (6) diuretic complex; (7) appetite suppression complex; and (8) our special bioavailability complex.<\/p>\r\n
<\/p>\r\n
<\/p>","gtin12":"039442032928","image":["https:\/\/siteimgs.com\/10017\/item\/cutspowder-235g-blueicepo_1746210251-0.jpg","https:\/\/siteimgs.com\/10017\/item\/cutspowder-ingredients_1746210258-0.jpg"],"brand":"ANIMAL Pak","url":"https:\/\/www.dpsnutrition.net\/i\/30797\/universal-animal-cuts-powder-blue-ice-pop-42.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"43.95","url":"https:\/\/www.dpsnutrition.net\/i\/30797\/universal-animal-cuts-powder-blue-ice-pop-42.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Animal Cuts Powder Orange Mango - 42 Servings","sku":"UV448","description":"
Animal Cuts Powder is the powder version of our fat burning and shredding supplement with 17 fat burning ingredients to boost your metabolism, suppress appetite, help define muscles, support brain health, and support with weight management. This an all-in-one thermogenic fat burner is formulated for men and women who want to naturally shed excess fat and water weight.<\/p>\r\n
Animal Cuts isn’t just a fat burner, lipolytic, diuretic, or metabolic; it’s all four in a delicious tasting powder containing research-backed ingredients that assists in burning fat for both men and women. An award-winning supplement, mix Animal Cuts Powder with your beverage of choice for a potent thermogenic fat burner that can help boost the body’s natural ability to burn stored body fat while promoting lean mass. <\/p>\r\n<\/div>\r\n<\/div>\r\n
Our comprehensive formula gives your metabolism a boost with two key forms of L-Carnitine and Tyrosine, Choline, Caffeine, Green Tea Extract. Unlike other fat-burning supplements, Animal Cuts contains potassium-sparing herbs which help preserve muscular fullness, so your muscles won’t lose their pump and size.<\/p>\r\n
The Animal Cuts muscle shredding supplement is formulated with research-backed ingredients in eight complexes designed to help men and women lose weight without sacrificing their muscle definition: (1) thermogenic complex; (2) metabolic complex; (3) nootropic complex; (4) cortisol-inhibiting complex; (5) thyroid complex; (6) diuretic complex; (7) appetite suppression complex; and (8) our special bioavailability complex.<\/p>\r\n
<\/p>\r\n
<\/p>","gtin12":"039442032935","image":["https:\/\/siteimgs.com\/10017\/item\/cutspowder-orangemango-26_1746210434-0.jpg","https:\/\/siteimgs.com\/10017\/item\/cutspowder-ingredients_1746210437-0.jpg"],"brand":"ANIMAL Pak","url":"https:\/\/www.dpsnutrition.net\/i\/30819\/animal-cuts-powder-orange-mango-42-servings.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"43.95","url":"https:\/\/www.dpsnutrition.net\/i\/30819\/animal-cuts-powder-orange-mango-42-servings.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Animal Cuts Powder Rainbow Candy - 42 Servings","sku":"UV498","description":"
Animal Cuts Powder is the powder version of our fat burning and shredding supplement with 17 fat burning ingredients to boost your metabolism, suppress appetite, help define muscles, support brain health, and support with weight management. This an all-in-one thermogenic fat burner is formulated for men and women who want to naturally shed excess fat and water weight.<\/p>\r\n
Animal Cuts isn’t just a fat burner, lipolytic, diuretic, or metabolic; it’s all four in a delicious tasting powder containing research-backed ingredients that assists in burning fat for both men and women. An award-winning supplement, mix Animal Cuts Powder with your beverage of choice for a potent thermogenic fat burner that can help boost the body’s natural ability to burn stored body fat while promoting lean mass. <\/p>\r\n<\/div>\r\n<\/div>\r\n
Our comprehensive formula gives your metabolism a boost with two key forms of L-Carnitine and Tyrosine, Choline, Caffeine, Green Tea Extract. Unlike other fat-burning supplements, Animal Cuts contains potassium-sparing herbs which help preserve muscular fullness, so your muscles won’t lose their pump and size.<\/p>\r\n
The Animal Cuts muscle shredding supplement is formulated with research-backed ingredients in eight complexes designed to help men and women lose weight without sacrificing their muscle definition: (1) thermogenic complex; (2) metabolic complex; (3) nootropic complex; (4) cortisol-inhibiting complex; (5) thyroid complex; (6) diuretic complex; (7) appetite suppression complex; and (8) our special bioavailability complex.<\/p>\r\n
<\/p>\r\n
<\/p>","gtin12":"039442016966","image":["https:\/\/siteimgs.com\/10017\/item\/cuts-rainbow_1746217526-0.jpg","https:\/\/siteimgs.com\/10017\/item\/cutspowder-ingredients_1746210913-0.jpg"],"brand":"ANIMAL Pak","url":"https:\/\/www.dpsnutrition.net\/i\/35342\/animal-cuts-powder-rainbow-candy-42-servings.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"43.95","url":"https:\/\/www.dpsnutrition.net\/i\/35342\/animal-cuts-powder-rainbow-candy-42-servings.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Animal Cuts Powder Strawberry Watermelon - 42 Servings","sku":"UV455","description":"
Animal Cuts Powder is the powder version of our fat burning and shredding supplement with 17 fat burning ingredients to boost your metabolism, suppress appetite, help define muscles, support brain health, and support with weight management. This an all-in-one thermogenic fat burner is formulated for men and women who want to naturally shed excess fat and water weight.<\/p>\r\n
Animal Cuts isn’t just a fat burner, lipolytic, diuretic, or metabolic; it’s all four in a delicious tasting powder containing research-backed ingredients that assists in burning fat for both men and women. An award-winning supplement, mix Animal Cuts Powder with your beverage of choice for a potent thermogenic fat burner that can help boost the body’s natural ability to burn stored body fat while promoting lean mass. <\/p>\r\n<\/div>\r\n<\/div>\r\n
Our comprehensive formula gives your metabolism a boost with two key forms of L-Carnitine and Tyrosine, Choline, Caffeine, Green Tea Extract. Unlike other fat-burning supplements, Animal Cuts contains potassium-sparing herbs which help preserve muscular fullness, so your muscles won’t lose their pump and size.<\/p>\r\n
The Animal Cuts muscle shredding supplement is formulated with research-backed ingredients in eight complexes designed to help men and women lose weight without sacrificing their muscle definition: (1) thermogenic complex; (2) metabolic complex; (3) nootropic complex; (4) cortisol-inhibiting complex; (5) thyroid complex; (6) diuretic complex; (7) appetite suppression complex; and (8) our special bioavailability complex.<\/p>\r\n
<\/p>\r\n
<\/p>","gtin12":"039442032942","image":["https:\/\/siteimgs.com\/10017\/item\/cutspowder-strawberrywate_1746210469-0.jpg","https:\/\/siteimgs.com\/10017\/item\/cutspowder-ingredients_1746210472-0.jpg"],"brand":"ANIMAL Pak","url":"https:\/\/www.dpsnutrition.net\/i\/31628\/animal-cuts-powder-strawberry-watermelon-42.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"43.95","url":"https:\/\/www.dpsnutrition.net\/i\/31628\/animal-cuts-powder-strawberry-watermelon-42.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Apollon Nutrition Chaos V4 - 120 Capsules","sku":"APN99","description":"
MELT YOUR FAT RAPIDLY WITH CHAOS!<\/p>\r\n
APOLLON NUTRITION CHAOS – HARDCORE FAT BURNER† There are cheap caffeine pills with under-dosed ingredients calling themselves fat burners and then there is Chaos. This ultra-potent formula was not designed to fit in one capsule because it contains powerful ingredients in their correct doses. After the first serving of Chaos you’ll understand why it’s becoming one of the most popular fat-burners on the market today.†<\/p>\r\n
<\/p>\r\n
<\/p>\r\n
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.<\/p>","gtin12":"850042072226","image":["https:\/\/siteimgs.com\/10017\/item\/chaosv4-btl_1671206021-0.jpg","https:\/\/siteimgs.com\/10017\/item\/chaos-hardcore-fat-burner_1739894577-0.jpg"],"brand":"Apollon Nutrition","url":"https:\/\/www.dpsnutrition.net\/i\/32691\/apollon-nutrition-chaos-v4-120-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"47.96","url":"https:\/\/www.dpsnutrition.net\/i\/32691\/apollon-nutrition-chaos-v4-120-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Apollon Nutrition Chaos V4 - 240 Capsules (2 x 120 Capsule Bottles) TWINPACK","sku":"APN299","description":"
MELT YOUR FAT RAPIDLY WITH CHAOS!<\/p> \r\n
APOLLON NUTRITION CHAOS – HARDCORE FAT BURNER† There are cheap caffeine pills with under-dosed ingredients calling themselves fat burners and then there is Chaos. This ultra-potent formula was not designed to fit in one capsule because it contains powerful ingredients in their correct doses. After the first serving of Chaos you’ll understand why it’s becoming one of the most popular fat-burners on the market today.†<\/p>\r\n
<\/p>\r\n
<\/p>\r\n
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.<\/p>","gtin12":"850042072226","image":["https:\/\/siteimgs.com\/10017\/item\/chaos-2_1739894306-0.jpg","https:\/\/siteimgs.com\/10017\/item\/chaos-hardcore-fat-burner_1739894481-0.jpg"],"brand":"Apollon Nutrition","url":"https:\/\/www.dpsnutrition.net\/i\/34939\/apollon-nutrition-chaos-v4-120-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"87.99","url":"https:\/\/www.dpsnutrition.net\/i\/34939\/apollon-nutrition-chaos-v4-120-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Apollon Nutrition Molotov V3 - Non-stim Fat Burner & Thermogenic - 120 Capsules","sku":"APN58","description":"","gtin12":"850862007859","image":["https:\/\/siteimgs.com\/10017\/item\/molotov_1725916122-0.jpg"],"brand":"Apollon Nutrition","url":"https:\/\/www.dpsnutrition.net\/i\/31576\/apollon-nutrition-molotov-v3-non-stim-fat-burner.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"47.99","url":"https:\/\/www.dpsnutrition.net\/i\/31576\/apollon-nutrition-molotov-v3-non-stim-fat-burner.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Axe & Sledge Double Time - 60 Capsules","sku":"AXS33","description":"
Lose fat and look good naked!<\/p>
When you need to kick your metabolism into overtime, reach for a bottle of double time from axe & sledge! Double time is a fat-burning thermogenic that's formulated for everyone. As the name suggests, double time is designed to be taken first thing in the morning and in the early afternoon to keep you energized, focused, and burning fat.<\/p>
With 10 efficaciously dosed ingredients, double time is one of the most comprehensive fat burners on the market! Not to mention, double time uses three patented ingredients to maximize your results, including:<\/p>
Double time was specifically formulated to combat the common side effects that users experience from dieting, such as fatigue, decreased performance, difficulty concentrating, hunger, and reduced metabolic rate.<\/p>
Taking double time alongside a well-structured diet and training regimen will result in:<\/p>
Double time won\u2019t do the work for you, but it will help you reach your physique goals much faster. When you're ready to lose the fat for good, grab a bottle of double time and get ready to work!<\/p>
N-acetyl l-tyrosine (nalt) is an acetylated form of tyrosine, a non-essential amino acid that can be synthesized by the body using phenylalanine.<\/p>
Tyrosine is a direct precursor to three important neurotransmitters:<\/p>
These neurotransmitters are crucial components of your sympathetic nervous system, which is activated during exercise. Excessive physical and\/or mental stress can significantly deplete your neurotransmitters. So restoring their levels primes your body for performance and fat loss.<\/p>
Supplementing with nalt may:<\/p>
Caffeine anhydrous is the most widely used and researched ingredient in sports nutrition. It's been proven time and again to be effective and safe. Caffeine is a powerful stimulant that quickly raises energy levels by inhibiting adenosine and phosphodiesterase.<\/p>
Caffeine anhydrous may:<\/p>
Turmeric root powder is rich in curcumin, a bioactive polyphenol that's associated with numerous health benefits. Curcumin is a powerful antioxidant, anti-inflammatory, neuroprotective, cardioprotective, anticancer, antidepressant, and antiarthritic. However, curcumin is also beneficial for weight loss.<\/p>
Some evidence suggests that curcumin is capable of increasing your basal metabolic rate (bmr), resulting in greater caloric expenditure. The more calories you burn throughout the day, the easier it is to lose fat. It's important to note that curucmin, by itself, isn't absorbed well in the small intestine.<\/p>
This is one of the main reasons why we added bioperine\u00ae, a black pepper extract, to counteract this potential issue. Bioperine\u00ae significantly increases the absorption and effectiveness of curcumin.<\/p>
Green tea extract has an abundance of health benefits due to its high antioxidant content. The antioxidant that's mainly attributed to green tea extract weight-loss promoting effects is epigallocatechin gallate (egcg). Furthermore, green tea extract contains small amounts of caffeine.<\/p>
The combination of egcg and caffeine allow green tea extract to increase energy levels and thermogenesis. Simply put, green tea extract boosts your metabolism, leading to a greater amount of calories burned! Not to mention, egcg\u2019s help lowers blood sugar levels and improve insulin sensitivity. Beyond weight loss, green tea extract is a powerful antioxidant and promotes skin, liver, brain, and heart health.<\/p>
Dandelion extract (taraxcrum officinale) is also considered to be a powerful natural diuretic. In fact, it's been used as a diuretic for centuries in both ayurvedic and traditional chinese medicine. Since dandelion extract is also rich in vitamins and minerals, it can help rid the body of excess water, without depleting electrolyte levels. Dandelion extract primarily carries out its effects by increasing urinary frequency. Moreover, dandelion has antioxidant, anti-inflammatory, and cardioprotective properties.<\/p>
White willow bark extract, also known as salix alba, is commonly used to reduce fevers, inflammation, and pain. The primary bioactive compound in willow bark that's attributed to its effects is called salicin. The main benefit of willow bark is pain relief, but it\u2019s also commonly used in weight loss supplements to improve the effectiveness of other ingredients.<\/p>
Choline bitartrate supplies the body with choline, an essential nutrient that's responsible for a number of physiological processes. In regards to exercise, choline is most notably used for the production of acetylcholine. Acetylcholine is a neurotransmitter that's essential for carrying out muscle contractions. Choline bitartrate is composed of choline bound to two tartaric acids, which improves absorption, bioavailability, and effectiveness.<\/p>
Choline bitartrate may:<\/p>
Capsimax\u2122 is a concentrated extract of capsaicinoids derived from cayenne peppers. Capsaicinoids are the naturally occurring compounds that give cayenne peppers their spice. However, these capsaicinoids, specifically capsaicin, dihydrocapsaicin, and nordihydrocapsaicin, are also attributed to their weight-loss properties.<\/p>
Unfortunately, generic cayenne pepper extracts can lead to some negative effects, such as an upset stomach, which is why we chose capsimax\u2122 for double time.<\/p>
Using omnibead beadlet technology, omniactive health technologies was able to harness the benefits of capsaicinoids, without the negative effects associated with cayenne pepper consumption. Through various mechanisms of action, capsimax\u2122 is able to increase lipolysis and fat oxidation, while reducing appetite.<\/p>
Advantra z\u00ae is a high-quality bitter orange extract, also known as citrus aurantium, that's self-affirmed gras (generally recognized as safe) and standardized to contain at least 30% synephrine. Synephrine is an alkaloid that's attributed to bitter orange extract\u2019s numerous benefits.<\/p>
Due to its rich content of synephrine, advantra z\u00ae delivers powerful energy, boosts thermogenesis, and suppresses appetite. Advantra z\u00ae is one of the most effective weight loss ingredients on the market, which is why we use it in double time. Advantra z\u00ae is a branded ingredient developed by innophos.<\/p>
Bioperine\u00ae is a patented black pepper that's standardized to contain at least 95% piperine, which is the main bioactive constituent. Bioperine\u00ae improves the effectiveness of double time by enhancing the bioavailability and absorption of each ingredient.<\/p>
Since some dietary ingredients, such as curcumin, aren\u2019t readily absorbed by the small intestine, we included bioperine\u00ae to help you get the most out of double time. Bioperine\u00ae was developed by sabinsa corporation.<\/p>
Bioperine\u00ae may:<\/p>
Take 2 capsules with 8-10 oz. Of water before your first meal of the day. Take an additional capsule 6-8 hours later as needed.<\/p>
Warning: consult with a physician prior to use if you have a medical condition. Don\u2019t use if pregnant or lactating. Keep out of reach of children. Keep container tightly closed in a cool, dry and dark place.<\/p>
These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.<\/p>","gtin12":"753577015129","image":["https:\/\/siteimgs.com\/10017\/item\/doubletime-5000x_1614787426-0.jpg"],"brand":"Axe & Sledge","url":"https:\/\/www.dpsnutrition.net\/i\/30689\/axe-sledge-double-time-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.99","url":"https:\/\/www.dpsnutrition.net\/i\/30689\/axe-sledge-double-time-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"Axis Labs Synthalean XD - 60 Capsules","sku":"AX079","description":"
Introducing High-Potency SYNTHALEAN XD, Now with Dynamine!<\/p>
New and Improved? Yes! Synthalean XD now combines much of the power of Synthalean but now with Dynamine. Teacrine was a powerful component of the original Synthalean, but now Dynamine combined with Teacrine and Caffeine create a powerful stimulant combination that lasts all day without being uncomfortably strong. Additionally, Synthalean XD comes in a two (2) capsule serving, providing you with half the strength if it's not the right time for a full serving.<\/p>
Seriously, you can have it all with Axis Labs\u2019 innovative high-potency thermogenic, SYNTHALEAN XD. An advanced fat-loss technology, SYNTHALEAN XD is a body fat burning, weight loss jackhammer. The cutting edge burn supplement works synergistically to optimize your fat-burn naturally without energy crashes, jitters, and other unwelcome side effects. This unique blend of branded ingredients, backed by human research clinical studies \u2026 comes together in a ground breaking, FAT INCINERATING, ENERGY GENERATING, FOCUS INDUCING CAPSULE.<\/p>
Body Fat burning comes from tipping the formula of physical activity to calorie intake. Ultimately, burning more calories than you consume combined with your resting metabolic rate (the amount of calories you expend without exercise) results in rapid and managed weight loss that has lasting results.<\/p>
Over caffeinated products by themselves are not the answer. Too much caffeine causes jitters, the dreadful crash, and grogginess.<\/p>
SYNTHALEAN: is formulated with multiple natural stimulants that peaks at different times and gradually subsides so there\u2019s no crash, jitters, or grogginess. SYNTHALEAN: is strong. As a thermogenic, it boosts temperature and energy to literally melt fat. You can feel this fast-acting body fat burning supplement working. SYNTHALEAN: this potent fat-incinerating product works by combining the latest science has to offer to provide you with the greatest fat burning capacity.<\/p>
In development for over two years in countless versions, SYNTHALEAN XD improved alongside the ingredients and science. Our high-tech formulators used the best ingredients and scientifically formulated the synergy among the ingredients to create an incredible supplement to take for weight loss. Not only are we bringing you new, patented ingredients, but more importantly, ingredients that are safe and have been researched to work alone and together with some of the formulations other ingredients to allow for ultimate synergy and weight loss.<\/p>
Recently, a landmark clinical trial was conducted at a major Division I university to investigate Dynamine's potential pharmacokinetic interaction with caffeine and Teacrine. Remarkably, researchers discovered that Dynamine extended caffeine\u2019s half-life and increased its area under the curve approximately two-fold. The reverse was not true (i.e. caffeine did not alter Dynamine's pharmacokinetics). In addition, researchers also discovered that co-administration of Teacrine and Dynamine increased the half-life of caffeine approximately three-fold.<\/p>
SYNTHALEAN XD is a scientifically developed formulation designed to:<\/p>
It is super strength condensed into one or two capsules! Without the Unwanted Effects Everything You Need, Nothing You Don\u2019t<\/p>
Harsh stimulants and aggressive burn supplements are not required to stimulate body fat reduction. In fact, aggressive and high amounts of caffeine can unnecessarily tax your nervous system and leave you restless at night. Disturbances to sleep, mood, and focus are the opposite of what you need to optimize your body composition. No more peaks and valleys. Ups and downs. Jitters and shivers. Being alert one minute and then crashing and anxious the next.<\/p>
SYNTHALEAN XD is precision formulated to provide boundless energy that feels good and tapers gently to avoid crashing energy. With SYNTHALEAN XD, you can stay alert and awake, as well as burn fat all day long.<\/p>
Axis Labs has been providing unique and premium formulations for over 10 years. The makers of HYPERTEST XD, Myodex and HemodrauliX, Axis Labs is committed to the best ingredients in efficacious doses to provide superior quality of products for all your body fat burning supplementation needs.<\/p>
We have the willpower. We have the innovation. We have the next generation secret that will allow you to break through and break free of excess fat.<\/p>
Enough is enough: It\u2019s time for you to look in that mirror and be happy with what you see. No need to keep feeling \u201cover stimmed\u201d without results. Be alert, in the zone, and at your best. Lose the ceaseless hunger pangs. Metabolism optimized. Brain optimized. The best fat incinerator in the world period\u2026 in one capsule. Evolve past stimulants to the new and improved YOU with this revolutionary weight reduction supplement.<\/p>
Are you ready to change? Are you ready to look into the mirror and smile from ear to ear, filled with enthusiasm because of the battles and barriers you have overcome?<\/p>
If so, get SYNTHALEAN XD!<\/p>
Dynamine: Dynamine\u00ae is methylliberine, a purine alkaloid found in the kucha tea leaf. Its molecular structure is similar to theacrine (aka TeaCrine\u00ae) and is believed to behave in similar ways in the body. Like theacrine, methylliberine may amplify feelings of energy, mood and focus by activating dopamine receptors and other key neurotransmitters, inhibiting adenosine receptors, all without elevating heart rate or blood pressure.<\/p>
TeaCrine: Teacrine is a brand new patented ingredient (similar to caffeine) that provides clean, body fat burning energy without the crash or habituation. Teacrine has been shown to improve mood, energy, and focus all while helping you optimize and improve your energy expenditure. Properties include:<\/p>
L-TeaCrine: L-Theanine, when combined with Teacrine and caffeine, provides the ultimate combination. L Theanine will reduce the excitability caused by caffeine while retaining the focus and attention span benefits that caffeine provides. Not only does L-Theanine prevent from the \u201cover-stimmed\u201d conundrum, but research also suggests it can improve mental recovery after physical stress (i.e. working out) and cognitive performance. L-theanine, a branched-chain amino acid found in green tea leaves, has been linked to reducing mental stress and has relaxing effects without causing drowsiness (Juneja 1999).<\/p>
Caffeine: Caffeine, in combination with the aforementioned ingredients will really spice up this formula. Several studies have shown significant increases in intramuscular fat oxidation during exercise when caffeine was given prior to the bout. Caffeine combined with L-theanine and Teacrine create the ultimate trio of a balanced stimulant, fat oxidation, and clean energy feel.<\/p>
N-Acetyl Tyrosine: Tyrosine is the precursor of the catecholamine (CA), neurotransmitters dopamine (DA), norepinephrine (NE), and epinephrine. Tyrosine may preserve arousal during exercise and allow for prolonged and enhanced performance. While caffeine appears to improve focus and performance during typical activities, tyrosine appears to enhance performance when acute stress degrades function (such as when dieting or intense situations), thus making a great synergistic combination with enhanced body fat burning properties.<\/p>
N-Acetyl L-Carnitine: ALC is a modified amino acid that supports cellular energy production by assisting in the transport of fat into the mitochondria where it is converted into ATP (cellular fuel). ALC is a highly bioavailable form of carnitine that can cross the blood-brain barrier, where it helps to manage oxidative damage, supports mitochondrial function and helps to maintain normal neurotransmitter activity. Clinical studies suggest that ALC helps to maintain optimal neurological health.<\/p>
Green Coffee Extract: Coffee beans are actually green seeds inside a bright red berry. Roasting them turns the seeds brown and creates the characteristic aroma and flavor coffee lovers crave. To create green coffee bean extract, the seeds are left unroasted. Instead they're soaked and then concentrated to create the extract. This natural plant extract of unroasted coffee beans of the Robusta variety is standardized for polyphenols & chlorogenic acids. Along with diet and exercise, Green Coffee Bean Extract is a great way to support your overall weight loss.<\/p>
CapsiMax: Capsaicinoids are the bioactive and pungent principles in red hot pepper. Over 90 human clinical studies with more than 1000 subjects of varying ages, body weights and populations have studied the naturally functional properties of capsaicinoids and draw the same conclusion \u2013 when used alone and\/or in combination with other ingredients capsaicinoids support healthy weight management. However, to gain the benefits associated with capsaicinoids from food alone one would need to ingest 10 grams of red hot peppers every day.<\/p>
Bioperine: The ingredients we have in this formulation are way too good to not have them fully absorbed! Thus, Bioperine has been shown to significantly enhance the bioavailability of various supplement nutrients through increased absorption.<\/p>
*These statements have not been evaluated by the Food and Drug Administration. Products are not intended to diagnose, treat, cure or prevent any disease.<\/p>","gtin12":"665752696767","image":["https:\/\/siteimgs.com\/10017\/item\/synthalean-1wb-720x_1648056095-0.jpg"],"brand":"Axis Labs","url":"https:\/\/www.dpsnutrition.net\/i\/31871\/axis-labs-synthalean-xd-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"17.99","url":"https:\/\/www.dpsnutrition.net\/i\/31871\/axis-labs-synthalean-xd-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"Axis Labs Synthalean XD - 2 x 60 Capsule Bottles TWINPACK","sku":"AX2079","description":"
Introducing High-Potency SYNTHALEAN XD, Now with Dynamine!<\/p>
New and Improved? Yes! Synthalean XD now combines much of the power of Synthalean but now with Dynamine. Teacrine was a powerful component of the original Synthalean, but now Dynamine combined with Teacrine and Caffeine create a powerful stimulant combination that lasts all day without being uncomfortably strong. Additionally, Synthalean XD comes in a two (2) capsule serving, providing you with half the strength if it's not the right time for the a full serving.<\/p>
Advanced Fat Loss Technology<\/p>
Seriously, you can have it all with Axis Labs\u2019 innovative high-potency thermogenic, SYNTHALEAN XD. An advanced fat-loss technology, SYNTHALEAN XD is a body fat burning, weight loss jackhammer. The cutting edge burn supplement works synergistically to optimize your fat-burn naturally without energy crashes, jitters, and other unwelcome side effects. This unique blend of branded ingredients, backed by human research clinical studies \u2026 comes together in a ground breaking, FAT INCINERATING, ENERGY GENERATING, FOCUS INDUCING CAPSULE.<\/p>
The Secret Revealed<\/p>
Body Fat burning comes from tipping the formula of physical activity to calorie intake. Ultimately, burning more calories than you consume combined with your resting metabolic rate (the amount of calories you expend without exercise) results in rapid and managed weight loss that has lasting results.<\/p>
Over caffeinated products by themselves are not the answer. Too much caffeine causes jitters, the dreadful crash, and grogginess. SYNTHALEAN: is formulated with multiple natural stimulants that peaks at different times and gradually subsides so there\u2019s no crash, jitters, or grogginess. SYNTHALEAN: is strong. As a thermogenic, it boosts temperature and energy to literally melt fat. You can feel this fast-acting body fat burning supplement working. SYNTHALEAN: this potent fat-incinerating product works by combining the latest science has to offer to provide you with the greatest fat burning capacity.<\/p>
In development for over two years in countless versions, SYNTHALEAN XD improved alongside the ingredients and science. Our high-tech formulators used the best ingredients and scientifically formulated the synergy among the ingredients to create an incredible supplement to take for weight loss. Not only are we bringing you new, patented ingredients, but more importantly, ingredients that are safe and have been researched to work alone and together with some of the formulations other ingredients to allow for ultimate synergy and weight loss.<\/p>
Recently, a landmark clinical trial was conducted at a major Division I university to investigate Dynamine's potential pharmacokinetic interaction with caffeine and Teacrine. Remarkably, researchers discovered that Dynamine extended caffeine\u2019s half-life and increased its area under the curve approximately two-fold. The reverse was not true (i.e. caffeine did not alter Dynamine's pharmacokinetics). In addition, researchers also discovered that co-administration of Teacrine and Dynamine increased the half-life of caffeine approximately three-fold.<\/p>
SYNTHALEAN XD is a scientifically developed formulation designed to:<\/p>
It is super strength condensed into one or two capsules! Without the Unwanted Effects Everything You Need, Nothing You Don\u2019t<\/p>
Harsh stimulants and aggressive burn supplements are not required to stimulate body fat reduction. In fact, aggressive and high amounts of caffeine can unnecessarily tax your nervous system and leave you restless at night. Disturbances to sleep, mood, and focus are the opposite of what you need to optimize your body composition. No more peaks and valleys. Ups and downs. Jitters and shivers. Being alert one minute and then crashing and anxious the next.<\/p>
SYNTHALEAN XD is precision formulated to provide boundless energy that feels good and tapers gently to avoid crashing energy. With SYNTHALEAN XD, you can stay alert and awake, as well as burn fat all day long.<\/p>
Axis Labs has been providing unique and premium formulations for over 10 years. The makers of HYPERTEST XD, Myodex and HemodrauliX, Axis Labs is committed to the best ingredients in efficacious doses to provide superior quality of products for all your body fat burning supplementation needs.<\/p>
We have the willpower. We have the innovation. We have the next generation secret that will allow you to break through and break free of excess fat.<\/p>
Enough is enough: It\u2019s time for you to look in that mirror and be happy with what you see. No need to keep feeling \u201cover stimmed\u201d without results. Be alert, in the zone, and at your best. Lose the ceaseless hunger pangs. Metabolism optimized. Brain optimized. The best fat incinerator in the world period\u2026 in one capsule. Evolve past stimulants to the new and improved YOU with this revolutionary weight reduction supplement.<\/p>
Are you ready to change? Are you ready to look into the mirror and smile from ear to ear, filled with enthusiasm because of the battles and barriers you have overcome? If so, get SYNTHALEAN XD!<\/p>
Dynamine: Dynamine\u00ae is methylliberine, a purine alkaloid found in the kucha tea leaf. Its molecular structure is similar to theacrine (aka TeaCrine\u00ae) and is believed to behave in similar ways in the body. Like theacrine, methylliberine may amplify feelings of energy, mood and focus by activating dopamine receptors and other key neurotransmitters, inhibiting adenosine receptors, all without elevating heart rate or blood pressure.<\/p>
TeaCrine: Teacrine is a brand new patented ingredient (similar to caffeine) that provides clean, body fat burning energy without the crash or habituation. Teacrine has been shown to improve mood, energy, and focus all while helping you optimize and improve your energy expenditure. Properties include:<\/p>
L-TeaCrine: L-Theanine, when combined with Teacrine and caffeine, provides the ultimate combination. L Theanine will reduce the excitability caused by caffeine while retaining the focus and attention span benefits that caffeine provides. Not only does L-Theanine prevent from the \u201cover-stimmed\u201d conundrum, but research also suggests it can improve mental recovery after physical stress (i.e. working out) and cognitive performance. L-theanine, a branched-chain amino acid found in green tea leaves, has been linked to reducing mental stress and has relaxing effects without causing drowsiness (Juneja 1999).<\/p>
Caffeine: Caffeine, in combination with the aforementioned ingredients will really spice up this formula. Several studies have shown significant increases in intramuscular fat oxidation during exercise when caffeine was given prior to the bout. Caffeine combined with L-theanine and Teacrine create the ultimate trio of a balanced stimulant, fat oxidation, and clean energy feel.<\/p>
N-Acetyl Tyrosine: Tyrosine is the precursor of the catecholamine (CA), neurotransmitters dopamine (DA), norepinephrine (NE), and epinephrine. Tyrosine may preserve arousal during exercise and allow for prolonged and enhanced performance. While caffeine appears to improve focus and performance during typical activities, tyrosine appears to enhance performance when acute stress degrades function (such as when dieting or intense situations), thus making a great synergistic combination with enhanced body fat burning properties.<\/p>
N-Acetyl L-Carnitine: ALC is a modified amino acid that supports cellular energy production by assisting in the transport of fat into the mitochondria where it is converted into ATP (cellular fuel). ALC is a highly bioavailable form of carnitine that can cross the blood-brain barrier, where it helps to manage oxidative damage, supports mitochondrial function and helps to maintain normal neurotransmitter activity. Clinical studies suggest that ALC helps to maintain optimal neurological health.<\/p>
Green Coffee Extract: Coffee beans are actually green seeds inside a bright red berry. Roasting them turns the seeds brown and creates the characteristic aroma and flavor coffee lovers crave. To create green coffee bean extract, the seeds are left unroasted. Instead they're soaked and then concentrated to create the extract. This natural plant extract of unroasted coffee beans of the Robusta variety is standardized for polyphenols & chlorogenic acids. Along with diet and exercise, Green Coffee Bean Extract is a great way to support your overall weight loss.<\/p>
CapsiMax: Capsaicinoids are the bioactive and pungent principles in red hot pepper. Over 90 human clinical studies with more than 1000 subjects of varying ages, body weights and populations have studied the naturally functional properties of capsaicinoids and draw the same conclusion \u2013 when used alone and\/or in combination with other ingredients capsaicinoids support healthy weight management. However, to gain the benefits associated with capsaicinoids from food alone one would need to ingest 10 grams of red hot peppers every day.<\/p>
Bioperine: The ingredients we have in this formulation are way too good to not have them fully absorbed! Thus, Bioperine has been shown to significantly enhance the bioavailability of various supplement nutrients through increased absorption.<\/p>
*These statements have not been evaluated by the Food and Drug Administration. Products are not intended to diagnose, treat, cure or prevent any disease.<\/p>","gtin12":"665752696767","image":["https:\/\/siteimgs.com\/10017\/item\/axis-synth_1667315536-0.jpg"],"brand":"Axis Labs","url":"https:\/\/www.dpsnutrition.net\/i\/32543\/axis-labs-synthalean-xd-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"29.99","url":"https:\/\/www.dpsnutrition.net\/i\/32543\/axis-labs-synthalean-xd-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"Beverly International 7 Keto Musclean - 90 Capsules","sku":"BV023","description":"
The Ideal Fat-Loss Catalyst.<\/p>
7-Keto MuscLean is a rarity among fat-loss products: While other brands tout the latest \"magic bullet\", this formula has remained unchanged since 2003. That's because it continues to provide satisfying results to thousands of Beverly clients.<\/p>
Size: 90 capsules (30 servings)<\/p>
Benefits:<\/p>
Why people like it<\/p>
Who it\u2019s ideal for<\/p>
Secrets to Success<\/p>
What people are saying (The following testimonials have been sourced online and may have been edited for the sake of grammar and\/or space.)<\/p>
Sosh says: \"This is a superior fat-loss product to use in conjunction with a proper exercise and diet routine. Unlike popular, hyped-up products, this one works very effectively.\u201d<\/p>
Siglerj says: \"7-Keto Musclean provides a good, smooth energy boost, while at the same time boosting thermogenesis and suppressing my appetite.\u201d<\/p>
Angie2014 says: \"This product is great! After exercising for a few months all I was seeing were slow results. Once I started taking 7-Keto Musclean, I lost 17 lb in 3 weeks. It helped me steadily lose weight while suppressing appetite. I can tell a difference with energy levels and increased digestion. I love this stuff! I love Beverly products.\u201d<\/p>
IA says: \"I highly recommend the 7-Keto Musclean\/Lean Out stack. Wow! With the right diet, it is very rewarding. I recently went off of them for 3 weeks and could not wait to start again. I noticed a big change in my energy level and performance without them. Now I love my workouts with your products. Thank you so much!\u201d<\/p>
Delmar says: \"7-Keto Musclean is the best fat burner I have used that provides outstanding energy while not affecting my nervous system. I don't know about you but I absolutely hate feeling jittery!\u201d<\/p>
Gyminifitness says: \"I\u2019m definitely able to see more definition in a short period of time. Stacking this with Lean out and a clean diet is making a difference.\u201d<\/p>","gtin12":"857254000511","image":["https:\/\/siteimgs.com\/10017\/item\/51-7-keto-84925.16455607_1649440620-0.jpg","https:\/\/siteimgs.com\/10017\/item\/7-keto-musclean_1740677128-0.jpg"],"brand":"Beverly International","url":"https:\/\/www.dpsnutrition.net\/i\/950\/beverly-7-keto-musclean-90-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"31.99","url":"https:\/\/www.dpsnutrition.net\/i\/950\/beverly-7-keto-musclean-90-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Beverly International 7 Keto Musclean - 2 x 90 Capsule Bottles TWINPACK","sku":"BV2023","description":"
The Ideal Fat-Loss Catalyst.<\/p>
7-Keto MuscLean is a rarity among fat-loss products: While other brands tout the latest \"magic bullet\", this formula has remained unchanged since 2003. That's because it continues to provide satisfying results to thousands of Beverly clients.<\/p>
Size: 90 capsules (30 servings)<\/p>
Benefits:<\/p>
Why people like it<\/p>
Who it\u2019s ideal for<\/p>
Secrets to Success<\/p>
What people are saying (The following testimonials have been sourced online and may have been edited for the sake of grammar and\/or space.)<\/p>
Sosh says: \"This is a superior fat-loss product to use in conjunction with a proper exercise and diet routine. Unlike popular, hyped-up products, this one works very effectively.\u201d<\/p>
Siglerj says: \"7-Keto Musclean provides a good, smooth energy boost, while at the same time boosting thermogenesis and suppressing my appetite.\u201d<\/p>
Angie2014 says: \"This product is great! After exercising for a few months all I was seeing were slow results. Once I started taking 7-Keto Musclean, I lost 17 lb in 3 weeks. It helped me steadily lose weight while suppressing appetite. I can tell a difference with energy levels and increased digestion. I love this stuff! I love Beverly products.\u201d<\/p>
IA says: \"I highly recommend the 7-Keto Musclean\/Lean Out stack. Wow! With the right diet, it is very rewarding. I recently went off of them for 3 weeks and could not wait to start again. I noticed a big change in my energy level and performance without them. Now I love my workouts with your products. Thank you so much!\u201d<\/p>
Delmar says: \"7-Keto Musclean is the best fat burner I have used that provides outstanding energy while not affecting my nervous system. I don't know about you but I absolutely hate feeling jittery!\u201d<\/p>
Gyminifitness says: \"I\u2019m definitely able to see more definition in a short period of time. Stacking this with Lean out and a clean diet is making a difference.\u201d<\/p>","gtin12":"857254000511","image":["https:\/\/siteimgs.com\/10017\/item\/bv2023_1745857773-0.jpg","https:\/\/siteimgs.com\/10017\/item\/7-keto-musclean_1740677128-0.jpg"],"brand":"Beverly International","url":"https:\/\/www.dpsnutrition.net\/i\/35310\/beverly-international-7-keto-musclean-2-x-90.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"60.99","url":"https:\/\/www.dpsnutrition.net\/i\/35310\/beverly-international-7-keto-musclean-2-x-90.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Beverly International Lean Out - 120 Capsules","sku":"BV008","description":"
Breakthrough dietary supplement re-programs your body to burn fat. Now, you can achieve the lean, muscular look you desire - without unwanted side effects. No more jitters. No more heart palpitations. Safely cut hard to reach fat.<\/p>
Lean Out increases the utilization of stored fats for energy, sparing glycogen and amino acids. In essence, Lean Out shifts your fuel source utilization toward fats, leaving your amino acids and glycogen free to build muscle. If you want to improve your Muscle-to-Fat Ratio, Lean Out supplementation is a must.<\/p>
Take thermogenics to the next level. Thermogenics stimulate the central nervous system and cause an increase in body temperature resulting in more calories burned. Lean Out makes sure that the right fuel is burned. Your stored fat!<\/p>
Summary: Lean Out mobilizes fat from storage (also helping to prevent fat from sticking to artery walls) and promotes your cells to burn it for energy. It also acts as a \"tune up\" for the cell\u2019s mitochondria (where all energy is made) helping to prevent mitochondrial burnout, a major cause of metabolic aging.<\/p>
Anyone who is:<\/p>
Bring the intensity and make fat vanish with our complete multi-stage thermogenic The Magic Eraser. Our hard hitting fat loss formula is designed to assist in burning body fat while simultaneously providing clean energy, focus, and endurance to your most rigorous cardio sessions.<\/p>
The Magic Eraser is a fully loaded fat loss weapon built with ingredients to increase your overall energy and suppress your appetite to keep you on track whether you are in a caloric deficit or just trying to cut some weight to improve your overall look.<\/p>
Experience the best results with our Less Luck, More Skill Approach. The Magic Eraser is loaded with a special blend of hand crafted ingredients that over deliver when it comes to putting your body into fat burning mode. Bring your best physique to date with The Magic Eraser available now from Black Magic Supply.<\/p>","gtin13":"0746477744893","image":["https:\/\/siteimgs.com\/10017\/item\/black-magic-supply-magic_1965-0.jpg"],"brand":"Black Magic Supply Co.","url":"https:\/\/www.dpsnutrition.net\/i\/28850\/black-magic-supply-magic-eraser-84-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"44.99","url":"https:\/\/www.dpsnutrition.net\/i\/28850\/black-magic-supply-magic-eraser-84-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"Blackstone Labs Carnitrim - 60 Tablets","sku":"BLB88","description":"
L-Carnitine has been the darling of stimulant-free fat loss supplements for over a decade. The problem is that, while good in theory, regular L-Carnitine never really delivered tangible results in research settings. This is due to the fact that free form L-Carnitine frankly has terrible bioavailability, and really only works if you\u2019re chronically deficient in the essential nutrient. Blackstone Labs has transformed the prototypical L-Carnitine supplement into something elite in Carnitrim. Carnitrim is a stimulant-free energy and weight loss support supplement formulated to promote increased fat burning and weight loss as well as. Carnitrim harnesses the unique fat burning power of three highly bioavailable forms of carnitine, the biological \"taxi\u201d that shuttles fatty acids into the mitochondria where they can be utilized for fuel by the cell. It is ideal for any athlete looking to optimize performance, increase energy production, decrease soreness, and enhance recovery.<\/p>
Carniplex (250mg) our trademarked form of Carnitine Silicate which is an inositol-stabilized form that offers improved bioavailability, yielding greater carnitine uptake for enhanced fat burning and wound healing.<\/p>
Propionyl L-Carnitine (250mg)PLCAR, for short, this enhanced form of carnitine is known as the \"athlete\u2019s carnitine\u201d for its ability to boost nitric oxide production and support increased exercise performance.<\/p>
Carnipure (250mg) premium-grade L-Carnitine L-Tartrate documented to decrease the production of free radicals, muscle damage and muscle soreness after exercise. Carnipure has also been found to increase blood flow, reduce markers of metabolic stress, and improve recovery time. Note that all of these benefits come in addition to its role in supporting greater fat burning!<\/p>
EGCG (100mg) the most abundant catechin in green tea. It is heavily researched for its ability to promote lipolysis and increase the amount of fat used for energy both during and after exercise. Additional findings indicate that the powerful catechin may also help control body fat by inhibiting adipogenesis.<\/p>
As a dietary supplement, take one (1) tablet two (2) times per day. Do not exceed two (2) tablets daily.<\/p>","gtin12":"696302495387","image":["https:\/\/siteimgs.com\/10017\/item\/blackstone-labs-carnitrim_2062-0.jpg"],"brand":"Blackstone Labs","url":"https:\/\/www.dpsnutrition.net\/i\/29047\/blackstone-labs-carnitrim-60-tablets.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"27.99","url":"https:\/\/www.dpsnutrition.net\/i\/29047\/blackstone-labs-carnitrim-60-tablets.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"Blackstone Labs Evaporate - 60 Capsules","sku":"BLB63","description":"
Losing weight and getting in better shape is relatively easy and can be accomplished with fairly small changes to your diet and exercise plan. Getting absolutely shredded is a whole other ballgame.<\/p>
Simply moving less and eating more isn\u2019t enough to get peeled. For that, you need to dial in every last milligram of food, water, and salt. But even then, that might not be enough to get you stage lean.<\/p>
For those occasions when you need to be ripped, you need Evaporate! Evaporate is a competition-strength water elimination supplement scientifically formulated to help flush excess water out of the body. Due to the extreme potency of Evaporate, it is not intended for prolonged use. Vitamin B6 (100mg) reduces built up bodily fluids due to its water retention reducing properties. Magnesium (50mg) A vital mineral that helps reduce water retention in the body. Additionally, Magnesium also has been shown to help provide muscular strength and can alleviate high blood pressure.<\/p>
Taraxacum Officinale Extract (2000mg) Acts as an anti-inflammatory and reduces muscle spasms. Commonly used a natural diuretic, it also has been used in herbal medicines as a mild laxative and helps improve digestion.<\/p>
Uva Ursi Extract (1000mg) Acts as a diuretic and contains ursolic acid, powerful astringents, and helps promote the growth of healthy new cells. It is also used to help reduce inflammation, increase urine flow, and reduce bloating and water retention.<\/p>
Tropaeolum Majus (500mg) Helps to directly increase urinary flow and is also a good source of Vitamin C Green Tea Extract (300mg) Enhances thermogenesis, metabolism, and fat oxidation resulting in greater fat burning during exercise and while at rest. Horsetail (250mg) Increases urine production and has gained popularity as a treatment for kidney stones and UTI's. Taurine (150mg) Helps alleviate high blood pressure, aids digestion, and helps reduce water retention and bloating.<\/p>
As a dietary supplement, take three (3) capsules after morning meal and three (3) capsules after mid-day meal, along with sixteen (16) ounces of water. Drink at least six (6) to eight (8) 8 ounce glasses of water daily. Do not exceed recommended dose.<\/p>","gtin12":"650348782375","image":["https:\/\/siteimgs.com\/10017\/item\/evaporate-2000x_1665698468-0.jpg"],"brand":"Blackstone Labs","url":"https:\/\/www.dpsnutrition.net\/i\/28733\/blackstone-labs-evaporate-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"23.99","url":"https:\/\/www.dpsnutrition.net\/i\/28733\/blackstone-labs-evaporate-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"Blackstone Labs Evaporate - 2 x 60 Capsule Bottles TWINPACK","sku":"BLB263","description":"
Losing weight and getting in better shape is relatively easy and can be accomplished with fairly small changes to your diet and exercise plan. Getting absolutely shredded is a whole other ballgame.<\/p>
Simply moving less and eating more isn\u2019t enough to get peeled. For that, you need to dial in every last milligram of food, water, and salt. But even then, that might not be enough to get you stage lean.<\/p>
For those occasions when you need to be ripped, you need Evaporate! Evaporate is a competition-strength water elimination supplement scientifically formulated to help flush excess water out of the body. Due to the extreme potency of Evaporate, it is not intended for prolonged use. Vitamin B6 (100mg) reduces built up bodily fluids due to its water retention reducing properties. Magnesium (50mg) A vital mineral that helps reduce water retention in the body. Additionally, Magnesium also has been shown to help provide muscular strength and can alleviate high blood pressure.<\/p>
Taraxacum Officinale Extract (2000mg) Acts as an anti-inflammatory and reduces muscle spasms. Commonly used a natural diuretic, it also has been used in herbal medicines as a mild laxative and helps improve digestion.<\/p>
Uva Ursi Extract (1000mg) Acts as a diuretic and contains ursolic acid, powerful astringents, and helps promote the growth of healthy new cells. It is also used to help reduce inflammation, increase urine flow, and reduce bloating and water retention.<\/p>
Tropaeolum Majus (500mg) Helps to directly increase urinary flow and is also a good source of Vitamin C Green Tea Extract (300mg) Enhances thermogenesis, metabolism, and fat oxidation resulting in greater fat burning during exercise and while at rest. Horsetail (250mg) Increases urine production and has gained popularity as a treatment for kidney stones and UTI's. Taurine (150mg) Helps alleviate high blood pressure, aids digestion, and helps reduce water retention and bloating.<\/p>
As a dietary supplement, take three (3) capsules after morning meal and three (3) capsules after mid-day meal, along with sixteen (16) ounces of water. Drink at least six (6) to eight (8) 8 ounce glasses of water daily. Do not exceed recommended dose.<\/p>","gtin12":"650348782375","image":["https:\/\/siteimgs.com\/10017\/item\/blb263_1742483817-0.jpg"],"brand":"Blackstone Labs","url":"https:\/\/www.dpsnutrition.net\/i\/35137\/blackstone-labs-evaporate-2-x-60-capsule-bottles.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.82","url":"https:\/\/www.dpsnutrition.net\/i\/35137\/blackstone-labs-evaporate-2-x-60-capsule-bottles.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"Blackstone Labs Fla-2 Stim Free Fat Burner Granny's Tea - 60 Servings","sku":"BLB193","description":"
FLA-2<\/p>\r\n
Non-stimulant fat burner
Assists the body to use fatty acids for energy
Can be stacked with stimulant based fat burners
Can be cycled year -round<\/p>\r\n
Ingredients
Chromium Picolinate (200mcg) improves insulin function which helps normalize blood sugar levels and improve blood sugar utilization. Chromium also supports a healthy metabolism and storage of nutrients, since it aids nutrient absorption and distribution of carbs, fats, and proteins consumed from the diet. Research has also noted that higher chromium intakes are associated with a reduction in adipose (fat) tissue.<\/p>\r\n
Calcium Pyruvate (4g) increases the body’s use of fat as an energy source for cellular respiration thereby increasing metabolic rate, and resting metabolism, to burn more calories throughout the day. Pyruvate also enhances delivery of protein and carbs into muscle cells as well as the amount of ATP available to mitochondria, supporting energy production.<\/p>\r\n
Garcinia Cambogia (750mg) contains hydroxycitric acid (HCA), a compound known to inhibit citrate lyase, an enzyme required by the body to synthesize fat. Negating the activity of citrate lyase reduces your body’s ability to store fat, thus encouraging fat burning. Research has also indicated that HCA can reduce appetite and increase satiety.<\/p>\r\n
L-Carnitine L-Tartrate (500mg) enhances fat burning by facilitating the transfer of long-chain fatty acids, such as triglycerides, into the mitochondria where they can be oxidized to produce energy. L-Carnitine L-Tartrate also has been shown to accelerate recovery from exercise and reduce muscle soreness.<\/p>\r\n
Recommended Use
Directions
As a dietary supplement, mix one (1) scoop in 8-10 oz. of water upon waking up. An additional scoop can be taken in the evening before bed. Do not exceed three (3) scoops daily.<\/p>\r\n
<\/p>\r\n
<\/p>","gtin12":"811836027907","image":["https:\/\/siteimgs.com\/10017\/item\/fla-2-grannys-tea-600x857_1726589422-0.jpg"],"brand":"Blackstone Labs","url":"https:\/\/www.dpsnutrition.net\/i\/34521\/blackstone-labs-fla-2-stim-free-fat-burner-granny.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"34.99","url":"https:\/\/www.dpsnutrition.net\/i\/34521\/blackstone-labs-fla-2-stim-free-fat-burner-granny.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Blackstone Labs Fla-2 Stim Free Fat Burner Mango Burst - 60 Servings","sku":"BLB194","description":"
FLA-2<\/p> \r\n
Non-stimulant fat burner
Assists the body to use fatty acids for energy
Can be stacked with stimulant based fat burners
Can be cycled year -round<\/p>\r\n
Ingredients
Chromium Picolinate (200mcg) improves insulin function which helps normalize blood sugar levels and improve blood sugar utilization. Chromium also supports a healthy metabolism and storage of nutrients, since it aids nutrient absorption and distribution of carbs, fats, and proteins consumed from the diet. Research has also noted that higher chromium intakes are associated with a reduction in adipose (fat) tissue.<\/p>\r\n
Calcium Pyruvate (4g) increases the body’s use of fat as an energy source for cellular respiration thereby increasing metabolic rate, and resting metabolism, to burn more calories throughout the day. Pyruvate also enhances delivery of protein and carbs into muscle cells as well as the amount of ATP available to mitochondria, supporting energy production.<\/p>\r\n
Garcinia Cambogia (750mg) contains hydroxycitric acid (HCA), a compound known to inhibit citrate lyase, an enzyme required by the body to synthesize fat. Negating the activity of citrate lyase reduces your body’s ability to store fat, thus encouraging fat burning. Research has also indicated that HCA can reduce appetite and increase satiety.<\/p>\r\n
L-Carnitine L-Tartrate (500mg) enhances fat burning by facilitating the transfer of long-chain fatty acids, such as triglycerides, into the mitochondria where they can be oxidized to produce energy. L-Carnitine L-Tartrate also has been shown to accelerate recovery from exercise and reduce muscle soreness.<\/p>\r\n
Recommended Use
Directions
As a dietary supplement, mix one (1) scoop in 8-10 oz. of water upon waking up. An additional scoop can be taken in the evening before bed. Do not exceed three (3) scoops daily.<\/p>\r\n
<\/p>\r\n
<\/p>","gtin12":"811836027914","image":["https:\/\/siteimgs.com\/10017\/item\/fla-2-mango-burst-600x857_1726590144-0.jpg"],"brand":"Blackstone Labs","url":"https:\/\/www.dpsnutrition.net\/i\/34524\/blackstone-labs-fla-2-stim-free-fat-burner-mango.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"34.99","url":"https:\/\/www.dpsnutrition.net\/i\/34524\/blackstone-labs-fla-2-stim-free-fat-burner-mango.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Blackstone Labs Paraburn - 60 Capsules","sku":"BLB48","description":"
Paraburn Intense Energy<\/p>
The problem with virtually all fat burners these days is that they\u2019re nothing but a mish-mash of stimulants that do little in the way of actual fat burning. A serving of some mass-market fat loss supplement is more prone to give you jitters or a nasty crash than actually enhance your weight loss efforts.<\/p>
That\u2019s where Paraburn differs. This revolutionary fat burner uses proven ingredients that burn fat, suppress appetite, and increase energy expenditure without a litany of strange, unproven stimulants. Each serving provides a modest dose of caffeine alongside research-backed non-stimulant fat reducers, yielding a formula that helps you drop fat faster than ever!<\/p>
Caffeine provides the foundation of all effective fat burners. It energizes the CNS, enhancing energy, mood, and alertness -- all of which suffer during dieting. Furthermore, caffeine also helps suppress appetite and stimulate lipolysis. Paraburn includes an extremely appropriate 250mg per capsule of caffeine, enough to keep you upbeat and alert without making you feel jittery or overly-stimmed.<\/p>
Also known as \"devil\u2019s horsewhip, this powerful Ayurvedic herb offers a number of benefits to those seeking to drop fat fast. First Achyranthes Aspera enhances thyroid function, increasing metabolic rate and calorie burn each day. It also reduces blood sugar levels and decreases appetite, and some research notes it may prevent some carbohydrate and fat digestion.<\/p>
Is a xanthine-like molecule similar to caffeine that stimulates the CNS but not as aggressively as caffeine. Theobromine provides smooth, long-lasting energy and helps prevent any crash associated with caffeine use. It also improves insulin sensitivity, which helps avoid the peaks and valleys of blood sugar spikes, which can induce bouts of ravenous hunger.<\/p>
The pungent alkaloid present in chile peppers that gives them their heat. Capsaicin has been well documented to increase energy expenditure, enhance fat burning, and inhibit fat accumulation. Don\u2019t be surprised if you feel the burn with this ingredient!<\/p>
Found in ginger and Grains of Paradise, 6-paradol is a pungent aromatic that\u2019s an extremely powerful non-stimulant fat burning supplement. Much like capsaicin, 6-paradol increases thermogenesis via activation of brown adipose tissue, resulting in greater energy expenditure. But that\u2019s not all, 6-paradol also reduces blood sugar and decreases visceral fat making it one of the top researched products for anti-fat by scientists today.<\/p>
T3 is a well-known thyroid activator but is known to have some pretty nasty side effects. Paraburn utilizes 3,3-diiodothyronine (T2), which is similar to T3, but won\u2019t lead to permanent thyroid shutdown like T3 supplementation will. T2 converts into T3, giving you the metabolism boosting benefits T3 supplementation but without the inevitable shutdown that occurs with rampant T3 use. The end results is better thyroid function, greater calorie burning, and ultimately, faster fat loss<\/p>
As a dietary supplement, take one (1) to two (2) capsules up to two (2) times per day 20 minutes before a meal. Do not exceed four (4) capsules per day.<\/p>","gtin12":"650348782740","image":["https:\/\/siteimgs.com\/10017\/item\/paraburn-2000x_1666015881-0.jpg"],"brand":"Blackstone Labs","url":"https:\/\/www.dpsnutrition.net\/i\/27588\/blackstone-labs-paraburn-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"32.66","url":"https:\/\/www.dpsnutrition.net\/i\/27588\/blackstone-labs-paraburn-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Blackstone Labs Paraburn - 2 x 60 Capsule Bottles TWINPACK","sku":"BLB248","description":"
Paraburn Intense Energy<\/p>
The problem with virtually all fat burners these days is that they\u2019re nothing but a mish-mash of stimulants that do little in the way of actual fat burning. A serving of some mass-market fat loss supplement is more prone to give you jitters or a nasty crash than actually enhance your weight loss efforts.<\/p>
That\u2019s where Paraburn differs. This revolutionary fat burner uses proven ingredients that burn fat, suppress appetite, and increase energy expenditure without a litany of strange, unproven stimulants. Each serving provides a modest dose of caffeine alongside research-backed non-stimulant fat reducers, yielding a formula that helps you drop fat faster than ever!<\/p>
Caffeine provides the foundation of all effective fat burners. It energizes the CNS, enhancing energy, mood, and alertness -- all of which suffer during dieting. Furthermore, caffeine also helps suppress appetite and stimulate lipolysis. Paraburn includes an extremely appropriate 250mg per capsule of caffeine, enough to keep you upbeat and alert without making you feel jittery or overly-stimmed.<\/p>
Also known as \"devil\u2019s horsewhip, this powerful Ayurvedic herb offers a number of benefits to those seeking to drop fat fast. First Achyranthes Aspera enhances thyroid function, increasing metabolic rate and calorie burn each day. It also reduces blood sugar levels and decreases appetite, and some research notes it may prevent some carbohydrate and fat digestion.<\/p>
Is a xanthine-like molecule similar to caffeine that stimulates the CNS but not as aggressively as caffeine. Theobromine provides smooth, long-lasting energy and helps prevent any crash associated with caffeine use. It also improves insulin sensitivity, which helps avoid the peaks and valleys of blood sugar spikes, which can induce bouts of ravenous hunger.<\/p>
The pungent alkaloid present in chile peppers that gives them their heat. Capsaicin has been well documented to increase energy expenditure, enhance fat burning, and inhibit fat accumulation. Don\u2019t be surprised if you feel the burn with this ingredient!<\/p>
Found in ginger and Grains of Paradise, 6-paradol is a pungent aromatic that\u2019s an extremely powerful non-stimulant fat burning supplement. Much like capsaicin, 6-paradol increases thermogenesis via activation of brown adipose tissue, resulting in greater energy expenditure. But that\u2019s not all, 6-paradol also reduces blood sugar and decreases visceral fat making it one of the top researched products for anti-fat by scientists today.<\/p>
T3 is a well-known thyroid activator but is known to have some pretty nasty side effects. Paraburn utilizes 3,3-diiodothyronine (T2), which is similar to T3, but won\u2019t lead to permanent thyroid shutdown like T3 supplementation will. T2 converts into T3, giving you the metabolism boosting benefits T3 supplementation but without the inevitable shutdown that occurs with rampant T3 use. The end results is better thyroid function, greater calorie burning, and ultimately, faster fat loss<\/p>
As a dietary supplement, take one (1) to two (2) capsules up to two (2) times per day 20 minutes before a meal. Do not exceed four (4) capsules per day.<\/p>","gtin12":"650348782740","image":["https:\/\/siteimgs.com\/10017\/item\/blb248_1742483869-0.jpg"],"brand":"Blackstone Labs","url":"https:\/\/www.dpsnutrition.net\/i\/35134\/blackstone-labs-paraburn-2-x-60-capsule-bottles.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"52.90","url":"https:\/\/www.dpsnutrition.net\/i\/35134\/blackstone-labs-paraburn-2-x-60-capsule-bottles.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Bucked Up LFG Pre-Workout Berry - 30 Servings","sku":"BU187","description":"
Announcing LFG, a revolutionary pre-workout specifically designed to optimize fat loss. Designed to complement your hard work, LFG acts as both a pre-workout and a fat burning supplement. This science-based, non-proprietary formula supplies breakthrough ingredients to help you achieve your noble quest for fat loss.*<\/p>
LFG<\/p>
You know what\u2019s needed to win the war against unwanted fat. You work hard, pushing your limits, burning any fatty obstacles that dare oppose your weight loss goals. You deserve supplements that work as hard as you do.<\/p>
BUCKED UP LFG fuses familiar compounds with groundbreaking new fat-loss ingredients to give you a pre-workout experience as powerful as your work ethic.<\/p>
Training with LFG is the equivalent of throwing fat stores on the stove and cranking burners up to max. Set by set & sprint by sprint, combine your hard work with LFG\u2019s body-heating thermogenesis, and bring fat to a steady boil. Evaporate unwanted weight and transform.<\/p>
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.<\/p>","gtin12":"811374037482","image":["https:\/\/siteimgs.com\/10017\/item\/1645134601-bu-lfg-berry-2_1647021500-0.jpg"],"brand":"Bucked Up","url":"https:\/\/www.dpsnutrition.net\/i\/31826\/bucked-up-lfg-pre-workout-berry-30-servings.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"38.47","url":"https:\/\/www.dpsnutrition.net\/i\/31826\/bucked-up-lfg-pre-workout-berry-30-servings.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Bucked Up LFG Pre-Workout Razzle Dazzle - 30 Servings","sku":"BU189","description":"
Announcing LFG, a revolutionary pre-workout specifically designed to optimize fat loss. Designed to complement your hard work, LFG acts as both a pre-workout and a fat burning supplement. This science-based, non-proprietary formula supplies breakthrough ingredients to help you achieve your noble quest for fat loss. LFG<\/p>
You know what\u2019s needed to win the war against unwanted fat. You work hard, pushing your limits, burning any fatty obstacles that dare oppose your weight loss goals. You deserve supplements that work as hard as you do.<\/p>
BUCKED UP LFG fuses familiar compounds with groundbreaking new fat-loss ingredients to give you a pre-workout experience as powerful as your work ethic.<\/p>
Training with LFG is the equivalent of throwing fat stores on the stove and cranking burners up to max. Set by set & sprint by sprint, combine your hard work with LFG\u2019s body-heating thermogenesis, and bring fat to a steady boil. Evaporate unwanted weight and transform.<\/p>
Announcing LFG, a revolutionary pre-workout specifically designed to optimize fat loss. Designed to complement your hard work, LFG acts as both a pre-workout and a fat burning supplement. This science-based, non-proprietary formula supplies breakthrough ingredients to help you achieve your noble quest for fat loss.<\/p>
LFG\nYou know what\u2019s needed to win the war against unwanted fat. You work hard, pushing your limits, burning any fatty obstacles that dare oppose your weight loss goals. You deserve supplements that work as hard as you do.<\/p>
BUCKED UP LFG fuses familiar compounds with groundbreaking new fat-loss ingredients to give you a pre-workout experience as powerful as your work ethic.<\/p>
Training with LFG is the equivalent of throwing fat stores on the stove and cranking burners up to max. Set by set & sprint by sprint, combine your hard work with LFG\u2019s body-heating thermogenesis, and bring fat to a steady boil. Evaporate unwanted weight and transform.<\/p>
<\/p>\r\n
High Energy Advanced Thermogenic Fat Burner Fat Loss, Energy, Focus, & Appetite Control Fast Acting, Long Lasting Energy 12 Premium Active Ingredients Per Daily Dose (2 servings):<\/p>\r\n
Lipo Elite is an advanced thermogenic fat burner that is designed to support increases in fat burning, metabolism, energy, focus, and appetite control.<\/p>\r\n
Ask Yourself a Few Questions: Do you want to lose body-fat? Do you need fast-acting, long-lasting energy and focus? Are you self-conscious about your appearance? Has your weight loss hit a sticking point? Is your appetite out of control and holding you back? Do you want to achieve maximum results as quickly as possible? Are you tired of working hard to build lean muscle to lose it when trying to lose fat? Do you feel like you just can’t get started or lack ambition to try to lose weight &\/or get back in shape?<\/p>\r\n
^^^ If you answered yes to any of the above questions, Lipo Elite may be right for you.<\/p>\r\n
MitoBurn® (L-BAIBA): MitoBurn® is a revolutionary fat incinerating ingredient.<\/p>\r\n
Gamma-butyrobetaine (GBB) is a precursor to L-Carnitine that has the ability to increase the body’s production of L-Carnitine and help improve energy levels, fat loss, athletic performance, and more.<\/p>\r\n
GBB can also help support thermogenesis as evidenced by the increased sweating that some feel when using GBB which has led some people to say that they ‘feel the fat melting off’. Of course, that is an exaggeration but is a good indication of the great fat burning results that many feel from GBB.<\/p>\r\n
Caffeine Anhydrous is the staple ingredient in many fat loss and energy products and for good reason.<\/p>\r\n
Caffeine has also been shown to improve exercise performance and has a key role in increasing energy, mental focus, mood, cognitive ability, and has potential synergistic effects with other key ingredients in Lipo Elite.<\/p>\r\n
Theobromine is a methylxanthine and is the ‘feel good’ ingredient in chocolate. The relaxed feeling that one experiences after chocolate consumption can be attributed to theobromine.<\/p>\r\n
Some people get confused in comparing theobromine to caffeine. Theobromine is a methylxanthine and therefore chemically related to caffeine, but the effects are very different. The energy from theobromine is commonly described as a sustained long lasting relaxed feel-good energy without a crash.<\/p>\r\n
Synephrine is a naturally occurring substance found in plants that has been used for thousands of years in Traditional Chinese Medicine (TCM) and is found mainly in Citrus Aurantium\/Orange peels. Synephrine has been commonly used to help burn fat, suppress appetite, and increase energy. The energy from Synephrine is commonly described as a clean energy without the crash associated with some other stimulants.<\/p>\r\n
It seems like with every day that goes by, most of us find ourselves leading increasingly stressful lives and stress is something that can take a toll on us, both emotionally and physically. Sustained levels of stress can be detrimental to both our physical and mental health. This can take a toll on our relationships, jobs, hobbies, and our appearance.<\/p>\r\n
KannaEase™ is included in Lipo Elite to both help the energizing effects be smoother and without the crash associated with many stimulant-based fat burners and also to help keep your mind off of the stresses of day-to-day life and focused on your goals instead of on food.<\/p>\r\n
Highlights\/Supports:<\/p>\r\n
1,000 mg. MitoBurn 250 mg. Hops (std. for Isohumulones) 250 mg. SEA (Stearoylethanolamide) 100 mg. OEA (Oleoylethanolamide) 75 mg. CaloriBurn 25 mg. AstraGin 10 mg. Bioperine<\/p>\r\n
LipoVantage is an ultra-potent stimulant free fat burner and natural exercise mimetic that is designed to help you burn stubborn body-fat and get the maximum results out of your diet &\/or exercise regimen.<\/p>\r\n
^^^ If you answered yes to any of these questions, LipoVantage may be right for you.<\/p>\r\n
LipoVantage is great for athletes trying to get to get the most out of their workouts, individuals trying to lose weight and amplify their diet and workouts, people looking to maintain lean muscle while losing fat, and by anyone who is looking to improve body-composition, get leaner, and be more fit.<\/p>\r\n
LipoVantage can be used by both men and women.<\/p>\r\n
LipoVantage isn’t just another fat burner thrown together with popular trendy ingredients to get a sale. As a matter of fact, even many supplement enthusiasts may be familiar with some of the super exciting ingredients that make LipoVantage so unique and so effective.<\/p>\r\n
LipoVantage is a scientifically designed precision formulation of active ingredients that is not only designed to help you maximize fat loss through a variety of exciting pathways but to also help you retain lean muscle while doing it.<\/p>\r\n
Here are just some of the ways that the ingredients in LipoVantage may help support your fat loss goals:<\/p>\r\n
Revolutionary Multi-Ingredient PPAR Activation Formula<\/p>\r\n
In the simplest terms, this applies to fat loss and the importance of a basic understanding of it will become more clear as you read through the ingredient descriptions below.<\/p>\r\n
The Peroxisome Proliferator-Activated Receptor (PPAR) family is divided into three subgroups – alpha, delta\/beta, and gamma. PPARalpha is highly expressed in muscle, the liver, kidneys, and heart and is involved in the regulation of lipid metabolism, specifically the transcription of the genes involved in the beta-oxidation (burning) of fatty acids and lipogenesis (storage of fatty acids).<\/p>\r\n
Fat can be oxidized in the mitochondria and peroxisomes of cells, with the majority of this oxidation occurring in skeletal muscle cells and the liver.<\/p>\r\n
PPAR-alpha activation increases fat oxidation in the mitochondria and peroxisomes by increasing the expression of enzymes involved in beta-oxidation of fatty acids. In addition, PPAR-alpha activation also increased the number or peroxisomes and mitochondria. This combination of an increased number of peroxisomes and mitochondria plus the increase in beta-oxidation of fatty acids increases the rate and capacity at which fat can be burned.<\/p>\r\n
In simple terms, the activation of PPAR-alpha would be very beneficial to those looking to burn fat.<\/p>\r\n
MitoBurn® is a revolutionary fat incinerating ingredient.<\/p>\r\n
Hops is an herb that people tend to most commonly associate with relaxation and being one of the ingredients in beer. With Hops, as with many herbs, it’s not the herb itself that is most significant, it’s what the herb is standardized\/extracted for that makes the difference – in this case, Isohumulones.<\/p>\r\n
Isohumulones (iso-α-acids) are a natural flavonoid found in hops and are the major bitter components in beer and come from the female hops plant (Humulus lupulus L.).<\/p>\r\n
Isohumulones (iso-α-acids) have been shown to help obese individuals with prediabetes by supporting reducing hyperglycemia, the lowering of blood sugar, improved insulin sensitivity (decreased insulin resistance), and increased fat loss; thereby supporting improving some of the underlying markers of metabolic syndrome.<\/p>\r\n
Stearoylethanolamide (SEA) is a fatty acid amide and endocannabinoid neurotransmitter that has been shown to support a decrease in food intake (support appetite control) and support fat loss independent of the PPAR pathway.<\/p>\r\n
In addition to its fat loss and appetite control support benefits, SEA may also have possible neuroprotective and anti-inflammatory benefits.<\/p>\r\n
Oleoylethanolamide (OEA) is an exogenous lipid synthesized in the intestines that has been shown to have anorexic properties, meaning that it decreases food intake (supports appetite control).<\/p>\r\n
OEA is also an activator of Peroxisome Proliferator-Activator Receptor Alpha (PPAR-alpha). Activation of PPAR-alpha supports an increase in fat oxidation (the breaking down of fatty acids) along with a decrease in fat storage, thereby creating an ideal environment for fat loss.<\/p>\r\n
CaloriBurn GP® is a standardized extract of the Grains of Paradise seed, also known as Aframomum Melegueta, a spice native to West Africa that belongs to the same family as ginger. CaloriBurn GP® is ideal for those looking for improved body-composition and enhanced fat loss.<\/p>\r\n
AstraGin® is a natural patented ingredient complex comprised of highly fractionated Astragalus membranaceus and Panax notoginseng and created using pharmaceutical grade extraction and processing technology and designed to help enhance nutrient absorption.<\/p>\r\n
In short, AstraGin® is designed to help make sure you properly absorb the other great nutrients in LipoVantage for maximum results.<\/p>\r\n
Bioperine® is a standardized extract from the fruit of Piper nigrum L (Black Pepper) containing 95% piperine. Piperine has been shown to enhance the oral bioavailability of many ingredients.<\/p>\r\n
Bioperine® is included in LipoVantage to be the perfect one-two punch with AstraGin® to help ensure that you properly absorb and get the maximum benefits out of all of the awesome ingredients in the comprehensive LipoVantage formulation.<\/p>\r\n
LipoVantage can be stacked with CEL Lipo Elite, M-Test, Epi-Plex, Api-Plex, Anabolic Effect, or a variety of other Competitive Edge Labs products for improved synergistic results.<\/p>\r\n
Stack usage suggesstion:<\/strong><\/p>\r\n High Energy Advanced Thermogenic Fat Burner Fat Loss, Energy, Focus, & Appetite Control Fast Acting, Long Lasting Energy<\/p> 12 Premium Active Ingredients Per Daily Dose (2 servings): Lipo Elite is an advanced thermogenic fat burner that is designed to support increases in fat burning, metabolism, energy, focus, and appetite control.<\/p> Ask Yourself a Few Questions: Do you want to lose body-fat? Do you need fast-acting, long-lasting energy and focus? Are you self-conscious about your appearance? Has your weight loss hit a sticking point? Is your appetite out of control and holding you back? Do you want to achieve maximum results as quickly as possible? Are you tired of working hard to build lean muscle to lose it when trying to lose fat? Do you feel like you just can't get started or lack ambition to try to lose weight &\/or get back in shape?<\/p>","gtin12":"891192002374","image":["https:\/\/siteimgs.com\/10017\/item\/lipo-elite_1688832550-0.jpg"],"brand":"Competitive Edge Labs CEL","url":"https:\/\/www.dpsnutrition.net\/i\/33282\/competitive-edge-labs-lipo-elite-2-x-90-cap-btls.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"79.99","url":"https:\/\/www.dpsnutrition.net\/i\/33282\/competitive-edge-labs-lipo-elite-2-x-90-cap-btls.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Competitive Edge Labs Lipo Elite - 90 Capsules","sku":"CG033","description":" Highlights\/Supports:<\/p> High Energy Advanced Thermogenic Fat Burner Fat Loss, Energy, Focus, & Appetite Control Fast Acting, Long Lasting Energy<\/p> 12 Premium Active Ingredients Per Daily Dose (2 servings):<\/p> Lipo Elite is an advanced thermogenic fat burner that is designed to support increases in fat burning, metabolism, energy, focus, and appetite control.<\/p> Ask Yourself a Few Questions: Do you want to lose body-fat? Do you need fast-acting, long-lasting energy and focus? Are you self-conscious about your appearance? Has your weight loss hit a sticking point? Is your appetite out of control and holding you back? Do you want to achieve maximum results as quickly as possible? Are you tired of working hard to build lean muscle to lose it when trying to lose fat? Do you feel like you just can\u2019t get started or lack ambition to try to lose weight &\/or get back in shape?<\/p> ^^^ If you answered yes to any of the above questions, Lipo Elite may be right for you.<\/p> MitoBurn\u00ae (L-BAIBA): MitoBurn\u00ae is a revolutionary fat incinerating ingredient.<\/p> BAIBA (\u03b2-aminoisobutyric acid) is an amino acid that can be found naturally in both plant and animal sources but that until now hasn\u2019t been widely commercially available as a raw material ingredient due to the inability to keep it stable as a powder and procure it in its most biologically active type, L-BAIBA.<\/p> L-BAIBA, a metabolite of the amino acid L-Valine, is a powerful myokine (also known as \u2018exercise factors\u2019) and has the ability to stimulate certain \u2018exercise factors\u2019 that are released from skeletal muscle in response to muscular stress, especially muscle contraction.<\/p> L-BAIBA plays an important role in the benefits of regular exercise and is the starting point for a positive sequence of events including increased free fatty acid oxidization, improved glucose uptake, and reduced body fat.<\/p> L-BAIBA works through multiple pathways. The primary one is though initiating the \u2018browning\u2019 of white adipose (fat) tissue, which increases energy expenditure, improves insulin sensitivity, and helps regulate weight management. A very novel one is that it has also been shown to help decrease the \u2018beiging\u2019 of adipose tissue. This \u2018beiging\u2019 process is when the body reverses the preferred adipose tissue color of brown (high energy usage) back to white (high energy storage).<\/p> L-BAIBA levels are associated with many of exercise\u2019s numerous benefits, including amplifying the fat burning effects of exercise so you see results faster.<\/p> MitoBurn\u00ae is the first clinically tested and verified form of L-BAIBA.<\/p> MitoBurn\u00ae (L-BAIBA) Highlights\/Supports:<\/p> MitoBurn\u00ae (L-BAIBA) as a PPAR Activator:<\/p> The significance of Peroxisome Proliferator-Activated Receptor (PPAR) activation is discussed in detail in a separate section of this write up. In simple terms, PPAR-alpha activation does a lot of the work that we desire for when exercising and trying to burn fat.<\/p> There is so much excitement about MitoBurn\u00ae as an exercise mimetic that many people often overlook that L-BAIBA is also a potent PPAR-alpha activator. This is one of the mechanisms through which L-BAIBA supports the browning of white adipose tissue and the increase in beta oxidation (the process in which fat is broken down for use as energy by the body) and decrease in fat creation<\/p> Cocoabuterol\u00ae is a specialized natural cocoa (Theobroma cacao L.) extract that is custom engineered to contain the most bioactive compounds using the latest technologies. The major active ingredients in Cocoabuterol\u00ae are natural polyphenols and alkaloids, including N-Coumaroyldoamine, N-Caffeoyldopamine, and many more. All of these naturally occurring phytochemicals have a variety of incredible benefits throughout the body.<\/p> Cocoabuterol\u00ae supports fat loss through multiple pathways, a key one of which is its potent ability to help redirect the body from using muscle protein to instead start using stored fat and thereby making each workout more effective when trying to lose body-fat.<\/p> Cocoabuterol supports improved insulin sensitivity and promotes a slight diuretic effect. This supports helping you better utilize your carbohydrates and to draw out excess water, leaving you with a leaner, harder, dryer, and more toned appearance.<\/p> Cocoabuterol\u00ae is so commonly associated with fat loss that many overlook its potential muscle building and muscle-sparing benefits.<\/p> Cocoabuterol\u00ae supports muscle growth and muscle retention through supporting improved muscle protein synthesis, reduced muscle protein use, and improving adipose utilization.<\/p> Cocoabuterol\u00ae is unique in that it is stimulant free but is still associated with an increase in \u2018feel good\u2019 mental energy to help get you feeling more awake and mentally sharp. Also, being derived from chocolate, Cocoabuterol\u00ae supports an increase in positive mood to help you feel less stressed.<\/p> CaloriBurn GP\u00ae is a standardized extract of the Grains of Paradise seed, also known as Aframomum Melegueta, a spice native to West Africa that belongs to the same family as ginger. CaloriBurn GP\u00ae is ideal for those looking for improved body-composition and enhanced fat loss.<\/p> To understand how CaloriBurn GP\u00ae works, it is helping to under the different types of adipose tissue (fat) in the body:<\/p> White Adipose Tissue (WAT)\/White Fat Cells \u2013 are your body\u2019s energy storage cells; basically, they are the fat that your body stores as stored energy (leftover unburned calories from the food that you eat). Large amounts of white fat around the abdominal area is associated with a higher risk of metabolic disease.<\/p> Brown Adipose Tissue (BAT)\/Brown Fat Cells \u2013 are used for diet and cold induced thermogenesis (maintaining your body\u2019s normal temperature when exposed to cold). Brown fat generates heat by burning calories.<\/p> CaloriBurn GP\u00ae has the unique ability to help convert white fat to brown fat, thereby converting the energy storing fat tissue into the type of fat tissue that help helps increase thermogenesis and total calorie expenditure.<\/p> Unlike many fat loss ingredients, Grains of Paradise\/Aframomum is backed by human studies. One study showed that subjects had a significantly greater increase in energy expenditure, seemingly due to the increase in brown fat activity versus the placebo group.<\/p> Another study showed that subject (non-obese women) that consumed Grains of Paradise\/Aframomum had greater decreases in body-fat around the lower abdominals as well as lower levels of visceral fat in the same area as compared to those who consumed a placebo; and very significantly this was with both groups NOT making any changes in diet and exercise.<\/p> Gamma-butyrobetaine (GBB) is a precursor to L-Carnitine that has the ability to increase the body\u2019s production of L-Carnitine and help improve energy levels, fat loss, athletic performance, and more.<\/p> GBB is referred to by some as \u2018Super Carnitine\u2019 and functions similarly to other L-Carnitine supplements but at a dramatically lower dosage and takes things a step further due to its ability to raise plasma levels of L-Carnitine.<\/p> GBB can also help support thermogenesis as evidenced by the increased sweating that some feel when using GBB which has led some people to say that they \u2018feel the fat melting off\u2019. Of course, that is an exaggeration but is a good indication of the great fat burning results that many feel from GBB.<\/p> Caffeine Anhydrous is the staple ingredient in many fat loss and energy products and for good reason.<\/p> With numerous studies supporting Caffeine\u2019s role in fat loss, most notably through thermogenesis, Caffeine has also been shown to improve exercise performance and has a key role in increasing energy, mental focus, mood, cognitive ability, and has potential synergistic effects with other key ingredients in Lipo Elite.<\/p> Infinergy\u2122 DiCaffeine Malate is a form of Caffeine that has been bonded to Malic Acid which can both extend the effects of the caffeine and increase energy production through Malic Acid\u2019s role in the Krebs cycle. By combining the well-established properties of both Caffeine and Malic Acid, Infinergy\u2122 offers a multi-dimensional ingredient that not only optimizes energy levels but also stimulates thermogenesis while promoting mental focus.<\/p> N-Phenethyl-Dimethylamine is a very potent stimulant and fat burning ingredient that may offer potential mood-boosting effects through increasing dopamine and noradrenaline in the body. Dopamine is commonly referred to as the \u2018feel-good\u2019 hormone. These hormones also support improved concentration, alertness, mental focus, positive mood, and an improved sense of well-being.<\/p> In addition to its energy and fat burning benefits, common feedback on this ingredient includes improved mood and focus in the gym, during exercise, &\/or in day-to-day life.<\/p> Theobromine is a methylxanthine and is the \u2018feel good\u2019 ingredient in chocolate. The relaxed feeling that one experiences after chocolate consumption can be attributed to theobromine.<\/p> Some people get confused in comparing theobromine to caffeine. Theobromine is a methylxanthine and therefore chemically related to caffeine, but the effects are very different. Unlike caffeine, theobromine is not a central nervous system stimulant. Also, caffeine has two methyl groups whereas theobromine has three. The presence of the additional methyl group slows the clearance of theobromine from the body (longer half-life) and thus theobromine provides longer lasting energy than caffeine.<\/p> The energy from theobromine is commonly described as a sustained long lasting relaxed feel-good energy without a crash.<\/p> Synephrine is a naturally occurring substance found in plants that has been used for thousands of years in Traditional Chinese Medicine (TCM) and is found mainly in Citrus Aurantium\/Orange peels. Synephrine has been commonly used to help burn fat, suppress appetite, and increase energy. The energy from Synephrine is commonly described as a clean energy without the crash associated with some other stimulants.<\/p> It seems like with every day that goes by, most of us find ourselves leading increasingly stressful lives and stress is something that can take a toll on us, both emotionally and physically. Sustained levels of stress can be detrimental to both our physical and mental health. This can take a toll on our relationships, jobs, hobbies, and our appearance.<\/p> Whether it be from an actual increase in appetite, grabbing some comfort food, or being an emotional eater, many of us find that as our level of stress goes up, so does our appetite and food consumption.<\/p> KannaEase\u2122 is a high potency specialized Sceletium Tortuosum (Kanna) extract that is designed to support positive mood, relaxation, calmness, improved sense of well-being, and more.<\/p> KannaEase\u2122 is included in Lipo Elite to both help the energizing effects be smoother and without the crash associated with many stimulant-based fat burners and also to help keep your mind off of the stresses of day-to-day life and focused on your goals instead of on food.<\/p> AstraGin\u00ae is a natural patented ingredient complex comprised of highly fractionated Astragalus membranaceus and Panax notoginseng and created using pharmaceutical grade extraction and processing technology and designed to help enhance nutrient absorption.<\/p> In short, AstraGin\u00ae is designed to help make sure you properly absorb the other great nutrients in Lipo Elite for maximum results.<\/p> Bioperine\u00ae is a standardized extract from the fruit of Piper nigrum L (Black Pepper) containing 95% piperine. Piperine has been shown to enhance the oral bioavailability of many ingredients.<\/p> Bioperine\u00ae is included in Lipo Elite to be the perfect one-two punch with AstraGin\u00ae to help ensure that you properly absorb and get the maximum benefits out of all of the awesome ingredients in the comprehensive Lipo Elite formulation.<\/p> Stacking & Synergy: Lipo Elite can be stacked with LipoVantage, M-Test, Anabolic Effect, Epi-Plex, Super Swole, or a variety of other Competitive Edge Labs products to help you reach your individual goals.<\/p> *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, cure, prevent, or treat any disease.<\/p>","gtin12":"891192002374","image":["https:\/\/siteimgs.com\/10017\/item\/lip-elite-rendering-fro_1662477250-0.jpg"],"brand":"Competitive Edge Labs CEL","url":"https:\/\/www.dpsnutrition.net\/i\/32334\/competitive-edge-labs-lipo-elite-90-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"38.46","url":"https:\/\/www.dpsnutrition.net\/i\/32334\/competitive-edge-labs-lipo-elite-90-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Competitive Edge Labs LipoVantage Stimulant Free Fat Burner - 180 Capsule (2 x 90 Capsule Bottles) TWINPACK","sku":"CG2032","description":" Highlights\/Supports:<\/p> \r\n <\/p>\r\n 1,000 mg. MitoBurn<\/p>\r\n 250 mg. Hops (std. for Isohumulones)<\/p>\r\n 250 mg. SEA (Stearoylethanolamide)<\/p>\r\n 100 mg. OEA (Oleoylethanolamide)<\/p>\r\n 75 mg. CaloriBurn<\/p>\r\n 25 mg. AstraGin<\/p>\r\n 10 mg. Bioperine<\/p>\r\n <\/p>\r\n LipoVantage is an ultra-potent stimulant free fat burner and natural exercise mimetic that is designed to help you burn stubborn body-fat and get the maximum results out of your diet &\/or exercise regimen.<\/p>\r\n <\/p>\r\n ^^^ If you answered yes to any of these questions, LipoVantage may be right for you.<\/p>\r\n <\/p>\r\n LipoVantage is great for athletes trying to get to get the most out of their workouts, individuals trying to lose weight and amplify their diet and workouts, people looking to maintain lean muscle while losing fat, and by anyone who is looking to improve body-composition, get leaner, and be more fit.<\/p>\r\n LipoVantage can be used by both men and women.<\/p>\r\n LipoVantage isn’t just another fat burner thrown together with popular trendy ingredients to get a sale. As a matter of fact, even many supplement enthusiasts may be familiar with some of the super exciting ingredients that make LipoVantage so unique and so effective.<\/p>\r\n LipoVantage is a scientifically designed precision formulation of active ingredients that is not only designed to help you maximize fat loss through a variety of exciting pathways but to also help you retain lean muscle while doing it.<\/p>\r\n Here are just some of the ways that the ingredients in LipoVantage may help support your fat loss goals:<\/p>\r\n In the simplest terms, this applies to fat loss and the importance of a basic understanding of it will become more clear as you read through the ingredient descriptions below.<\/p>\r\n The Peroxisome Proliferator-Activated Receptor (PPAR) family is divided into three subgroups – alpha, delta\/beta, and gamma. PPARalpha is highly expressed in muscle, the liver, kidneys, and heart and is involved in the regulation of lipid metabolism, specifically the transcription of the genes involved in the beta-oxidation (burning) of fatty acids and lipogenesis (storage of fatty acids).<\/p>\r\n Fat can be oxidized in the mitochondria and peroxisomes of cells, with the majority of this oxidation occurring in skeletal muscle cells and the liver.<\/p>\r\n PPAR-alpha activation increases fat oxidation in the mitochondria and peroxisomes by increasing the expression of enzymes involved in beta-oxidation of fatty acids. In addition, PPAR-alpha activation also increased the number or peroxisomes and mitochondria. This combination of an increased number of peroxisomes and mitochondria plus the increase in beta-oxidation of fatty acids increases the rate and capacity at which fat can be burned.<\/p>\r\n In simple terms, the activation of PPAR-alpha would be very beneficial to those looking to burn fat.<\/p>\r\n MitoBurn® is a revolutionary fat incinerating ingredient.<\/p>\r\n BAIBA (β-aminoisobutyric acid) is an amino acid that can be found naturally in both plant and animal sources but that until now hasn’t been widely commercially available as a raw material ingredient due to the inability to keep it stable as a powder and procure it in its most biologically active type, L-BAIBA.<\/p>\r\n L-BAIBA, a metabolite of the amino acid L-Valine, is a powerful myokine (also known as ‘exercise factors’) and has the ability to stimulate certain ‘exercise factors’ that are released from skeletal muscle in response to muscular stress, especially muscle contraction.<\/p>\r\n L-BAIBA plays an important role in the benefits of regular exercise and is the starting point for a positive sequence of events including increased free fatty acid oxidization, improved glucose uptake, and reduced body fat.<\/p>\r\n L-BAIBA works through multiple pathways. The primary one is though initiating the ‘browning’ of white adipose (fat) tissue, which increases energy expenditure, improves insulin sensitivity, and helps regulate weight management. A very novel one is that it has also been shown to help decrease the ‘beiging’ of adipose tissue. This ‘beiging’ process is when the body reverses the preferred adipose tissue color of brown (high energy usage) back to white (high energy storage).<\/p>\r\n L-BAIBA levels are associated with many of exercise’s numerous benefits, including amplifying the fat burning effects of exercise so you see results faster.<\/p>\r\n MitoBurn® is the first clinically tested and verified form of L-BAIBA.<\/p>\r\n MitoBurn® (L-BAIBA) Highlights\/Supports:<\/span><\/strong><\/p>\r\n MitoBurn® (L-BAIBA) as a PPAR Activator:<\/strong><\/span><\/p>\r\n The significance of Peroxisome Proliferator-Activated Receptor (PPAR) activation is discussed in detail in a separate section of this write up. In simple terms, PPAR-alpha activation does a lot of the work that we desire for when exercising and trying to burn fat.<\/p>\r\n There is so much excitement about MitoBurn® as an exercise mimetic that many people often overlook that L-BAIBA is also a potent PPAR-alpha activator. This is one of the mechanisms through which L-BAIBA supports the browning of white adipose tissue and the increase in beta oxidation (the process in which fat is broken down for use as energy by the body) and decrease in fat creation<\/p>\r\n Hops is an herb that people tend to most commonly associate with relaxation and being one of the ingredients in beer. With Hops, as with many herbs, it’s not the herb itself that is most significant, it’s what the herb is standardized\/extracted for that makes the difference – in this case, Isohumulones.<\/p>\r\n Isohumulones (iso-α-acids) are a natural flavonoid found in hops and are the major bitter components in beer and come from the female hops plant (Humulus lupulus L.).<\/p>\r\n Isohumulones (iso-α-acids) have been shown to help obese individuals with prediabetes by supporting reducing hyperglycemia, the lowering of blood sugar, improved insulin sensitivity (decreased insulin resistance), and increased fat loss; thereby supporting improving some of the underlying markers of metabolic syndrome.<\/p>\r\n This exciting ingredient has been the subject of both rodent and human studies.<\/p>\r\n In a rodent study, Isohumulones (iso-α-acids) were shown to support a reduction in diet induced obesity. They were also shown to support the reduction of body-fat in rodents in part by increasing thermogenesis in brown adipose tissue. (Think – significance of the other ingredients in LipoVantage supporting the browning of white adipose tissue).<\/p>\r\n In one study on Isohumulones (iso-α-acids), healthy obese individuals had a significant reduction in visceral fat and total abdominal fat after 12 weeks as compared to a placebo. The reduction is visceral and total fat areas was approximately two-fold lower than in the placebo group.<\/p>\r\n Isohumulones have also been shown to support Peroxisome Proliferator-Activator Receptors (PPAR) activation.<\/p>\r\n Stearoylethanolamide (SEA) is a fatty acid amide and endocannabinoid neurotransmitter that has been shown to support a decrease in food intake (support appetite control) and support fat loss independent of the PPAR pathway.<\/p>\r\n In addition to its fat loss and appetite control support benefits, SEA may also have possible neuroprotective and anti-inflammatory benefits.<\/p>\r\n Oleoylethanolamide (OEA) is an exogenous lipid synthesized in the intestines that has been shown to have anorexic properties, meaning that it decreases food intake (supports appetite control).<\/p>\r\n OEA is also an activator of Peroxisome Proliferator-Activator Receptor Alpha (PPAR-alpha). Activation of PPAR-alpha supports an increase in fat oxidation (the breaking down of fatty acids) along with a decrease in fat storage, thereby creating an ideal environment for fat loss.<\/p>\r\n When speaking on OEA’s potential appetite control benefits, one sports dietician was quoted as saying that “Studies report that ODEA can turn off the switch in the central nervous system for hunger”.<\/p>\r\n In addition to its potent fat loss properties, OEA may also have potential anti-inflammatory benefits.<\/p>\r\n CaloriBurn GP® is a standardized extract of the Grains of Paradise seed, also known as Aframomum Melegueta, a spice native to West Africa that belongs to the same family as ginger. CaloriBurn GP® is ideal for those looking for improved body-composition and enhanced fat loss.<\/p>\r\n To understand how CaloriBurn GP® works, it is helping to under the different types of adipose tissue (fat) in the body:<\/p>\r\n CaloriBurn GP® has the unique ability to help convert white fat to brown fat, thereby converting the energy storing fat tissue into the type of fat tissue that help helps increase thermogenesis and total calorie expenditure.<\/p>\r\n Unlike many fat loss ingredients, Grains of Paradise\/Aframomum is backed by human studies. One study showed that subjects had a significantly greater increase in energy expenditure, seemingly due to the increase in brown fat activity versus the placebo group.<\/p>\r\n Another study showed that subject (non-obese women) that consumed Grains of Paradise\/Aframomum had greater decreases in body-fat around the lower abdominals as well as lower levels of visceral fat in the same area as compared to those who consumed a placebo; and very significantly this was with both groups NOT making any changes in diet and exercise.<\/p>\r\n AstraGin® is a natural patented ingredient complex comprised of highly fractionated Astragalus membranaceus and Panax notoginseng and created using pharmaceutical grade extraction and processing technology and designed to help enhance nutrient absorption.<\/p>\r\n In short, AstraGin® is designed to help make sure you properly absorb the other great nutrients in LipoVantage for maximum results.<\/p>\r\n Bioperine® is a standardized extract from the fruit of Piper nigrum L (Black Pepper) containing 95% piperine. Piperine has been shown to enhance the oral bioavailability of many ingredients.<\/p>\r\n Bioperine® is included in LipoVantage to be the perfect one-two punch with AstraGin® to help ensure that you properly absorb and get the maximum benefits out of all of the awesome ingredients in the comprehensive LipoVantage formulation.<\/p>\r\n LipoVantage can be stacked with CEL Lipo Elite, M-Test, Epi-Plex, Api-Plex, Anabolic Effect, or a variety of other Competitive Edge Labs products for improved synergistic results.<\/p>\r\n<\/div>","gtin12":"891192002404","image":["https:\/\/siteimgs.com\/10017\/item\/lipo-van2_1716647642-0.jpg"],"brand":"Competitive Edge Labs CEL","url":"https:\/\/www.dpsnutrition.net\/i\/34141\/competitive-edge-labs-lipovantage-180-cap-2-x-90.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"73.98","url":"https:\/\/www.dpsnutrition.net\/i\/34141\/competitive-edge-labs-lipovantage-180-cap-2-x-90.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Competitive Edge Labs LipoVantage Stimulant Free Fat Burner - 90 Capsules","sku":"CG032","description":" Highlights\/Supports:<\/p> 1,000 mg. MitoBurn 250 mg. Hops (std. for Isohumulones) 250 mg. SEA (Stearoylethanolamide) 100 mg. OEA (Oleoylethanolamide) 75 mg. CaloriBurn 25 mg. AstraGin 10 mg. Bioperine<\/p> LipoVantage is an ultra-potent stimulant free fat burner and natural exercise mimetic that is designed to help you burn stubborn body-fat and get the maximum results out of your diet &\/or exercise regimen.<\/p> ^^^ If you answered yes to any of these questions, LipoVantage may be right for you.<\/p> LipoVantage is great for athletes trying to get to get the most out of their workouts, individuals trying to lose weight and amplify their diet and workouts, people looking to maintain lean muscle while losing fat, and by anyone who is looking to improve body-composition, get leaner, and be more fit.<\/p> LipoVantage can be used by both men and women.<\/p> LipoVantage isn\u2019t just another fat burner thrown together with popular trendy ingredients to get a sale. As a matter of fact, even many supplement enthusiasts may be familiar with some of the super exciting ingredients that make LipoVantage so unique and so effective.<\/p> LipoVantage is a scientifically designed precision formulation of active ingredients that is not only designed to help you maximize fat loss through a variety of exciting pathways but to also help you retain lean muscle while doing it.<\/p> Here are just some of the ways that the ingredients in LipoVantage may help support your fat loss goals:<\/p> In the simplest terms, this applies to fat loss and the importance of a basic understanding of it will become more clear as you read through the ingredient descriptions below.<\/p> The Peroxisome Proliferator-Activated Receptor (PPAR) family is divided into three subgroups \u2013 alpha, delta\/beta, and gamma. PPARalpha is highly expressed in muscle, the liver, kidneys, and heart and is involved in the regulation of lipid metabolism, specifically the transcription of the genes involved in the beta-oxidation (burning) of fatty acids and lipogenesis (storage of fatty acids).<\/p> Fat can be oxidized in the mitochondria and peroxisomes of cells, with the majority of this oxidation occurring in skeletal muscle cells and the liver.<\/p> PPAR-alpha activation increases fat oxidation in the mitochondria and peroxisomes by increasing the expression of enzymes involved in beta-oxidation of fatty acids. In addition, PPAR-alpha activation also increased the number or peroxisomes and mitochondria. This combination of an increased number of peroxisomes and mitochondria plus the increase in beta-oxidation of fatty acids increases the rate and capacity at which fat can be burned.<\/p> In simple terms, the activation of PPAR-alpha would be very beneficial to those looking to burn fat.<\/p> MitoBurn\u00ae is a revolutionary fat incinerating ingredient.<\/p> BAIBA (\u03b2-aminoisobutyric acid) is an amino acid that can be found naturally in both plant and animal sources but that until now hasn\u2019t been widely commercially available as a raw material ingredient due to the inability to keep it stable as a powder and procure it in its most biologically active type, L-BAIBA.<\/p> L-BAIBA, a metabolite of the amino acid L-Valine, is a powerful myokine (also known as \u2018exercise factors\u2019) and has the ability to stimulate certain \u2018exercise factors\u2019 that are released from skeletal muscle in response to muscular stress, especially muscle contraction.<\/p> L-BAIBA plays an important role in the benefits of regular exercise and is the starting point for a positive sequence of events including increased free fatty acid oxidization, improved glucose uptake, and reduced body fat.<\/p> L-BAIBA works through multiple pathways. The primary one is though initiating the \u2018browning\u2019 of white adipose (fat) tissue, which increases energy expenditure, improves insulin sensitivity, and helps regulate weight management. A very novel one is that it has also been shown to help decrease the \u2018beiging\u2019 of adipose tissue. This \u2018beiging\u2019 process is when the body reverses the preferred adipose tissue color of brown (high energy usage) back to white (high energy storage).<\/p> L-BAIBA levels are associated with many of exercise\u2019s numerous benefits, including amplifying the fat burning effects of exercise so you see results faster. MitoBurn\u00ae is the first clinically tested and verified form of L-BAIBA.<\/p> The significance of Peroxisome Proliferator-Activated Receptor (PPAR) activation is discussed in detail in a separate section of this write up. In simple terms, PPAR-alpha activation does a lot of the work that we desire for when exercising and trying to burn fat.<\/p> There is so much excitement about MitoBurn\u00ae as an exercise mimetic that many people often overlook that L-BAIBA is also a potent PPAR-alpha activator. This is one of the mechanisms through which L-BAIBA supports the browning of white adipose tissue and the increase in beta oxidation (the process in which fat is broken down for use as energy by the body) and decrease in fat creation<\/p> Hops is an herb that people tend to most commonly associate with relaxation and being one of the ingredients in beer. With Hops, as with many herbs, it\u2019s not the herb itself that is most significant, it\u2019s what the herb is standardized\/extracted for that makes the difference \u2013 in this case, Isohumulones.<\/p> Isohumulones (iso-\u03b1-acids) are a natural flavonoid found in hops and are the major bitter components in beer and come from the female hops plant (Humulus lupulus L.).<\/p> Isohumulones (iso-\u03b1-acids) have been shown to help obese individuals with prediabetes by supporting reducing hyperglycemia, the lowering of blood sugar, improved insulin sensitivity (decreased insulin resistance), and increased fat loss; thereby supporting improving some of the underlying markers of metabolic syndrome.<\/p> This exciting ingredient has been the subject of both rodent and human studies.<\/p> In a rodent study, Isohumulones (iso-\u03b1-acids) were shown to support a reduction in diet induced obesity. They were also shown to support the reduction of body-fat in rodents in part by increasing thermogenesis in brown adipose tissue. (Think \u2013 significance of the other ingredients in LipoVantage supporting the browning of white adipose tissue).<\/p> In one study on Isohumulones (iso-\u03b1-acids), healthy obese individuals had a significant reduction in visceral fat and total abdominal fat after 12 weeks as compared to a placebo. The reduction is visceral and total fat areas was approximately two-fold lower than in the placebo group.<\/p> Isohumulones have also been shown to support Peroxisome Proliferator-Activator Receptors (PPAR) activation.<\/p> Stearoylethanolamide (SEA) is a fatty acid amide and endocannabinoid neurotransmitter that has been shown to support a decrease in food intake (support appetite control) and support fat loss independent of the PPAR pathway.<\/p> In addition to its fat loss and appetite control support benefits, SEA may also have possible neuroprotective and anti-inflammatory benefits.<\/p> Oleoylethanolamide (OEA) is an exogenous lipid synthesized in the intestines that has been shown to have anorexic properties, meaning that it decreases food intake (supports appetite control).<\/p> OEA is also an activator of Peroxisome Proliferator-Activator Receptor Alpha (PPAR-alpha). Activation of PPAR-alpha supports an increase in fat oxidation (the breaking down of fatty acids) along with a decrease in fat storage, thereby creating an ideal environment for fat loss.<\/p> When speaking on OEA\u2019s potential appetite control benefits, one sports dietician was quoted as saying that \u201cStudies report that ODEA can turn off the switch in the central nervous system for hunger\u201d.<\/p> In addition to its potent fat loss properties, OEA may also have potential anti-inflammatory benefits.<\/p> CaloriBurn GP\u00ae has the unique ability to help convert white fat to brown fat, thereby converting the energy storing fat tissue into the type of fat tissue that help helps increase thermogenesis and total calorie expenditure.<\/p> Unlike many fat loss ingredients, Grains of Paradise\/Aframomum is backed by human studies. One study showed that subjects had a significantly greater increase in energy expenditure, seemingly due to the increase in brown fat activity versus the placebo group.<\/p> Another study showed that subject (non-obese women) that consumed Grains of Paradise\/Aframomum had greater decreases in body-fat around the lower abdominals as well as lower levels of visceral fat in the same area as compared to those who consumed a placebo; and very significantly this was with both groups NOT making any changes in diet and exercise.<\/p> AstraGin\u00ae is a natural patented ingredient complex comprised of highly fractionated Astragalus membranaceus and Panax notoginseng and created using pharmaceutical grade extraction and processing technology and designed to help enhance nutrient absorption.<\/p> In short, AstraGin\u00ae is designed to help make sure you properly absorb the other great nutrients in LipoVantage for maximum results.<\/p> Bioperine\u00ae is a standardized extract from the fruit of Piper nigrum L (Black Pepper) containing 95% piperine. Piperine has been shown to enhance the oral bioavailability of many ingredients.<\/p> Bioperine\u00ae is included in LipoVantage to be the perfect one-two punch with AstraGin\u00ae to help ensure that you properly absorb and get the maximum benefits out of all of the awesome ingredients in the comprehensive LipoVantage formulation.<\/p> LipoVantage can be stacked with CEL Lipo Elite, M-Test, Epi-Plex, Api-Plex, Anabolic Effect, or a variety of other Competitive Edge Labs products for improved synergistic results.<\/p>","gtin12":"891192002404","image":["https:\/\/siteimgs.com\/10017\/item\/lipovantage-front-resized_1660941181-0.jpg"],"brand":"Competitive Edge Labs CEL","url":"https:\/\/www.dpsnutrition.net\/i\/32290\/competitive-edge-labs-lipovantage-90-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.99","url":"https:\/\/www.dpsnutrition.net\/i\/32290\/competitive-edge-labs-lipovantage-90-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Core Nutritionals SEAR - 84 Capsules Non-Stimulant Thermogenic and Recomposition Agent","sku":"CU295","description":" Why do we call it \u201cburning fat\u201d? It is a strange turn of phrase, as the body does not \u201cburn\u201d the adipose tissue (the technical name for \u201cfat\u201d). Of course, heat is involved in the base process of fat metabolism, hydrolysis, but the average person of course does not have these in mind. What the common phrasing captures is that the adipose tissue is now being used for fuel \u2013 burned up, as gasoline is burned up in a combustion engine as fuel for the vehicle. In this sense, the phrase \u201cburning fat\u201d captures something essential about the mechanisms of adipose metabolism. One mechanism of increasing this process overall is increasing the conversion of WAT (white adipose tissue) to BAT (brown adipose tissue) \u2013 known as the \u201cbrowning\u201d of fat.<\/p> It is precisely this mechanism that Core SEAR affects. There are many pathways to enhance lipolysis, the process by which stored triglycerides \u2013 the \u201cstuff\u201d of fat tissue \u2013 are broken down to release their potential energy into actual energy. One of the most effective is modulating the enzymes that interconvert WAT (white adipose tissue, which stores energy) to BAT (brown adipose tissue, which releases energy) and the chemical and enzymatic cascades that induce lipolysis. SEAR addresses both. Sinetrol XPur\u00ae, a blend of citrus fruit extracts, and MitoBurn\u2122, a metabolite of L-valine, have been demonstrated to increase white-to-brown adipose tissue conversion and therefore the resultant energy expenditure increase. Meanwhile, Coleus forskholli and Paradoxine\u00ae have been shown to heavily influence cellular communication and enzymatic pathways involved in lipolysis, specifically the cAMP and AMPk pathways.<\/p> Together, this simple but incredibly powerful formula earns its name: searing white into brown adipose tissue and increasing your body\u2019s energy expenditure due to fat metabolism.<\/p>","gtin12":"672975315597","image":["https:\/\/siteimgs.com\/10017\/item\/core-sear_1609864381-0.jpg"],"brand":"Core Nutritionals","url":"https:\/\/www.dpsnutrition.net\/i\/30481\/84-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"45.99","url":"https:\/\/www.dpsnutrition.net\/i\/30481\/84-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"EPG Oxy Xtreme - 2 x 60 Capsule Bottles TWINPACK","sku":"EPG27","description":" Stop wasting your money on those nasty energy drinks, and ineffective energy shots. Take a product that isn’t overloaded with caffeine, contains no chemicals and promotes a positive, creative energy with fat burning properties.<\/p>\r\n <\/p>\r\n FDA: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.<\/p>","image":["https:\/\/siteimgs.com\/10017\/item\/oxy-xtr2_1687805498-0.jpg"],"brand":"EPG Extreme Products","url":"https:\/\/www.dpsnutrition.net\/i\/18423\/epg-oxy-xtreme-twinpack-2-x-60-cap-bottles.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.99","url":"https:\/\/www.dpsnutrition.net\/i\/18423\/epg-oxy-xtreme-twinpack-2-x-60-cap-bottles.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"EPG Oxy Xtreme - 60 Capsules","sku":"EPG07","description":" Stop wasting your money on those nasty energy drinks, and ineffective energy shots. Take a product that isn’t overloaded with caffeine, contains no chemicals and promotes a positive, creative energy with fat burning properties.<\/p>\r\n <\/p>\r\n FDA: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.<\/p>","gtin12":"850002820898","image":["https:\/\/siteimgs.com\/10017\/item\/oxy-xtr1_1687805488-0.jpg"],"brand":"EPG Extreme Products","url":"https:\/\/www.dpsnutrition.net\/i\/18420\/epg-oxy-xtreme-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"21.99","url":"https:\/\/www.dpsnutrition.net\/i\/18420\/epg-oxy-xtreme-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"EvoMuse Abliterate AMMO - 2 x 60 Capsule Bottles TWINPACK","sku":"EM2052","description":" Abliderate AMMO Let\u2019s face it : the modern world sucks. Overstressed, overstimulated, and SO over it. A person can only take so much.<\/p> Abliderate AMMO was so cleverly named because its primary target is dominantly the Abdominal area, notably Visceral Adipose Tissue (VAT).<\/p> What is VAT? Well, an easy way to tell if you have a VAT problem is to put your hand on your abs and try to pull them in. Now, subcutaneous fat is the jiggly sufacen fat that on the outside of the abdominal wall that you can pinch. It is stubborn, harder to burn, and reacts mostly to lipolytics (see the Eviscerate series to best target that kind of fat.) Now, when you try to pull your abs in, if you can\u2019t pull them in very far, and your waist is still a bit larger than you want, with your abs protruding, you likely have a problem with VAT. Most people do. People that live in modern society anyway.<\/p> VAT is adipose (fat) that accumulates and surrounds your organs. It pushes out against your abdominal wall, increasing waist circumference and making you look more obese than you probably are. It is also deadly, causing most of the problems seen in the obese. It\u2019s mostly caused by a stress hormone called Cortisol, which is a destructive form of Cortisone (the hormone that makes your joints feel nice and smooth) that causes excess inflammation, muscle loss (catabolism), etc. The enzyme that causes cortison to convert to cortisol is called 11b Hydroxy Steroid Dehydrogenase (11b-HSD). Of the two \u201ctypes\u201d of this enzyme, type 1 is secreted by your fat cells in response to stress and alcohol intake. Yep...that protruding beer belly that is hard to the touch? That\u2019s why.<\/p> The good news? WE can easily suppress 11b-HSD, and once we do, VAT disappears very quickly as do the hyper-inflammatory adipokines. Something to remember, inflamed adipose tissue is resistant to normal metabolic processes and harder to burn. Now when I say quickly, provided you are making even the most basic attempt at burning, you should notice pretty dramatic effects within a week.<\/p> Abliderate AMMO is by far the most supreme VAT burning formula on the market.<\/p> Emodin-Cyclodextrin Complex<\/p> Emodin is an extemely potent and diverse compound. Its properties are widespread, and potent, but we\u2019ll only be covering a few.<\/p> Emodin\u2019s primary interest for us is its extremely potent 11b-HSD inhibiting properties, with an IC-50 (average dose to inhibit the enzyme to 50%) in the nanomolar range. This is usually in single digit milligram numbers, depending on the molecular weight. Emodin has pretty dismal oral absorption, so both the Cyclodextrin compex and the higher dosage ensures potency.<\/p> https:\/\/pubmed.ncbi.nlm.nih.gov\/20718744\/<\/p> Emodin also inhibits a form of Micro-RNA (miR-20) that modulates the central nervous system, and the related central fatigue and cortisol responses. As well, miR-20 inhibition restores glucose and insulin sensitivity in skeletal muscle, and allows SMAD7 (see the upcoming Slintensity writeup) to bolster differentiation of L6 myotubes to form new muscle cells\/fibers.<\/p> Finally, Emodin also reigns in Vascular Smooth Muscle Cell infiltration in the heart and surrounding vascular system to help control some cardiac diseases.<\/p> Magnolia (Magnolol and Honokiol) is another widely functional ingredient. In addition to inhibiting 11b-HSD<\/p> https:\/\/pubmed.ncbi.nlm.nih.gov\/8051615\/<\/p> Magnolia helps to inhibit the Aromatase enzyme, which robs us of our precious Testosterone and converting it into Estrogen. As well, the reduced Cortisol also helps to boost Testosterone. SPOILER: We like this.<\/p> Finally, Magnolia does something extraordinary to the Acetylcholine system of the brain (the acetyl groupn being something called an \u201cester\u201d). Magnolia not only reduces an enzyme called Acetylcholine Esterase (removes the esters), but boosts something called Acetylcholine Transferase, an enzyme that actually makes more Acetylcholine in the brain.<\/p> EK shares the starring role in this formula with Emodin. Besides also inhibiting 11b-HSD in nanomolar concentrations (while being MUCH cheaper than Emodin)<\/p> it is an incredible anti-inflammatory in Adipose tissue (subcutaneous and visceral). Inflamed fat cells are extremely resistant to lipolysis, and makes losing fat especially hard, as anyone with chronic obesity will tell you. Let them test out AMMO and they will see. Normalization of adipokines will allow the body to return to a more healthy state quickly.<\/p> Commonly known as Bitter Melon, chances are you\u2019ve seen this in other formulas. Normally used in Glucose Disposal Agents, it has many more functions we are tapping.<\/p> MC helps significantly to reduce post exercise HPA stress (which contributes to overtraining and CNS fatigue) and reduces markers of stress in skeletal muscle. Less stress, quicker recovery<\/p> MC also does significant reduction of BRAIN Cortisol levels, which again reduces HPA stress, improves mood, and reduces overall stress reactions<\/p> Finally we have ourselves an outlier function. You will read more about this when I release \u201cCRIT\u201d. MC has been show to reduce blood viscosity. By slightly thinning the blood, you reduce strain on the heart and vascular system.<\/p> Galangin is primarily found in the Alpinia Galangia herb, but is also strangely one of they key compounds found in Bee Propolis.<\/p> Galangin has been found to alleviate Lipid Dysregulation and inflammation, and appears to be more potent than Metformin.<\/p> While doing this, Galangin is surprisingly potent at inhibiting preadipocyte differentiation into mature adipocytes (lipogenesis and adipogenesis)<\/p> The final major ingredient is PhophatydilSerine. You will also read about this powerhouse in the CRIT writeup. As an essential component of every single cell membrane in the human body, PS not only helps membrane-bound receptors to function more smoothly, but reduces cortisol via a bit of a vague mechanism (an increases that beautiful Test:Cort ratio). It is highly active in the brain where it reduces stress on the HPA, improving mood and concentration and blunting CNS overtraining.<\/p> The last 2 ingredients, Zinc Gluconate and Vitamin C, both reduce cortisol but not at the powerhouse level, and reduce pro-oxidants and inflammation.<\/p> We are constantly bombarded by stress \u2013 some thrust upon us, some self-induced such as alcohol. Things are difficult enough keeping our bodies not only healthy, but attractive. Abliderate AMMO is extremely potent at reducing Cortisol, thus targeting that center mass fat we all hate, and keeping the stress from overwhelming our brains and bodies. Results are extremely quick.<\/p> Abliderate AMMO : Targeting Center Mass<\/p>","image":["https:\/\/siteimgs.com\/10017\/item\/ammo-twin_1675135884-0.jpg"],"brand":"EvoMuse","url":"https:\/\/www.dpsnutrition.net\/i\/32810\/evomuse-abliterate-ammo-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"68.79","url":"https:\/\/www.dpsnutrition.net\/i\/32810\/evomuse-abliterate-ammo-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"EvoMuse Abliterate AMMO - 60 Capsules","sku":"EM052","description":" Abliderate AMMO Let\u2019s face it : the modern world sucks. Overstressed, overstimulated, and SO over it. A person can only take so much.<\/p> Abliderate AMMO was so cleverly named because its primary target is dominantly the Abdominal area, notably Visceral Adipose Tissue (VAT).<\/p> What is VAT? Well, an easy way to tell if you have a VAT problem is to put your hand on your abs and try to pull them in. Now, subcutaneous fat is the jiggly sufacen fat that on the outside of the abdominal wall that you can pinch. It is stubborn, harder to burn, and reacts mostly to lipolytics (see the Eviscerate series to best target that kind of fat.) Now, when you try to pull your abs in, if you can\u2019t pull them in very far, and your waist is still a bit larger than you want, with your abs protruding, you likely have a problem with VAT. Most people do. People that live in modern society anyway.<\/p> VAT is adipose (fat) that accumulates and surrounds your organs. It pushes out against your abdominal wall, increasing waist circumference and making you look more obese than you probably are. It is also deadly, causing most of the problems seen in the obese. It\u2019s mostly caused by a stress hormone called Cortisol, which is a destructive form of Cortisone (the hormone that makes your joints feel nice and smooth) that causes excess inflammation, muscle loss (catabolism), etc. The enzyme that causes cortison to convert to cortisol is called 11b Hydroxy Steroid Dehydrogenase (11b-HSD). Of the two \u201ctypes\u201d of this enzyme, type 1 is secreted by your fat cells in response to stress and alcohol intake. Yep...that protruding beer belly that is hard to the touch? That\u2019s why.<\/p> The good news? WE can easily suppress 11b-HSD, and once we do, VAT disappears very quickly as do the hyper-inflammatory adipokines. Something to remember, inflamed adipose tissue is resistant to normal metabolic processes and harder to burn. Now when I say quickly, provided you are making even the most basic attempt at burning, you should notice pretty dramatic effects within a week.<\/p> Abliderate AMMO is by far the most supreme VAT burning formula on the market.<\/p> Emodin-Cyclodextrin Complex<\/p> Emodin is an extemely potent and diverse compound. Its properties are widespread, and potent, but we\u2019ll only be covering a few.<\/p> Emodin\u2019s primary interest for us is its extremely potent 11b-HSD inhibiting properties, with an IC-50 (average dose to inhibit the enzyme to 50%) in the nanomolar range. This is usually in single digit milligram numbers, depending on the molecular weight. Emodin has pretty dismal oral absorption, so both the Cyclodextrin compex and the higher dosage ensures potency.<\/p> https:\/\/pubmed.ncbi.nlm.nih.gov\/20718744\/<\/p> Emodin also inhibits a form of Micro-RNA (miR-20) that modulates the central nervous system, and the related central fatigue and cortisol responses. As well, miR-20 inhibition restores glucose and insulin sensitivity in skeletal muscle, and allows SMAD7 (see the upcoming Slintensity writeup) to bolster differentiation of L6 myotubes to form new muscle cells\/fibers.<\/p> Finally, Emodin also reigns in Vascular Smooth Muscle Cell infiltration in the heart and surrounding vascular system to help control some cardiac diseases.<\/p> Magnolia (Magnolol and Honokiol) is another widely functional ingredient. In addition to inhibiting 11b-HSD<\/p> https:\/\/pubmed.ncbi.nlm.nih.gov\/8051615\/<\/p> Magnolia helps to inhibit the Aromatase enzyme, which robs us of our precious Testosterone and converting it into Estrogen. As well, the reduced Cortisol also helps to boost Testosterone. SPOILER: We like this.<\/p> Finally, Magnolia does something extraordinary to the Acetylcholine system of the brain (the acetyl groupn being something called an \u201cester\u201d). Magnolia not only reduces an enzyme called Acetylcholine Esterase (removes the esters), but boosts something called Acetylcholine Transferase, an enzyme that actually makes more Acetylcholine in the brain.<\/p> EK shares the starring role in this formula with Emodin. Besides also inhibiting 11b-HSD in nanomolar concentrations (while being MUCH cheaper than Emodin)<\/p> it is an incredible anti-inflammatory in Adipose tissue (subcutaneous and visceral). Inflamed fat cells are extremely resistant to lipolysis, and makes losing fat especially hard, as anyone with chronic obesity will tell you. Let them test out AMMO and they will see. Normalization of adipokines will allow the body to return to a more healthy state quickly.<\/p> Commonly known as Bitter Melon, chances are you\u2019ve seen this in other formulas. Normally used in Glucose Disposal Agents, it has many more functions we are tapping.<\/p> MC helps significantly to reduce post exercise HPA stress (which contributes to overtraining and CNS fatigue) and reduces markers of stress in skeletal muscle. Less stress, quicker recovery<\/p> MC also does significant reduction of BRAIN Cortisol levels, which again reduces HPA stress, improves mood, and reduces overall stress reactions<\/p> Finally we have ourselves an outlier function. You will read more about this when I release \u201cCRIT\u201d. MC has been show to reduce blood viscosity. By slightly thinning the blood, you reduce strain on the heart and vascular system.<\/p> Galangin is primarily found in the Alpinia Galangia herb, but is also strangely one of they key compounds found in Bee Propolis.<\/p> Galangin has been found to alleviate Lipid Dysregulation and inflammation, and appears to be more potent than Metformin.<\/p> While doing this, Galangin is surprisingly potent at inhibiting preadipocyte differentiation into mature adipocytes (lipogenesis and adipogenesis)<\/p> The final major ingredient is PhophatydilSerine. You will also read about this powerhouse in the CRIT writeup. As an essential component of every single cell membrane in the human body, PS not only helps membrane-bound receptors to function more smoothly, but reduces cortisol via a bit of a vague mechanism (an increases that beautiful Test:Cort ratio). It is highly active in the brain where it reduces stress on the HPA, improving mood and concentration and blunting CNS overtraining.<\/p> The last 2 ingredients, Zinc Gluconate and Vitamin C, both reduce cortisol but not at the powerhouse level, and reduce pro-oxidants and inflammation.<\/p> We are constantly bombarded by stress \u2013 some thrust upon us, some self-induced such as alcohol. Things are difficult enough keeping our bodies not only healthy, but attractive. Abliderate AMMO is extremely potent at reducing Cortisol, thus targeting that center mass fat we all hate, and keeping the stress from overwhelming our brains and bodies. Results are extremely quick.<\/p> Abliderate AMMO : Targeting Center Mass<\/p>","gtin12":"752423448234","image":["https:\/\/siteimgs.com\/10017\/item\/ammo1_1675135950-0.jpg"],"brand":"EvoMuse","url":"https:\/\/www.dpsnutrition.net\/i\/32792\/evomuse-abliterate-ammo-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.99","url":"https:\/\/www.dpsnutrition.net\/i\/32792\/evomuse-abliterate-ammo-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"EvoMuse Brite Capsules - 180 Capsules *New Formula","sku":"EM036","description":" BRITE | Adipocyte Conversion Formula<\/p>\r\n \"A cold, starving animal doesn't care about a 6-pack.\"<\/p>\r\n Perspective is a complex thing. From the perspective of an undisciplined modern human, life is surrounded by plenty and our worries can consist of trying to reach our most aesthetically pleasing selves. However, perspective for most of the creatures on the planet is harsh, difficult, and a never-ending quest for precious resources.<\/p>\r\n Heat is one of the most precious resources, as the universe contends with \"hot spots\" in its quest to finally attain perfect order and energy distribution – namely heat death.<\/p>\r\n Nature, on the other hand – if it can be separated from the Universe – seems obsessed with continuing bright hot spots of life, without caring about individuals. The mechanistic viewpoint of our bodies, which still reigns supreme, follows laws of thermodynamics and thus life and heat can almost be interchangeable.<\/p>\r\n As we have covered countless times, humans, in our dominant but highly artificial state, are an aberration from the general rules. Nature drives numerous animals into dormancy when resources become scarce and more energy would be spent finding calories (heat, fuel) than could be replenished. Hibernation is the name of the game for Winter. Hibernation must be prepared for, which is why hibernating animals begin gorging and getting fat during Fall. Those fat stores are our point of interest, as much of it is stored in specialized cells.<\/p>\r\n The key to thermogenesis is adrenergic signaling (meaning related to adrenaline and noradrenaline). While humans have come to rely more on B2 (and A2) signaling for active lipolysis resulting in ATP formation with increases in heat a secondary effect (to fuel activity), the animals that hibernate during cold weather rely on different receptors (B3, A1) to generate heat via thermogenesis to go along with a more passive release of adrenaline\/noradrenaline, since for the most part they aren't moving much.<\/p>\r\n Human B3 receptors have lost importance, which means the first step is to increase activity here…<\/p>\r\n …but before we do that, let's take a quick step back for all those who are new to this here do-si-do.<\/p>\r\n A full decade ago, Evolutionary Muse released a first-in-kind product designed to facilitate the browning of white fat. Aptly named BRITE™, it shares the same name as those adipocytes which are named for being BROWN-IN-WHITE cells – white adipocytes which behave like brown adipocytes. Brown adipocytes are metabolically active cells which use their fat stores to generate body heat...the life hack of all life hacks, if you will. But there was one glaring problem – modern living was all but making this phenomenon a thing of the past. No problem, we should just reject modernity and embrace tradition. Right?<\/p>\r\n Wrong.<\/p>\r\n Evolutionary Muse: Inspire to Evolve. (Translation: We take a pill for that now.)<\/p>\r\n DIFFERENCE BETWEEN WAT AND BAT<\/p>\r\n BAT works quite differently, if not opposite, to White Adipose Tissue (WAT). BAT is dense in mitochondria and considered a highly thermogenic fat cell, responsible for creating heat through a process called “non-shivering thermogenesis”. This process burns calories through a futile cycle of shuttling protons to the mitochondria to generate heat. WAT, however, is what we all think of when we hear the term “body fat”. It stores calories so they can be used later during periods of hunger or famine, and secretes various adipokines.<\/p>\r\n Even more recently, we have discovered another player in the adipocyte story – Brown-in-White cells, or “BRITE”. At a microscopic level, these cells display a color between brown and white, and behave in a similar thermogenic fashion to BAT cells. While we don’t know yet if reduced thermogenic activity is a cause or consequence of obesity, we do know that an increase in BAT and\/or brite cells improves glucose tolerance and insulin sensitivity.<\/p>\r\n Two distinct pathways exist towards increasing brite cells in adult humans, (1) triggering precursor cells into becoming brite cells, and (2) turning mature WAT cells into brite cells. We want to target these pathways directly so that we can increase the ratio of brite cells to WAT cells, allowing your body to constantly burn more calories. So, let’s dive into some of the known methods of brite cell creation and activation.<\/p>\r\n COLD THERAPY, B3 ADRENERGIC ACTIVATORS<\/p>\r\n Cold exposure triggers macrophages in BAT to produce catecholamines like norepinephrine. Norepinephrine agonizes b-adrenergic receptors on fat cells. Cold also activates beige cell development and function. The effect can be mimicked with B3 adrenergic activators, which also trigger PGC-1a and brite cell development. It can also be mimicked with TRPM, or cold-sensor activators.<\/p>\r\n IRISIN AND PGC-1 ALPHA<\/p>\r\n Exercise causes increased expression in muscle of PPARg coactivator 1-alpha (PGC-1a), which downstream results in a hormone\/myokine called irisin. This irisin contributes to a browning of WAT cells. So not only does exercise burn calories directly, but also secondarily through triggering the browning process with irisin. Fortunately, this is an exploitable angle independent of exercise by triggering the PPARg cascade.<\/p>\r\n PRDM16, BMP-7<\/p>\r\n Prdm16 is a transcriptional cofactor, substantially enriched in human BAT compared to adjacent WAT. It acts by binding to and modulating other factors like C\/EBPb, PPARy, PPARa, and the aforementioned PGC-1a. Knocking out Prdm16 negates the thermogenic effect of brown cells, and increases WAT. Considered a key driver of brown fat cell fate, this cofactor is quite important. Bone Morphogenetic Protein-7 (BMP-7) increases expression of Prdm16 in precursor cells, and is essential for brown fat development. BMP-7 is fortunately something we can target with supplementation.<\/p>\r\n ADENYLYL CYCLASE AND ALPHA-1 ADRENERGIC ACTIVATION<\/p>\r\n Adenylyl cyclase is an enzyme that catalyzes the conversion of ATP to cyclic AMP. We mentioned beta-adrenergic receptor agonism, but it turns out this is greatly enhanced with simultaneous adenylyl cyclase upregulation and alpha-1 activation. So, targeting adenylyl cyclase, alpha-1, and beta-adrenergic agonism together causes enhanced brite cell creation.<\/p>\r\n UCP1<\/p>\r\n BAT mitochondria respond to something called UCP1 (uncoupling protein 1) to burn fat and generate heat, while brite cells seem to express lower levels of UCP1. However, brite cells potentially burn fat independently of UCP1 signaling, and furthermore, with the proper triggers, brite fat can actually turn on high levels of UCP1. Multiple ingredients in the BRITE formula will encourage WAT cells to upregulate UCP1 levels. Some of you may be familiar with a somewhat popular drug in the bodybuilding community years ago called DNP (which actually has roots in the 1930s as a weight loss drug). DNP was meant to mimic activated UCP1, which drastically elevated thermogenesis. While extremely effective, unregulated uncoupling can (and did) cause hyperthermia and death. Fortunately, we now have effective ways of targeting UCP1 safely.<\/p>\r\n PHOSPHODIESTERASES<\/p>\r\n Phosphodiesterases (or PDEs from here on out) are a family of enzymes that catalyze the inactivity (and therefore homeostasis) of the cAMP and\/or cGMP systems. An example we should all be familiar with is PDE5, which reduces cGMP in the erectile tissues, suppressing erectile response. Viagra, Cialis, etc., all inhibit the PDE5 enzyme, which leads to accumulation of cGMP, relaxation of penile tissues, dilation of blood vessels and eventually an erection.<\/p>\r\n The cAMP and cGMP systems are tightly controlled by physiological signals in order to maximally preserve resources. The cAMP system, for example, is related to energy states using Adenosine as a backbone (think highly depleted ATP – Adenosine Triphosphate). Elevation of cAMP leads to lipolysis, the freeing of fatty acids for transport to metabolically active tissue for either conversion to ATP or, in our case, thermogenesis.<\/p>\r\n There are two members of the PDE family that are of interest to us. One is PDE3b, the enzyme form activated by insulin to suppress lipolysis, allowing for the opposite to occur (storage of fat\/carbs). By suppressing PDE3b, we preserve a state of lipolysis and fat continues to be \"burned\" even after eating. Inhibition of PDE3b also removes the barriers of induction of UCP1, which causes non-shivering thermogenesis (the use of fatty acids to generate heat).<\/p>\r\n The other member is a newer player, PDE4D. Working hand-in-hand with PDE3b inhibition, PDE4D inhibition amplifies adrenergic signaling, UCP1 expression, lipolysis, and amplification of thermogenesis – especially basal (baseline) levels which means the rate of lipolysis without additional stimulation. The higher the basal rate, the more fat burned\/heat generated.<\/p>\r\n At the end of this inhibition, we go back to that Adenylyl Cyclase (and in the case of cGMP, Guanylyl Cyclase) creating the energy usage and replenishment cycle.<\/p>\r\n INGREDIENTS AND FUNCTION<\/p>\r\n Butcher’s Broom 50:1 Extract<\/p>\r\n Butcher’s Broom is a herb also known as Ruscus aculeatus. It gets its name from the practice of butchers using it for its supposed antibacterial properties to clean their cutting boards. It has been used in traditional medicine for its vasoconstrictive and anti-inflammatory actions (reducing swelling, preventing hemorrhoids, etc.).<\/p>\r\n The plant contains a variety of saponins, which have been shown to activate alpha-1 adrenergic receptors and stimulate the release of norepinephrine. It also has a protective effect on capillaries, strengthens blood vessels, and helps maintain healthy circulation.<\/p>\r\n As discussed previously, this alpha-1 activation is important and has been shown to shift preadipocytes to beige cells as opposed to white adipose tissue. As well, recent research shows that when hibernating, animals’ thermosensitive mechanisms will detect ambient and body temperatures and, if falling under threshold, the SNS will release norepinephrine to activate BAT in order to maintain viable body temperatures.<\/p>\r\n Gypenosides (75%)<\/p>\r\n Gypenosides are saponins found in the jiaogulan plant. This ingredient targets both WAT and BAT. With it we get WAT browning and an increase in fat oxidation genes in both WAT and BAT. Obesogenic diet mice treated with Gypenosides had a significantly reduced bodyweight vs. control, with lower cholesterol and insulin resistance. Gypenosides potently activate AMPk, which is tied directly to the cGMP\/cAMP systems and sympathetic\/parasympathetic nervous systems (metabolic autopilots), and amplify the lipolytic\/thermogenic effects on brite cells.<\/p>\r\n Menthol Crystals<\/p>\r\n Aside from B3 adrenergic receptor activation, the other most important way to start the browning process of WAT browning, as previously discussed, is through cold exposure. By exposing the body to cold temperatures long-term, it activates the TRPM8 receptor, which triggers browning in order to more effectively use WAT to create body warmth.<\/p>\r\n TRPM8 activation also enhances the thermogenic function of brown adipocytes through UCP1 and the b-adrenergic pathway.<\/p>\r\n So Menthol mimics long-term cold exposure by activating the TRPM8 channel, which has been shown to induce WAT browning as well as an upregulation in BAT thermogenesis. This has been shown to increase core temperature, reduce body fat and improve glucose metabolism.<\/p>\r\n Vanillin<\/p>\r\n An ingredient used in fake vanilla extracts for baking, Vanillin (and its metabolite Vanillic Acid) are metabolic derivatives from Anthocyanins. In addition to favorably reducing the ratio of Firmicutes to Bacteroides, resulting in a favorable gut environment for fat loss, Vanillin potently induces both browning of white fat and expression of UCP1.<\/p>\r\n Vanillin also increases glucose uptake in muscle tissue as well as regulating redox imbalances and inflammation.<\/p>\r\n Black Pepper Extract (20% Piperine)<\/p>\r\n TRPV1 is a capsaicin and vanilloid receptor in the body that is responsible for detection and regulation of body temperature and pain. More recently this receptor has been identified as a major player in obesity and body fat regulation. Stimulation of TRPV1 has been shown to upregulate BAT and increase fat oxidation and energy expenditure. TRPA1 is a similar receptor that functions to recognize cold and pain. Piperine, as well as several other compounds in black pepper, have been shown to be TRPV1 and TRPA1 agonists, with an even greater efficacy than capsaicin.<\/p>\r\n Trans-Cinnamaldehyde<\/p>\r\n Trans-Cinnamaldehyde is a pungent compound from cinnamon or dried cassia bark. It has been shown to increase UCP1 in both WAT and BAT, inducing browning of WAT cells. It also activates the cold receptor TRPA1. Back to those rodents fed obesogenic diets, Trans-Cinnamaldehyde inhibited hypertrophy of adipose cells, decreased body fat (including visceral fat), decreased voluntary food intake, and improved insulin sensitivity.<\/p>\r\n Salvia Miltiorrhiza 20:1 (Ethanol Extract)<\/p>\r\n Salvia Miltiorrhiza is a fascinating plant containing potent compounds that inhibit an enzyme called DGAT (diacylglycerol acyltransferase). Salvia Miltiorrhiza is able to prevent the final step in esterifying lipids into the form that WAT need them in – namely triacylglycerides (triglycerides). This keeps the lipids circulating in the bloodstream to be picked up and used by peroxisomes and mitochondria, and thrown off as heat.<\/p>\r\n Salvia Miltiorrhiza also inhibits SMAD2\/3 expression (see the BMP writeup), which suppresses myostatin activity and preserves muscle mass.<\/p>\r\n Salvia Miltiorrhiza has a dramatic effect on mitochondrial function in brite cells, basically turbocharging their activity by amplifying UCP1 activity.<\/p>\r\n Rutaecarpine<\/p>\r\n Contained in large quantities in the evodia fruit, it was first thought the Evodiamine was the compound responsible for the increase in non-shivering thermogenesis. Evodiamine turned out to be a huge disappointment, because it turns out the Rutaecarpine was what we were looking for.<\/p>\r\n Potently activating both AMPk and PGC-1a, Rutaecarpine also very strongly increases thermogenesis as well as mitochondrial biogenesis in brite cells. The more mitochondria, the more uncoupling and thus more thermogenesis and more fat burned.<\/p>\r\n Rutaecarpine also inhibits adipogenesis and lipogenesis, preventing lipid accumulation in WAT. Remember lipids in WAT have to be removed through a process of lipolysis before they can be transferred to metabolically active tissue and organelles (peroxisomes, mitochondria). By preventing WAT from accumulating lipids as well as crippling the body’s ability to simply make more white fat cells, all while shutting the lipids into the metabolically active brown\/brite fat cells, the process of thermogenesis becomes more efficient.<\/p>\r\n Sesamol<\/p>\r\n Sesamol is a phenol derivative of sesame oil with antioxidant and anti-inflammatory properties. This is another ingredient in the formula with the aforementioned two-pronged attack. It downregulates adipogenic differentiation factors (C\/EBPa, PPARy, SREBP-1) and decreases fat accumulating enzymes like fatty acid synthase (FAS), while upregulating fat oxidizing enzymes like HSL, LPL and AMPk. In mice on an obesogenic diet, it decreased fat mass and adipocyte size in both WAT and BAT by increasing UCP1 and PCG-1a.<\/p>\r\n Borneol<\/p>\r\n Borneol is a very potent P-glycoprotein efflux pump inhibitor. While “distracting” the P-gp pump, the ingredients of BRITE are able to enter the body unhindered by this physiochemical saboteur. As an additional benefit, Borneol also activates the TRPM8 cold receptor.<\/p>\r\n Myricetin-Nicotinamide Crystalline Complex<\/p>\r\n The primary superstar of the new formula, Myricetin is an incredibly diverse and hugely potent ingredient.<\/p>\r\n Let’s do a quick functional run through.<\/p>\r\n GLP-1 agonist – GLP-1 agonists are all the rage for weight loss right now. GLP-1 stands for Glucagon-like Peptide 1. Initially targeted to reverse type 2 diabetes, GLP-1 agonists soon manifested an interesting secondary effect – massive and rapid fat loss. As research gains traction, several explanations are emerging. A potent appetite suppression pathway, GLP-1 appears to be extremely active in the brain, activating brain-specific AMPk (hypothalamus, etc.) and stimulating central activation of brown\/brite fat thermogenesis. They also are highly active in increasing muscle-specific glucose uptake, and are effective at improving cardiac function. GLP-1 agonists are inactivated by something called dipeptidyl peptidase-4 (DPP-4). Interestingly enough, Myricetin inhibits DPP-4, thus amplifying and prolonging its own effect.<\/p>\r\n Myricetin has also been shown to be incredibly potent at inducing brite cell conversion, activating non-shivering thermogenesis, and dramatically increasing mitochondrial biogenesis (formation of new mitochondria).<\/p>\r\n GSK3b – Touched on briefly in the TopMuscle writeup, Glycogen Synthase Kinase 3b functions to inhibit a ton of growth associated positive effects in the body. This includes muscle growth, glycogen formation, and most importantly, brown\/brite fat thermogenesis. In fact, its potency at shutting down non-shivering thermogenesis is stunning. As luck (or design) would have it, Myricetin is the most potent GSK3b inhibitor so far found in natural form, with an IC50 of 900 nanomoles – incredibly potent.<\/p>\r\n PDE3b – as mentioned elsewhere, in order for BAT\/BRITE thermogenesis to be maximized, both PDE3b and PDE4D need to be inhibited. As if Myricetin hasn’t already shown to be badass, it also inhibits PDE3b.<\/p>\r\n Myricetin sounds great – let’s toss that in. Well, being a flavonoid, Myricetin has one of the worst oral absorption profiles I’ve ever seen, at very low single digit %. Other absorption enhancing methods (cyclodextrin, etc.) also turned out to be disappointing. However, I worked out a crystallization process with Nicotinamide that yielded some absolutely gorgeous, and highly absorbable, crystals – enabling us to include this spectacular ingredient in the formula.<\/p>\r\n The best part? Nicotinamide is also a highly potent brown fat activating ingredient, by both amplifying adrenergic signaling at the B3 receptor and by triggering mitochondrial biogenesis, as well as increasing expression of PPARa and PGC-1a.<\/p>\r\n Fucoxanthin 40%<\/p>\r\n Fucoxanthin is a simple ingredient. It dramatically increases expression of UCP1, which should be clear by now.<\/p>\r\n Ginger-6 Specialized Extract (std for 6-Paradol, 6-Shogaol, 6-Gingerol)<\/p>\r\n Ginger is absolutely one of the most popular plants for digestion, soothing a dysfunctional stomach, and tossing back after sushi and wasabi. It is also popular for fat loss, though in previous usages sort of haphazardly tossed in. I’m sure you’ve also seen something called Grains of Paradise (6-Paradol) used in competing formulas, though with highly mixed, often disappointing results. Turns out, if you know the correct solvents to use and in what order, you can extract the 3 main “browning” compounds from Ginger in high concentrations.<\/p>\r\n 6-Paradol – As mentioned it has become a commonly used ingredient. Another compound used to increase WAT browning, 6-Paradol also increases expression of PCG-1a and UCP1, resulting in increased thermogenesis with measurable temperature increases in brite\/brown adipose. However, of the three it appears to be the weakest.<\/p>\r\n 6-Shogaol – The immediate precursor of 6-Paradol, 6-Shogaol shows extreme promise as a thermogenic and browning agent, both in mature and preadipocytes. Increasing expression of the usual suspects (PCG-1a, UCP1), 6-Shogaol also increases mitochondrial turnover and biogenesis, increases the binding energy of ligands in the essential B3 adrenoreceptors (amplified signaling), and provides for a dramatic upregulation of beige markers, indicating significant browning of WAT.<\/p>\r\n 6-Gingerol – Along with 6-Shogaol, the most dominant compound in ginger – and the most potent. Sharing functionality with 6-Shogaol (all pathways similarly, but more potently, activated), 6-Gingerol also inhibits lipogenesis. 6-Gingerol also shows an extremely potent ability to break the giant lipid droplet which characterizes WAT into smaller, multiple droplets – enabling the shift to classical brite characteristics more easily.<\/p>\r\n Humulus Japonicus Extract 50:1 (Water)<\/p>\r\n Humulus Japonicus Extract is a new and exciting addition to the formula. In addition to inducing browning of WAT, it exerts potent antioxidant effects and increases expression of both AMPk and UCP1, as well as being a decent PPAR-delta agonist. The difference in hibernating animals using more PPARa to provide mitochondrial substrate in the liver is that they generally spend the winter dormant, whereas humans have the added benefit of physical motion, thus adding PPAR-delta, which is dominant in skeletal muscle, to the mix.<\/p>\r\n Quercetin-Theobromine Crystalline Complex<\/p>\r\n An absolute thermonuclear addition to the new formula is an ingredient combination I’ve been trying to fit for years, and this is an incredibly fortuitous (that means lucky) addition. Though they are grown together into a crystalline complex, which mostly enhances absorption by several fold, we will take each ingredient separately.<\/p>\r\n Quercetin – The Big Q is an extremely common compound in most plants. In addition to acting as a potent zinc ionophore (escort molecule into the cells), it is quite the potent antioxidant. But let’s get to the good stuff…<\/p>\r\n A 2021 study showed Quercetin to do a whole host of things related to BAT\/brite activation. It increases expression of PGC-1a (necessary for brite conversion) and UCP1, reduces plasma cholesterol, increases expression of the elusive (in humans) B3 adrenoreceptor (which is a key in the whole package), and as well induces mitochondrial transcription factors. Best of all? It was also discovered to be a very potent PDE4D inhibitor (see the section on phosphodiesterases\/cAMP) and, less potently, a PDE3b inhibitor. Recall that both PDE3b inhibition and PDE4D inhibition are required for both browning and optimized non-shivering thermogenesis.<\/p>\r\n As a side note, Quercetin decreases Firmicutes (starts with F for Fatty) to Bacteroides ratio in the gut, thus leading to a leaner phenotype expression.<\/p>\r\n Now Quercetin, while relatively inexpensive, has horrible solubility in water and dismal oral absorption. The crystallization with Theobromine increases oral absorption substantially.<\/p>\r\n Theobromine – Starting where we left off with Quercetin, Theobromine is ALSO quite a potent PDE4D inhibitor, the combination pretty much providing everything we need to preserve SNS cAMP signaling and optimized thermogenesis. But wait...there’s more!<\/p>\r\n Theobromine is a major component of cocoa. It has been toyed with, mostly unsuccessfully, in fat burning formulas for decades. Knowing what we know now about mechanisms, it makes sense why it didn’t deliver as promised.<\/p>\r\n Theobromine increases non-shivering thermogenesis, increases expression of PGC-1a, UCP1, other brite specific markers (we won’t be delving into those here quite yet) as well as increasing transport molecules like CPT1, which escorts shortened fatty acids from peroxisomes into the mitochondria for further beta-oxidation (and in our case, uncoupling\/heat production rather than ATP yield). In addition, Theobromine activates both B3 adrenoreceptors and AMPk, with the end result being a backblast of thermogenesis. As well, Theobromine suppresses preadipocyte differentiation, lipogenesis, and extends the browning effect to sub-mature adipocytes.<\/p>\r\n Oleuropein 50%<\/p>\r\n Oleuropein, contained in the olive plant, appears to be one of the main compounds contributing to the healthiness of the Mediterranean Diet. A unique compound, Oleuropein both dramatically increases UCP1 expression, and increases adrenaline\/noradrenaline secretion (absolutely essential for any kind of lipolysis, and therefore thermogenesis). Adrenaline\/noradrenaline acts as a ligand at the B3 adrenoreceptor (which, if you have been following has had both quantity increased as well as binding increased and signal amplified), the end result being hyperactivation of non-shivering thermogenesis.<\/p>\r\n We mentioned BMP7 also being essential to brown\/brite thermogenesis. While we are using a 50% oleuropein extract here, the other polyphenols in Olive (the “other” 50%) have been demonstrated to increase expression of BMP7, thus completing the perfection of our formula.<\/p>\r\n CONCLUSION<\/p>\r\n As you can see, we have exhaustively targeted all of the known pathways of creating and activating brite cells in the body through either recruiting precursor cells or converting mature white cells. Regular supplementation should encourage fat loss and mimicking of a lean phenotype acutely, and even more so when taken chronically – as brite cells don’t immediately revert back to white adipose upon cessation of the product. BRITE is a long-term solution to an ongoing, serious problem plaguing modern society.<\/p>\r\n <\/p>\r\n BRITE | Adipocyte Conversion Formula<\/p>\r\n \"A cold, starving animal doesn't care about a 6-pack.\"<\/p>\r\n Perspective is a complex thing. From the perspective of an undisciplined modern human, life is surrounded by plenty and our worries can consist of trying to reach our most aesthetically pleasing selves. However, perspective for most of the creatures on the planet is harsh, difficult, and a never-ending quest for precious resources.<\/p>\r\n Heat is one of the most precious resources, as the universe contends with \"hot spots\" in its quest to finally attain perfect order and energy distribution – namely heat death.<\/p>\r\n Nature, on the other hand – if it can be separated from the Universe – seems obsessed with continuing bright hot spots of life, without caring about individuals. The mechanistic viewpoint of our bodies, which still reigns supreme, follows laws of thermodynamics and thus life and heat can almost be interchangeable.<\/p>\r\n As we have covered countless times, humans, in our dominant but highly artificial state, are an aberration from the general rules. Nature drives numerous animals into dormancy when resources become scarce and more energy would be spent finding calories (heat, fuel) than could be replenished. Hibernation is the name of the game for Winter. Hibernation must be prepared for, which is why hibernating animals begin gorging and getting fat during Fall. Those fat stores are our point of interest, as much of it is stored in specialized cells.<\/p>\r\n The key to thermogenesis is adrenergic signaling (meaning related to adrenaline and noradrenaline). While humans have come to rely more on B2 (and A2) signaling for active lipolysis resulting in ATP formation with increases in heat a secondary effect (to fuel activity), the animals that hibernate during cold weather rely on different receptors (B3, A1) to generate heat via thermogenesis to go along with a more passive release of adrenaline\/noradrenaline, since for the most part they aren't moving much.<\/p>\r\n Human B3 receptors have lost importance, which means the first step is to increase activity here…<\/p>\r\n …but before we do that, let's take a quick step back for all those who are new to this here do-si-do.<\/p>\r\n A full decade ago, Evolutionary Muse released a first-in-kind product designed to facilitate the browning of white fat. Aptly named BRITE™, it shares the same name as those adipocytes which are named for being BROWN-IN-WHITE cells – white adipocytes which behave like brown adipocytes. Brown adipocytes are metabolically active cells which use their fat stores to generate body heat...the life hack of all life hacks, if you will. But there was one glaring problem – modern living was all but making this phenomenon a thing of the past. No problem, we should just reject modernity and embrace tradition. Right?<\/p>\r\n Wrong.<\/p>\r\n Evolutionary Muse: Inspire to Evolve. (Translation: We take a pill for that now.)<\/p>\r\n DIFFERENCE BETWEEN WAT AND BAT<\/p>\r\n BAT works quite differently, if not opposite, to White Adipose Tissue (WAT). BAT is dense in mitochondria and considered a highly thermogenic fat cell, responsible for creating heat through a process called “non-shivering thermogenesis”. This process burns calories through a futile cycle of shuttling protons to the mitochondria to generate heat. WAT, however, is what we all think of when we hear the term “body fat”. It stores calories so they can be used later during periods of hunger or famine, and secretes various adipokines.<\/p>\r\n Even more recently, we have discovered another player in the adipocyte story – Brown-in-White cells, or “BRITE”. At a microscopic level, these cells display a color between brown and white, and behave in a similar thermogenic fashion to BAT cells. While we don’t know yet if reduced thermogenic activity is a cause or consequence of obesity, we do know that an increase in BAT and\/or brite cells improves glucose tolerance and insulin sensitivity.<\/p>\r\n Two distinct pathways exist towards increasing brite cells in adult humans, (1) triggering precursor cells into becoming brite cells, and (2) turning mature WAT cells into brite cells. We want to target these pathways directly so that we can increase the ratio of brite cells to WAT cells, allowing your body to constantly burn more calories. So, let’s dive into some of the known methods of brite cell creation and activation.<\/p>\r\n COLD THERAPY, B3 ADRENERGIC ACTIVATORS<\/p>\r\n Cold exposure triggers macrophages in BAT to produce catecholamines like norepinephrine. Norepinephrine agonizes b-adrenergic receptors on fat cells. Cold also activates beige cell development and function. The effect can be mimicked with B3 adrenergic activators, which also trigger PGC-1a and brite cell development. It can also be mimicked with TRPM, or cold-sensor activators.<\/p>\r\n IRISIN AND PGC-1 ALPHA<\/p>\r\n Exercise causes increased expression in muscle of PPARg coactivator 1-alpha (PGC-1a), which downstream results in a hormone\/myokine called irisin. This irisin contributes to a browning of WAT cells. So not only does exercise burn calories directly, but also secondarily through triggering the browning process with irisin. Fortunately, this is an exploitable angle independent of exercise by triggering the PPARg cascade.<\/p>\r\n PRDM16, BMP-7<\/p>\r\n Prdm16 is a transcriptional cofactor, substantially enriched in human BAT compared to adjacent WAT. It acts by binding to and modulating other factors like C\/EBPb, PPARy, PPARa, and the aforementioned PGC-1a. Knocking out Prdm16 negates the thermogenic effect of brown cells, and increases WAT. Considered a key driver of brown fat cell fate, this cofactor is quite important. Bone Morphogenetic Protein-7 (BMP-7) increases expression of Prdm16 in precursor cells, and is essential for brown fat development. BMP-7 is fortunately something we can target with supplementation.<\/p>\r\n ADENYLYL CYCLASE AND ALPHA-1 ADRENERGIC ACTIVATION<\/p>\r\n Adenylyl cyclase is an enzyme that catalyzes the conversion of ATP to cyclic AMP. We mentioned beta-adrenergic receptor agonism, but it turns out this is greatly enhanced with simultaneous adenylyl cyclase upregulation and alpha-1 activation. So, targeting adenylyl cyclase, alpha-1, and beta-adrenergic agonism together causes enhanced brite cell creation.<\/p>\r\n UCP1<\/p>\r\n BAT mitochondria respond to something called UCP1 (uncoupling protein 1) to burn fat and generate heat, while brite cells seem to express lower levels of UCP1. However, brite cells potentially burn fat independently of UCP1 signaling, and furthermore, with the proper triggers, brite fat can actually turn on high levels of UCP1. Multiple ingredients in the BRITE formula will encourage WAT cells to upregulate UCP1 levels. Some of you may be familiar with a somewhat popular drug in the bodybuilding community years ago called DNP (which actually has roots in the 1930s as a weight loss drug). DNP was meant to mimic activated UCP1, which drastically elevated thermogenesis. While extremely effective, unregulated uncoupling can (and did) cause hyperthermia and death. Fortunately, we now have effective ways of targeting UCP1 safely.<\/p>\r\n PHOSPHODIESTERASES<\/p>\r\n Phosphodiesterases (or PDEs from here on out) are a family of enzymes that catalyze the inactivity (and therefore homeostasis) of the cAMP and\/or cGMP systems. An example we should all be familiar with is PDE5, which reduces cGMP in the erectile tissues, suppressing erectile response. Viagra, Cialis, etc., all inhibit the PDE5 enzyme, which leads to accumulation of cGMP, relaxation of penile tissues, dilation of blood vessels and eventually an erection.<\/p>\r\n The cAMP and cGMP systems are tightly controlled by physiological signals in order to maximally preserve resources. The cAMP system, for example, is related to energy states using Adenosine as a backbone (think highly depleted ATP – Adenosine Triphosphate). Elevation of cAMP leads to lipolysis, the freeing of fatty acids for transport to metabolically active tissue for either conversion to ATP or, in our case, thermogenesis.<\/p>\r\n There are two members of the PDE family that are of interest to us. One is PDE3b, the enzyme form activated by insulin to suppress lipolysis, allowing for the opposite to occur (storage of fat\/carbs). By suppressing PDE3b, we preserve a state of lipolysis and fat continues to be \"burned\" even after eating. Inhibition of PDE3b also removes the barriers of induction of UCP1, which causes non-shivering thermogenesis (the use of fatty acids to generate heat).<\/p>\r\n The other member is a newer player, PDE4D. Working hand-in-hand with PDE3b inhibition, PDE4D inhibition amplifies adrenergic signaling, UCP1 expression, lipolysis, and amplification of thermogenesis – especially basal (baseline) levels which means the rate of lipolysis without additional stimulation. The higher the basal rate, the more fat burned\/heat generated.<\/p>\r\n At the end of this inhibition, we go back to that Adenylyl Cyclase (and in the case of cGMP, Guanylyl Cyclase) creating the energy usage and replenishment cycle.<\/p>\r\n INGREDIENTS AND FUNCTION<\/p>\r\n Butcher’s Broom 50:1 Extract<\/p>\r\n Butcher’s Broom is a herb also known as Ruscus aculeatus. It gets its name from the practice of butchers using it for its supposed antibacterial properties to clean their cutting boards. It has been used in traditional medicine for its vasoconstrictive and anti-inflammatory actions (reducing swelling, preventing hemorrhoids, etc.).<\/p>\r\n The plant contains a variety of saponins, which have been shown to activate alpha-1 adrenergic receptors and stimulate the release of norepinephrine. It also has a protective effect on capillaries, strengthens blood vessels, and helps maintain healthy circulation.<\/p>\r\n As discussed previously, this alpha-1 activation is important and has been shown to shift preadipocytes to beige cells as opposed to white adipose tissue. As well, recent research shows that when hibernating, animals’ thermosensitive mechanisms will detect ambient and body temperatures and, if falling under threshold, the SNS will release norepinephrine to activate BAT in order to maintain viable body temperatures.<\/p>\r\n Gypenosides (75%)<\/p>\r\n Gypenosides are saponins found in the jiaogulan plant. This ingredient targets both WAT and BAT. With it we get WAT browning and an increase in fat oxidation genes in both WAT and BAT. Obesogenic diet mice treated with Gypenosides had a significantly reduced bodyweight vs. control, with lower cholesterol and insulin resistance. Gypenosides potently activate AMPk, which is tied directly to the cGMP\/cAMP systems and sympathetic\/parasympathetic nervous systems (metabolic autopilots), and amplify the lipolytic\/thermogenic effects on brite cells.<\/p>\r\n Menthol Crystals<\/p>\r\n Aside from B3 adrenergic receptor activation, the other most important way to start the browning process of WAT browning, as previously discussed, is through cold exposure. By exposing the body to cold temperatures long-term, it activates the TRPM8 receptor, which triggers browning in order to more effectively use WAT to create body warmth.<\/p>\r\n TRPM8 activation also enhances the thermogenic function of brown adipocytes through UCP1 and the b-adrenergic pathway.<\/p>\r\n So Menthol mimics long-term cold exposure by activating the TRPM8 channel, which has been shown to induce WAT browning as well as an upregulation in BAT thermogenesis. This has been shown to increase core temperature, reduce body fat and improve glucose metabolism.<\/p>\r\n Vanillin<\/p>\r\n An ingredient used in fake vanilla extracts for baking, Vanillin (and its metabolite Vanillic Acid) are metabolic derivatives from Anthocyanins. In addition to favorably reducing the ratio of Firmicutes to Bacteroides, resulting in a favorable gut environment for fat loss, Vanillin potently induces both browning of white fat and expression of UCP1.<\/p>\r\n Vanillin also increases glucose uptake in muscle tissue as well as regulating redox imbalances and inflammation.<\/p>\r\n Black Pepper Extract (20% Piperine)<\/p>\r\n TRPV1 is a capsaicin and vanilloid receptor in the body that is responsible for detection and regulation of body temperature and pain. More recently this receptor has been identified as a major player in obesity and body fat regulation. Stimulation of TRPV1 has been shown to upregulate BAT and increase fat oxidation and energy expenditure. TRPA1 is a similar receptor that functions to recognize cold and pain. Piperine, as well as several other compounds in black pepper, have been shown to be TRPV1 and TRPA1 agonists, with an even greater efficacy than capsaicin.<\/p>\r\n Trans-Cinnamaldehyde<\/p>\r\n Trans-Cinnamaldehyde is a pungent compound from cinnamon or dried cassia bark. It has been shown to increase UCP1 in both WAT and BAT, inducing browning of WAT cells. It also activates the cold receptor TRPA1. Back to those rodents fed obesogenic diets, Trans-Cinnamaldehyde inhibited hypertrophy of adipose cells, decreased body fat (including visceral fat), decreased voluntary food intake, and improved insulin sensitivity.<\/p>\r\n Salvia Miltiorrhiza 20:1 (Ethanol Extract)<\/p>\r\n Salvia Miltiorrhiza is a fascinating plant containing potent compounds that inhibit an enzyme called DGAT (diacylglycerol acyltransferase). Salvia Miltiorrhiza is able to prevent the final step in esterifying lipids into the form that WAT need them in – namely triacylglycerides (triglycerides). This keeps the lipids circulating in the bloodstream to be picked up and used by peroxisomes and mitochondria, and thrown off as heat.<\/p>\r\n Salvia Miltiorrhiza also inhibits SMAD2\/3 expression (see the BMP writeup), which suppresses myostatin activity and preserves muscle mass.<\/p>\r\n Salvia Miltiorrhiza has a dramatic effect on mitochondrial function in brite cells, basically turbocharging their activity by amplifying UCP1 activity.<\/p>\r\n Rutaecarpine<\/p>\r\n Contained in large quantities in the evodia fruit, it was first thought the Evodiamine was the compound responsible for the increase in non-shivering thermogenesis. Evodiamine turned out to be a huge disappointment, because it turns out the Rutaecarpine was what we were looking for.<\/p>\r\n Potently activating both AMPk and PGC-1a, Rutaecarpine also very strongly increases thermogenesis as well as mitochondrial biogenesis in brite cells. The more mitochondria, the more uncoupling and thus more thermogenesis and more fat burned.<\/p>\r\n Rutaecarpine also inhibits adipogenesis and lipogenesis, preventing lipid accumulation in WAT. Remember lipids in WAT have to be removed through a process of lipolysis before they can be transferred to metabolically active tissue and organelles (peroxisomes, mitochondria). By preventing WAT from accumulating lipids as well as crippling the body’s ability to simply make more white fat cells, all while shutting the lipids into the metabolically active brown\/brite fat cells, the process of thermogenesis becomes more efficient.<\/p>\r\n Sesamol<\/p>\r\n Sesamol is a phenol derivative of sesame oil with antioxidant and anti-inflammatory properties. This is another ingredient in the formula with the aforementioned two-pronged attack. It downregulates adipogenic differentiation factors (C\/EBPa, PPARy, SREBP-1) and decreases fat accumulating enzymes like fatty acid synthase (FAS), while upregulating fat oxidizing enzymes like HSL, LPL and AMPk. In mice on an obesogenic diet, it decreased fat mass and adipocyte size in both WAT and BAT by increasing UCP1 and PCG-1a.<\/p>\r\n Borneol<\/p>\r\n Borneol is a very potent P-glycoprotein efflux pump inhibitor. While “distracting” the P-gp pump, the ingredients of BRITE are able to enter the body unhindered by this physiochemical saboteur. As an additional benefit, Borneol also activates the TRPM8 cold receptor.<\/p>\r\n Myricetin-Nicotinamide Crystalline Complex<\/p>\r\n The primary superstar of the new formula, Myricetin is an incredibly diverse and hugely potent ingredient.<\/p>\r\n Let’s do a quick functional run through.<\/p>\r\n GLP-1 agonist – GLP-1 agonists are all the rage for weight loss right now. GLP-1 stands for Glucagon-like Peptide 1. Initially targeted to reverse type 2 diabetes, GLP-1 agonists soon manifested an interesting secondary effect – massive and rapid fat loss. As research gains traction, several explanations are emerging. A potent appetite suppression pathway, GLP-1 appears to be extremely active in the brain, activating brain-specific AMPk (hypothalamus, etc.) and stimulating central activation of brown\/brite fat thermogenesis. They also are highly active in increasing muscle-specific glucose uptake, and are effective at improving cardiac function. GLP-1 agonists are inactivated by something called dipeptidyl peptidase-4 (DPP-4). Interestingly enough, Myricetin inhibits DPP-4, thus amplifying and prolonging its own effect.<\/p>\r\n Myricetin has also been shown to be incredibly potent at inducing brite cell conversion, activating non-shivering thermogenesis, and dramatically increasing mitochondrial biogenesis (formation of new mitochondria).<\/p>\r\n GSK3b – Touched on briefly in the TopMuscle writeup, Glycogen Synthase Kinase 3b functions to inhibit a ton of growth associated positive effects in the body. This includes muscle growth, glycogen formation, and most importantly, brown\/brite fat thermogenesis. In fact, its potency at shutting down non-shivering thermogenesis is stunning. As luck (or design) would have it, Myricetin is the most potent GSK3b inhibitor so far found in natural form, with an IC50 of 900 nanomoles – incredibly potent.<\/p>\r\n PDE3b – as mentioned elsewhere, in order for BAT\/BRITE thermogenesis to be maximized, both PDE3b and PDE4D need to be inhibited. As if Myricetin hasn’t already shown to be badass, it also inhibits PDE3b.<\/p>\r\n Myricetin sounds great – let’s toss that in. Well, being a flavonoid, Myricetin has one of the worst oral absorption profiles I’ve ever seen, at very low single digit %. Other absorption enhancing methods (cyclodextrin, etc.) also turned out to be disappointing. However, I worked out a crystallization process with Nicotinamide that yielded some absolutely gorgeous, and highly absorbable, crystals – enabling us to include this spectacular ingredient in the formula.<\/p>\r\n The best part? Nicotinamide is also a highly potent brown fat activating ingredient, by both amplifying adrenergic signaling at the B3 receptor and by triggering mitochondrial biogenesis, as well as increasing expression of PPARa and PGC-1a.<\/p>\r\n Fucoxanthin 40%<\/p>\r\n Fucoxanthin is a simple ingredient. It dramatically increases expression of UCP1, which should be clear by now.<\/p>\r\n Ginger-6 Specialized Extract (std for 6-Paradol, 6-Shogaol, 6-Gingerol)<\/p>\r\n Ginger is absolutely one of the most popular plants for digestion, soothing a dysfunctional stomach, and tossing back after sushi and wasabi. It is also popular for fat loss, though in previous usages sort of haphazardly tossed in. I’m sure you’ve also seen something called Grains of Paradise (6-Paradol) used in competing formulas, though with highly mixed, often disappointing results. Turns out, if you know the correct solvents to use and in what order, you can extract the 3 main “browning” compounds from Ginger in high concentrations.<\/p>\r\n 6-Paradol – As mentioned it has become a commonly used ingredient. Another compound used to increase WAT browning, 6-Paradol also increases expression of PCG-1a and UCP1, resulting in increased thermogenesis with measurable temperature increases in brite\/brown adipose. However, of the three it appears to be the weakest.<\/p>\r\n 6-Shogaol – The immediate precursor of 6-Paradol, 6-Shogaol shows extreme promise as a thermogenic and browning agent, both in mature and preadipocytes. Increasing expression of the usual suspects (PCG-1a, UCP1), 6-Shogaol also increases mitochondrial turnover and biogenesis, increases the binding energy of ligands in the essential B3 adrenoreceptors (amplified signaling), and provides for a dramatic upregulation of beige markers, indicating significant browning of WAT.<\/p>\r\n 6-Gingerol – Along with 6-Shogaol, the most dominant compound in ginger – and the most potent. Sharing functionality with 6-Shogaol (all pathways similarly, but more potently, activated), 6-Gingerol also inhibits lipogenesis. 6-Gingerol also shows an extremely potent ability to break the giant lipid droplet which characterizes WAT into smaller, multiple droplets – enabling the shift to classical brite characteristics more easily.<\/p>\r\n Humulus Japonicus Extract 50:1 (Water)<\/p>\r\n Humulus Japonicus Extract is a new and exciting addition to the formula. In addition to inducing browning of WAT, it exerts potent antioxidant effects and increases expression of both AMPk and UCP1, as well as being a decent PPAR-delta agonist. The difference in hibernating animals using more PPARa to provide mitochondrial substrate in the liver is that they generally spend the winter dormant, whereas humans have the added benefit of physical motion, thus adding PPAR-delta, which is dominant in skeletal muscle, to the mix.<\/p>\r\n Quercetin-Theobromine Crystalline Complex<\/p>\r\n An absolute thermonuclear addition to the new formula is an ingredient combination I’ve been trying to fit for years, and this is an incredibly fortuitous (that means lucky) addition. Though they are grown together into a crystalline complex, which mostly enhances absorption by several fold, we will take each ingredient separately.<\/p>\r\n Quercetin – The Big Q is an extremely common compound in most plants. In addition to acting as a potent zinc ionophore (escort molecule into the cells), it is quite the potent antioxidant. But let’s get to the good stuff…<\/p>\r\n A 2021 study showed Quercetin to do a whole host of things related to BAT\/brite activation. It increases expression of PGC-1a (necessary for brite conversion) and UCP1, reduces plasma cholesterol, increases expression of the elusive (in humans) B3 adrenoreceptor (which is a key in the whole package), and as well induces mitochondrial transcription factors. Best of all? It was also discovered to be a very potent PDE4D inhibitor (see the section on phosphodiesterases\/cAMP) and, less potently, a PDE3b inhibitor. Recall that both PDE3b inhibition and PDE4D inhibition are required for both browning and optimized non-shivering thermogenesis.<\/p>\r\n As a side note, Quercetin decreases Firmicutes (starts with F for Fatty) to Bacteroides ratio in the gut, thus leading to a leaner phenotype expression.<\/p>\r\n Now Quercetin, while relatively inexpensive, has horrible solubility in water and dismal oral absorption. The crystallization with Theobromine increases oral absorption substantially.<\/p>\r\n Theobromine – Starting where we left off with Quercetin, Theobromine is ALSO quite a potent PDE4D inhibitor, the combination pretty much providing everything we need to preserve SNS cAMP signaling and optimized thermogenesis. But wait...there’s more!<\/p>\r\n Theobromine is a major component of cocoa. It has been toyed with, mostly unsuccessfully, in fat burning formulas for decades. Knowing what we know now about mechanisms, it makes sense why it didn’t deliver as promised.<\/p>\r\n Theobromine increases non-shivering thermogenesis, increases expression of PGC-1a, UCP1, other brite specific markers (we won’t be delving into those here quite yet) as well as increasing transport molecules like CPT1, which escorts shortened fatty acids from peroxisomes into the mitochondria for further beta-oxidation (and in our case, uncoupling\/heat production rather than ATP yield). In addition, Theobromine activates both B3 adrenoreceptors and AMPk, with the end result being a backblast of thermogenesis. As well, Theobromine suppresses preadipocyte differentiation, lipogenesis, and extends the browning effect to sub-mature adipocytes.<\/p>\r\n Oleuropein 50%<\/p>\r\n Oleuropein, contained in the olive plant, appears to be one of the main compounds contributing to the healthiness of the Mediterranean Diet. A unique compound, Oleuropein both dramatically increases UCP1 expression, and increases adrenaline\/noradrenaline secretion (absolutely essential for any kind of lipolysis, and therefore thermogenesis). Adrenaline\/noradrenaline acts as a ligand at the B3 adrenoreceptor (which, if you have been following has had both quantity increased as well as binding increased and signal amplified), the end result being hyperactivation of non-shivering thermogenesis.<\/p>\r\n We mentioned BMP7 also being essential to brown\/brite thermogenesis. While we are using a 50% oleuropein extract here, the other polyphenols in Olive (the “other” 50%) have been demonstrated to increase expression of BMP7, thus completing the perfection of our formula.<\/p>\r\n CONCLUSION<\/p>\r\n As you can see, we have exhaustively targeted all of the known pathways of creating and activating brite cells in the body through either recruiting precursor cells or converting mature white cells. Regular supplementation should encourage fat loss and mimicking of a lean phenotype acutely, and even more so when taken chronically – as brite cells don’t immediately revert back to white adipose upon cessation of the product. BRITE is a long-term solution to an ongoing, serious problem plaguing modern society.<\/p>\r\n <\/p>\r\n Epitome is a brand new, cutting-edge development in fat loss. It works in ways we've only previously been able to fantasize about. Epitome helps control appetite and accelerates fat burning by manipulation of the leptin pathway. By increasing leptin sensitivity and keeping leptin levels within normal range, the brain and body self-adjust to drive your physique where it should be: Lean. Leptin signals will tell your body that it's not hungry while at the same time telling your brain to burn that fat!<\/span> Serving size: 2 caps<\/p>\r\n Per Serving:<\/p>\r\n Chitosan forms a mucoadhesive which will increase time in contact with the intestinal wall, also increasing absorption. *Magnolol - potent Magnolia compound which suppresses Cortisol induced visceral fat accumulation (belly fat), inhibits aromatase, as well as inhibiting PTP-1b (same as BA)<\/span><\/p>\r\n *Semen Cassiae - is an ingredient that boosts lipolytic function. Working with the rest of the formula, SC acclerates release of fatty acids from fat cells to be burned, as well as boosting fat burning pathways.<\/span><\/p>","gtin12":"780742996846","image":["https:\/\/siteimgs.com\/10017\/item\/epitome-rendering-300dpi_1694551512-0.jpg"],"brand":"EvoMuse","url":"https:\/\/www.dpsnutrition.net\/i\/17988\/evomuse-epitome-120-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"44.99","url":"https:\/\/www.dpsnutrition.net\/i\/17988\/evomuse-epitome-120-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"EvoMuse Eviscerate SMOLDER - 180 ml","sku":"EM002","description":" Eviscerate SMOLDER | A Kinder, Gentler Fat Loss Topical<\/strong><\/span><\/p>\r\n The king of fat loss topicals now has a milder cousin. Slightly reduced Capsaicin content makes it more bearable, while extra ingredients have been added to tighten up the skin. Eviscerate SMOLDER | A Kinder, Gentler Fat Loss Topical<\/strong><\/span><\/p>\r\n The king of fat loss topicals now has a milder cousin. Slightly reduced Capsaicin content makes it more bearable, while extra ingredients have been added to tighten up the skin. Gaspari finally answers the call for an effective fat burner that, not only incinerates body fat but also covers three other key areas to create the ultimate explosive fat burning and energy experience. First and foremost, I wanted to make a true thermogenic that had every proven ingredient to liberate and incinerate body fat. Then, to fuel your fat-burning workouts, my fat burner also had to give you smooth energy with natural stimulants. Not the edgy anxiety that makes you feel like you're crawling out of your skin. Next I wanted to make sure I added ingredients that help with mental focus to help you concentrate in the gym. And finally, because stimulants and thermogenics can increase cortisol (which is catabolic), I wanted to include proven ingredients that support the adrenal glands to help keep cortisol levels in check. New DTN8 accomplishes all that and more. With the most powerful array of synergistic fat burning and energy components available today, DTN8 is the ultimate fat destroyer you've been waiting for.<\/p> Disclaimer: Regular exercise and proper nutrition are essential components for achieving your fat loss goals.<\/p> \u2020THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.<\/p>","gtin12":"646511026537","image":["https:\/\/siteimgs.com\/10017\/item\/gaspari-dtn8-fat-burner_2677-0.jpg"],"brand":"Gaspari Nutrition","url":"https:\/\/www.dpsnutrition.net\/i\/29896\/gaspari-dtn8-fat-burner-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"29.99","url":"https:\/\/www.dpsnutrition.net\/i\/29896\/gaspari-dtn8-fat-burner-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Gaspari Nutrition DTN8 - 2 x 60 Capsule Bottles TWINPACK","sku":"GP2353","description":"Lipo Elite<\/h5>
Lipo Elite<\/h5>
Let\u2019s Examine the Ingredients:<\/h5>
Cocoabuterol\u00ae:<\/h5>
Thermogenic Effects:<\/h5>
Improved Insulin Sensitivity:<\/h5>
Lean Muscle Building & Sparing:<\/h5>
Stimulant Free Energy & Mood Booster:<\/h5>
CaloriBurn GP\u00ae:<\/h5>
GBB (as gbbBURN\u2122):<\/h5>
Caffeine Anhydrous:<\/h5>
DiCaffeine Malate (as Infinergy\u2122):<\/h5>
N-Dimethylphenethylamine:<\/h5>
Theobromine:<\/h5>
Synephrine:<\/h5>
KannaEase:<\/h5>
AstraGin\u00ae:<\/h5>
Bioperine\u00ae:<\/h5>
LipoVantage<\/h1>\r\n
Maximize Fat Burning<\/span><\/h2>\r\n
Support Appetite Control<\/span><\/h2>\r\n
Ultra-Potent 1000 mg. MitoBurn® Per Serving<\/span><\/h4>\r\n
LipoVantage Highlights\/Supports:<\/strong><\/span><\/h3>\r\n
Ask Yourself a Few Questions:<\/span><\/strong><\/h4>\r\n
Melt Away Stubborn Body-Fat <\/span><\/h4>\r\n
Support Appetite Control & Mimic the Effects of Exercise<\/span><\/h4>\r\n
Help Preserve Lean Muscle While Dieting<\/span><\/h4>\r\n
Who is LipoVantage for? <\/span><\/h3>\r\n
Ultra-Potent 1,000 Mg. MitoBurn® Per Serving<\/span><\/h4>\r\n
So, you want a fat burner that works in a lot of different ways?<\/span><\/h3>\r\n
LipoVantage<\/span><\/h4>\r\n
Multi-Phase Fat Loss Catalyst<\/span><\/h4>\r\n
What does the term PPAR mean and what are PPAR activators?<\/span><\/h3>\r\n
LipoVantage<\/span><\/h4>\r\n
Revolutionary Multi-Ingredient PPAR Activation Formula<\/span><\/h4>\r\n
Let’s Examine the Ingredients:<\/span><\/h3>\r\n
MitoBurn® (L-BAIBA):<\/span><\/h4>\r\n
Hops (standardized for Isohumulones):<\/span><\/h4>\r\n
Stearoylethanolamide (SEA):<\/span><\/h4>\r\n
Oleoylethanolamide (OEA):<\/span><\/h4>\r\n
CaloriBurn GP®:<\/span><\/h4>\r\n
AstraGin®:<\/span><\/h4>\r\n
Bioperine®:<\/span><\/h4>\r\n
<\/p>\r\n
Stacking & Synergy: <\/span><\/h3>\r\n
Ultra-Potent 1000 mg. MitoBurn\u00ae Per Serving<\/h5>
Ask Yourself a Few Questions:<\/h5>
Who is LipoVantage for?<\/h5>
So, you want a fat burner that works in a lot of different ways?<\/h5>
What does the term PPAR mean and what are PPAR activators?<\/h5>
Let\u2019s Examine the Ingredients:<\/h5>
MitoBurn\u00ae (L-BAIBA):<\/h6>
MitoBurn\u00ae (L-BAIBA) Highlights\/Supports:<\/h6>
MitoBurn\u00ae (L-BAIBA) as a PPAR Activator:<\/h6>
Hops (standardized for Isohumulones):<\/h6>
Stearoylethanolamide (SEA):<\/h6>
Oleoylethanolamide (OEA):<\/h6>
CaloriBurn GP\u00ae:<\/h6>
AstraGin\u00ae:<\/h6>
Bioperine\u00ae:<\/h6>
Stacking & Synergy:<\/h5>
Non-Stimulant Thermogenic and Recomposition Agent<\/h5>
<\/p>\r\n
<\/p>\r\n
Ingredients:<\/h5>
Magnolia-Cyclodextrin Complex<\/h5>
Euphorbia Kansui Triterpenoids<\/h5>
Momordica Charantia extract<\/h5>
Galangin<\/h5>
Ingredients:<\/h5>
Magnolia-Cyclodextrin Complex<\/h5>
Euphorbia Kansui Triterpenoids<\/h5>
Momordica Charantia extract<\/h5>
Galangin<\/h5>
<\/p>","gtin13":"0758381476494","image":["https:\/\/siteimgs.com\/10017\/item\/brite-rendering_1703084216-0.jpg"],"brand":"EvoMuse","url":"https:\/\/www.dpsnutrition.net\/i\/28735\/evomuse-brite-capsules-120-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"49.99","url":"https:\/\/www.dpsnutrition.net\/i\/28735\/evomuse-brite-capsules-120-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"EvoMuse Brite Capsules - 360 Capsule (2 x 180 Capsule Bottles) TWINPACK *New Formula","sku":"EM2036","description":"
<\/p>","gtin13":"0758381476494","image":["https:\/\/siteimgs.com\/10017\/item\/2brite_1703091174-0.jpg"],"brand":"EvoMuse","url":"https:\/\/www.dpsnutrition.net\/i\/33659\/evomuse-brite-capsules-120-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"87.99","url":"https:\/\/www.dpsnutrition.net\/i\/33659\/evomuse-brite-capsules-120-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"EvoMuse DCP Ultra - 180 Capsules","sku":"EM051","description":"
","image":["https:\/\/siteimgs.com\/10017\/item\/dcp_1655572491-0.jpg"],"brand":"EvoMuse","url":"https:\/\/www.dpsnutrition.net\/i\/32043\/evomuse-dcp-ultra-180-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"56.99","url":"https:\/\/www.dpsnutrition.net\/i\/32043\/evomuse-dcp-ultra-180-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"EvoMuse Epitome - 120 Capsules","sku":"EM023","description":"
The Epitome of Fat Loss<\/strong><\/span><\/h2>\r\n
With the addition of Gypenosides we boost AMPk signals, literally causing the body to react as if you are smack dab in the middle of a heavy demanding workout, causing additional acceleration of fat loss. Epitome is exactly what it promises — the epitome of fat loss.<\/span><\/p>\r\n
Epitome<\/strong>
Fat Loss Amplifier<\/strong>
120 Capsules<\/strong><\/p>\r\n\r\n Birch Bark Extract 20:1<\/td>\r\n 200mg<\/td>\r\n<\/tr>\r\n \r\n Orthosiphon Staminus Ethanol leaf Extract 20:1<\/td>\r\n 100mg<\/td>\r\n<\/tr>\r\n \r\n Gynostemma Pentaphyllum 98%<\/td>\r\n 125mg<\/td>\r\n<\/tr>\r\n \r\n Stem Bromelain (800,000 U\/g)<\/td>\r\n 300mg<\/td>\r\n<\/tr>\r\n \r\n Betulinic Acid\/Ascorbic Acid Crystalline Complex<\/td>\r\n 33mg<\/td>\r\n<\/tr>\r\n \r\n Magnolia Officianalis (60% Magnolol)<\/td>\r\n 150mg<\/td>\r\n<\/tr>\r\n \r\n semen cassiae 20:1 Hydroalcoholic<\/td>\r\n 200mg<\/td>\r\n<\/tr>\r\n \r\n CHitosan<\/td>\r\n 50mg<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n
Quick update<\/strong><\/span>
We have moved to a MUCH upgraded formula, while trying to keep the price close to the same. Upgrades are:
Betulinic Acid - The herbal extract will be blended with a Betulinic Acid \/ Ascorbic Acid cocrystal, which increases solubility and absorption over 20 fold. In addition, the<\/p>\r\n
Gypenosides are comparable to Queen Bee Acid as an AMPk activator, but at a much lower cost, offsetting the very expensive BA.
Stem Bromelain inhibits an enzyme called PDE3B. PDE3B is activated by insulin, and contributes to the blunting of lipolysis through elevated insulin levels. This means Epitome, in addition to all of the potent effects, will also not be affected as bad by food intake\/elevated insulin.<\/p>\r\n
SMOLDER™ will produce rapid fat loss around the abdominal region and, especially for women, in the hip\/butt\/thigh region.
Eviscerate SMOLDER<\/strong><\/span>
6 fl oz.<\/strong><\/span>
Water, Isopropyl Alcohol, Benzyl Alcohol, Cetearyl Isononanoate, Ceteareth-20, Cetearyl Alcohol, Glycerin, Ceteareth-12, Cetyl Palmitate, Triglyceride Complex, N-Methyl-2-Pyrrolidone, Raspberry Ketones, Yohimbine HCl, Theophylline, 18-B Glycyrrhetinic Acid, Caffeine Anhydrous, 50% Chlorogenic Acid Green Coffee Bean Extract, Aloe Extract, Bergenin, Ginger Extract, Cucumber Extract, Beta-Escin, Benzyl Nicotinate, Dandelion Extract, L-Carnitine, Ellagic Acid 98%, Banaba Leaf Extract, Hydroxyethyl Acrylate \/ Sodium Acryloyldimethyl Taurate Copolymer, L-Menthol, Capsaicin 98%.<\/span>
Directions: Apply 3-4 pumps over entire ab area or other stubborn areas.<\/span><\/p>","gtin12":"700112961359","image":["https:\/\/siteimgs.com\/10017\/item\/em002_1745597078-0.jpg"],"brand":"EvoMuse","url":"https:\/\/www.dpsnutrition.net\/i\/15644\/evomuse-eviscerate-smolder-5-oz.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"45.99","url":"https:\/\/www.dpsnutrition.net\/i\/15644\/evomuse-eviscerate-smolder-5-oz.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"EvoMuse Eviscerate SMOLDER - 2 x 180 ml TWINPACK","sku":"EM2002","description":"
SMOLDER™ will produce rapid fat loss around the abdominal region and, especially for women, in the hip\/butt\/thigh region.
Eviscerate SMOLDER<\/strong><\/span>
6 fl oz.<\/strong><\/span>
Water, Isopropyl Alcohol, Benzyl Alcohol, Cetearyl Isononanoate, Ceteareth-20, Cetearyl Alcohol, Glycerin, Ceteareth-12, Cetyl Palmitate, Triglyceride Complex, N-Methyl-2-Pyrrolidone, Raspberry Ketones, Yohimbine HCl, Theophylline, 18-B Glycyrrhetinic Acid, Caffeine Anhydrous, 50% Chlorogenic Acid Green Coffee Bean Extract, Aloe Extract, Bergenin, Ginger Extract, Cucumber Extract, Beta-Escin, Benzyl Nicotinate, Dandelion Extract, L-Carnitine, Ellagic Acid 98%, Banaba Leaf Extract, Hydroxyethyl Acrylate \/ Sodium Acryloyldimethyl Taurate Copolymer, L-Menthol, Capsaicin 98%.<\/span>
Directions: Apply 3-4 pumps over entire ab area or other stubborn areas.<\/span><\/p>","gtin12":"700112961359","image":["https:\/\/siteimgs.com\/10017\/item\/em2002_1745597066-0.jpg"],"brand":"EvoMuse","url":"https:\/\/www.dpsnutrition.net\/i\/35307\/evomuse-eviscerate-smolder-2-x-180-ml-twinpack.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"85.98","url":"https:\/\/www.dpsnutrition.net\/i\/35307\/evomuse-eviscerate-smolder-2-x-180-ml-twinpack.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"EvoMuse Exemplar","sku":"EM056","image":["https:\/\/siteimgs.com\/10017\/item\/bottle_1730409728-0.jpg"],"brand":"EvoMuse","url":"https:\/\/www.dpsnutrition.net\/i\/34648\/evomuse-exemplar.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"79.99","url":"https:\/\/www.dpsnutrition.net\/i\/34648\/evomuse-exemplar.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"Gaspari Nutrition DTN8 - 60 Capsules","sku":"GP353","description":"EXPLOSIVE FAT BURNER<\/h5>
EXPLOSIVE FAT BURNER<\/h5>