<\/p>\r\n
Mix one scoop of dozer with 8-10 oz of cold or warm water or preferred beverage 30-45 minutes prior to bed. This is going to make you start feeling tired. Do not operate machinery or drive a vehicle after consuming dozer. Do not take for more than 4 consecutive days to avoid tolerance build up.<\/p>\r\n
Warning: consult with a physician prior to use if you have a medical condition. Don’t use if pregnant or lactating. Keep out of reach of children. Keep container tightly closed in a cool, dry and dark place.
These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.<\/p>\r\n
<\/p>\r\n
<\/p>","gtin12":"750258225808","image":["https:\/\/siteimgs.com\/10017\/item\/dozer-600x_1610654546-0.jpg"],"brand":"Axe and Sledge","url":"https:\/\/www.dpsnutrition.net\/i\/30527\/axe-sledge-fyred-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"34.99","url":"https:\/\/www.dpsnutrition.net\/i\/30527\/axe-sledge-fyred-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Blackstone Labs Anesthetized Chocolate - 25 Servings","sku":"BLB154","description":"
ANESTHETIZED | NEED HELP FALLING ASLEEP?<\/SPAN><\/P> One of the most challenging parts of bodybuilding is getting a good night's sleep. It doesn\u2019t matter if you\u2019re in contest prep or off season bulking, there\u2019s always a reason to not want to go to bed. Either the restlessness kicks in and you don\u2019t fall asleep until 4am or you\u2019re up every 2 hours hitting the bathroom or you\u2019re just uncomfortable from night sweats \u2013 it\u2019s always something! And to make matters worse, those 6-8 hours of sleep are easily the most important hours of the day for growth and recovery. A real bodybuilder takes his sleep just as seriously as he does his training and nutrition.<\/SPAN><\/P> ANESTHETIZED | GET REM SLEEP<\/SPAN><\/P> Anesthetized is the ultimate pre-bedtime, pharmacist formulated sleep aid solution for those with occasional sleeplessness issues. Scientifically proven to improve the speed at which you fall asleep and the rate at which your body reaches R.E.M. \u2013 making it incredibly important we dream better and longer for optimal muscle gains.<\/SPAN><\/P> ANESTHETIZED | PRODUCT RECOMMENDATIONS<\/SPAN><\/P> ANESTHETIZED | NEED HELP FALLING ASLEEP?<\/SPAN><\/P> One of the most challenging parts of bodybuilding is getting a good night's sleep. It doesn\u2019t matter if you\u2019re in contest prep or off season bulking, there\u2019s always a reason to not want to go to bed. Either the restlessness kicks in and you don\u2019t fall asleep until 4am or you\u2019re up every 2 hours hitting the bathroom or you\u2019re just uncomfortable from night sweats \u2013 it\u2019s always something! And to make matters worse, those 6-8 hours of sleep are easily the most important hours of the day for growth and recovery. A real bodybuilder takes his sleep just as seriously as he does his training and nutrition.<\/SPAN><\/P> ANESTHETIZED | GET REM SLEEP<\/SPAN><\/P> Anesthetized is the ultimate pre-bedtime, pharmacist formulated sleep aid solution for those with occasional sleeplessness issues. Scientifically proven to improve the speed at which you fall asleep and the rate at which your body reaches R.E.M. \u2013 making it incredibly important we dream better and longer for optimal muscle gains.<\/SPAN><\/P> ANESTHETIZED | PRODUCT RECOMMENDATIONS<\/SPAN><\/P> SLEEP is an all-natural, multifaceted sleep product designed to promote sleepiness and restful sleep to ensure maximum recovery. Quality sleep is one of the most important and essential actions your body needs to function properly. It is estimated that up to 33% of all adults do not get enough quality sleep. SLEEP is specifically designed to help fight off restlessness via different mechanisms of action, including inducing sleep and staying asleep.<\/P> HOW DOES CHEMIX SLEEP WORK? MagnaSleep? is an extremely potent form of magnolia bark extract(MBE), standardized for 90% of two powerful active phenolic compounds: magnolol and honokiol. These two bioactives also act on your GABAA receptors to help reduce anxiety and prepare your body for sleep. MBE has been used for thousands of years in Chinese and Japanese tradition medicine for help promote sleep and reduce anxiety. Magnolol and Honokiol both have very high binding affinity to your GABAA receptors, specifically interacting with the benzodiazepine binding site. This binding potentiates the sleep inducing-effect of baicalin. Since magnolol and honokiol can quickly be metabolized via glucuronidation, a hefty 25mg dose of BioPerine?(black pepper extract) was added to inhibit this process.<\/P> Cussonia zimmermannii is an African herb that has been studied for bioactive constituents that modulate your GABA receptors to induce sleep. The rootbark extract of C. zimmermannii has some very unique compounds known as polyacetylenes that have an extremely high affinity to GABAA receptors. These compounds have been shown to promote restfulness sleep, as well as staying asleep longer.<\/P> Hesperidin is one of the main bioactive compounds from citrus peel extract. It is a polyphenolic compound that has been shown to induce sleep, but does not act on the GABA receptor or benzodiazepine binding site. Studies show hesperidin interacts with your extracellular signal-regulated kinases 1\/2(ERK1\/2), located in the cortex and cerebellum. Hesperidin inhibits the activity of ERK1\/2, which may be linked to sedation. Studies show that hesperidin can induce sleepiness and enhance sleep, and may potentiate other sleep-promoting compounds that activate your GABAA receptors.<\/P> Apigenin is a polyphenolic flavonoid that is one of the most abundant and well-studied. Apigenin\u2019s mechanism of action is not directly on the GABA-benzodiazepine receptor, but does modulate its\u2019 activity. Studies show it has a synergistic effect when combined with GABAA agonists, like baicalin, magnolol and honokiol. It has been shown to reduce locomotor activity, which prevents restlessness and may help induce sleep. One study showed subjects taking apigenin slept for longer durations vs the placebo. Apigenin is also subject to glucuronidation, so absorption is critical. With 25mg of BioPerine? added to prevent this metabolism, you can be sure that the large dose of apigenin will be absorbed and utilized.<\/P> I formulated SLEEP because I have had sleeping issues all of my adult life. I have tried countless over-the-counter sleeping aids, melatonin, as well as 11 different pharmaceuticals. This combination of ingredients at clinical doses has dramatically improved my ability to fall asleep, my biggest issue, as well as stay asleep, my 2nd biggest issue. I scoured papers to look for natural sleep-enhancing compounds and I truly believe this formula will help anyone looking to get more restful sleep to help fully recover not only from exercise but from mental stress, as well.<\/P> References: <\/P> Core ZZZ is a perfectly-designed product with a single goal in mind: maximizing your recovery. We have included only the best and most effective recovery agents, at the proper serving sizes, to take the guesswork out of a good night\u2019s rest.<\/P> You\u2019re only as good as you can recover. And sleep is the most critical mechanism in your body\u2019s restorative process. Training hard, living hard and under the many stresses of life in 2020, a good night\u2019s sleep can make or break you. For that reason, we delivered DREAM to GCode Nation right on time. <\/SPAN><\/P> Critical vitamins and minerals, proven amino acid substrates, cutting edge compounds and old world holistic herbs combine to create an effective and healthy sleep support formula. Free of melatonin or harsh pharmaceuticals, GCode DREAM leaves you with no grogginess or hangover and is non-habit forming. DREAM will help you bounce back day after day on the grind, feeling better than ever, hungry for more. Relax. Rest. Restore. Recuperate. Recover. Dare to dream big. With DREAM. Only from GCode Nutrition. <\/SPAN><\/P> Restorative Recovery Complex L-Arginine AKG and L-Ornithine AKG two old school, proven amino acids in their most effective forms who simultaneously work to raise serum blood growth hormone levels at rest, also accelerating recovery rates over night. GABA in conjunction with Arginine AKG and Ornithine AKG, and their pro-GH properties can positively impact muscle mass, strength, metabolism and body composition.<\/SPAN><\/P> L-Theanine promotes relaxation, improving mood and relieving anxiety while also having antioxidant properties. It is also touted as a \"smart amino\u201d for its ability to heighten cognitive function.<\/SPAN><\/P> DIM, diindolymethane a novel and unique inclusion in this DREAM complex is the dynamic natural wonder compound. Found in cruciferous vegetables like cabbage, Brussels sprouts and broccoli, DIM works as an aromatase-inhibitor and hormone modulator benefiting both male and female athletes, preventing the conversion of testosterone to estrogen and encouraging the conversion of bad estrogen to good estrogen metabolites. On top of all that, DIM also has been show in studies to potentially work in helping combat common cancers.<\/SPAN><\/P> REM & Relaxation Complex <\/SPAN> <\/P> DREAM BIG. Every serving of DREAM delivers\u2026<\/SPAN><\/P> Glaxon Sedative Can: Enhance Sleep Quality Promote Relaxation Support Calmness Boost Recovery Improve Brain Health and Cognition Release Growth Hormone Decrease Stress Levels Elevate Mood Get the Restful Sleep Your Body Needs – Without Having to Count Sheep...<\/p>\r\n Enhance Sleep Quality It’s the end of a long day, and all you want to do is sleep, but you can’t seem to bring down your stress levels enough to relax and close your eyes. There’s nothing more frustrating than lying in bed staring at the ceiling, getting more and more frustrated by the minute because you can’t fall asleep. Well, there’s finally some good news to help solve your sleeplessness issue, and it comes in the form of Glaxon Sedative – the perfect end of day formula.<\/p>\r\n Thanks to Glaxon Sedative, you can finally sleep peacefully under the stars with ease. No more tossing and turning only to hear your alarm clock go off as a reminder that you haven’t slept a wink.<\/p>\r\n The precise formula found in Glaxon Sedative has been carefully chosen to help enhance sleep quality, promote relaxation, support calmness, boost muscle recovery, improve brain health, and more. This particular formula was designed to support proper rest and recovery so you not only can wake up the next morning fully energized but also help support your muscle-building and weight-loss goals.<\/p>\r\n Glaxon Sedative is the best nightcap you’ll ever prepare for yourself. Best of all, it comes in two delicious flavors – Ice Melon and Grape Drank.<\/p>\r\n Who Can Benefit from This Powerful Nighttime Relaxation Formula?<\/p>\r\n With Glaxon Sedative, it’s quite simple… if you’re looking for a better way to relax, rest, and recover, this end of day supplement has you covered. It’s easy to mix, satisfying to drink, and can provide you with the proper rest and recovery your mind and body needs.<\/p>\r\n The effects of Glaxon Sedative can be felt fully within 90 minutes of consumption. Simply plan out when you need to be in bed, make yourself a delicious Sedative nightcap, and let the powerful formulation get to work. When it does, you may not even remember your head hitting the pillow.<\/p>\r\n The Perfect End-of-Day Product to Promote Rest, Relaxation, and Recovery<\/p>\r\n Anyone who says life isn’t stressful is only fooling themselves. All of the day’s stressors can take a toll on the mind and body, which can negatively affect your sleep quality. With Glaxon Sedative, we take what could be an everyday issue and provide you with an easy to drink solution.<\/p>\r\n While getting you to sleep is one of the major advantages of using Glaxon Sedative, things were taken a few steps further in the way of helping you maximize your recovery while you sleep as well. Sedative includes specific ingredients to help elicit the release of growth hormone while also supporting muscle recovery from intense workouts.<\/p>\r\n Glaxon Sedative is the ultimate nighttime formula to support quality sleep while also supporting your muscle-recovery efforts.<\/p>\r\n Here are some of the key ingredients that can help maximize your results and how they can benefit you.<\/p>\r\n Magnesium Gluconate – Helps decrease stress and supports calmness by maintaining healthy levels of GABA, which can also help improve sleep quality<\/p>\r\n L-Glycine – Antioxidant properties to protect the body from oxidative stress while also having a calming effect that can help you fall asleep faster and more easily<\/p>\r\n GABA – A powerful ingredient that can promote lean muscle growth, improve fat-burning, lower blood pressure, and helps the mind and body relax to aid in better sleep quality<\/p>\r\n Magnolia Extract – Supports calmness, aids in reducing stress, and can help you fall asleep faster<\/p>\r\n Velvet Bean Extract – Can regulate mood and sleep cycles as well as the ability to improve brain function and well-being<\/p>\r\n L-Theanine – May improve the body’s ability to relax and remain calm in addition to supporting an improvement in sleep quality<\/p>\r\n Cholinace™ – A patented blend of choline sources that helps with cognition while also supporting REM sleep cycles<\/p>\r\n 5-HTP – Known as a “happy” ingredient, 5-HTP can improve mood, promote quality sleep, and can even aid in weight loss<\/p>\r\n Corydalis Yanhusuo – Can improve mood and sense of well-being while also helping you to fall asleep more easily<\/p>\r\n Phycocyanin – Contains powerful antioxidants and anti-inflammatory properties while being able to improve muscle strength and endurance<\/p>\r\n Astragin™ – A 100% natural and patented compound that helps increase the absorption of ingredients to allow for maximum results while also promoting gut health<\/p>\r\n Melatonin – Helps regulate your body’s circadian rhythm, which allows you to get a better night’s sleep, aids in managing cortisol levels, and may increase HGH levels<\/p>\r\n Toothed Clubmoss – Promotes cognition and brain health while also helping to protect the nerves<\/p>\r\n Ever feel like your pre-workout is lasting a little too long from your evening workout? Maybe if you had something to take the edge off, you could actually get to sleep on time. This is where Sedative does the most work, by being designed to bring those energy levels back down so you can get the right amount of sleep you need to properly recover.<\/P> Sedative works mostly by providing the \"inhibitory\u201d (as opposed to excitatory) neurotransmitters Glycine, GABA, and somewhat Serotonin. Some of these amino acids and extracts have a \"secretagogue\u201d effect in that they can elicit the release of growth hormone from the pituitary. Additionally, Sedative provides other components like Theanine and Melatonin to reduce stress and promote sleep.<\/P> Simply dissolve \u00bd to 1 full scoop of Sedative into 16oz (500mL) into water and mix vigorously. Consume 90 minutes prior to desired effect or before bedtime. To assess tolerance, start with \u00bd scoop, and if well-tolerated, up to 1 scoop can be taken every 24 hours.<\/P> <\/P> Methods Behind the Madness: Sedative by Glaxon<\/P> When trying to get a restful night\u2019s sleep, what is it that you\u2019re really missing that keeps you from dozing off? Did you take your pre-workout too late in the day? Do the stressors of daily life have a million thoughts running through your head in anticipation of tomorrow? Sedative is Glaxon\u2019s \"End of Day\u201d formula that is designed to soothe, relax, and de-stress the body so it can recover the best way it knows how - sleeping.<\/P> Amino acids as Neurotransmitter & Neurohormone Modulators<\/P> Initially we sought out the main inhibitory amino acids that can act as neurotransmitters to help promote relaxation and a calm state of being. This begins with two specific inhibitory amino acid neurotransmitters: L-Glycine and GABA (Gamma-Aminobutyric Acid). L-Glycine is actually the simplest of all amino acids, it\u2019s sweet tasting and only has a single hydrogen atom in its side chain. The main functions of Glycine occur in the retina, spinal cord, and brainstem where Glycine activates its receptor - causing a subsequent influx of chloride into neurons - and this causes what is known as \"inhibitory postsynaptic potential\u201d making neurons slow down and less likely to fire. There have been several studies that have analyzed L-Glycine supplementation in humans and have shown statistically significant improvements in \"feelings of fatigue\u201d1, increases in Glycine concentrations in the Central Nervous System2, and decreasing daytime sleepiness with improvements in performance of memory recognition tasks3. <\/P> However, L-Glycine isn\u2019t the main inhibitory neurotransmitter in the body - that role belongs to Gamma-Aminobutyric Acid or GABA. GABA is the principal inhibitory (vs. excitatory) neurotransmitter and it is estimated that at least 20% of all brain neurons are \"GABAergic\u201d4. Like the L-Glycine receptor, the GABAA receptor regulates the flux of Chloride (Cl-) ions across neuronal membranes. Now, there are several different subtypes of GABA receptors - some of which control the flow of other ions such as Calcium or Potassium, which also regulate membrane potential. Interestingly, GABA has varied attractions to each of its own receptors with the highest binding affinity actually for GABAC, which also has the longest binding duration and effect of any of the other GABA receptor subtypes5. In most cases of GABA receptor activation, deeper slow-wave sleep is enhanced6. Due to the high affinity of GABA to GABAC receptors, this leaves more possibilities for co-activations of other forms to be taken in conjunction with GABA supplementation.<\/P> A potential GABA-synergy with another amino acid, L-Theanine was studied in 2019. This combination of GABA and L-Theanine showed statistically significant effects over controls, but also over either amino acid administered individually. There was significant increases in REM sleep, and non-REM sleep, sleep duration, and a significant decrease in sleep latency7. L-Theanine appears to be another interesting amino acid. Though it isn\u2019t part of the traditional 20 proteogenic amino acids, L-Theanine is most commonly obtained in the diet through supplementation or ingestion of white tea. L-Theanine is reported to cross the blood-brain barrier and influence the secretion and function of neurotransmitters in the CNS at approximately 30-minutes after oral administration8, and reaches peak concentration at 5-hours post-administration before its effects begin to diminish9. Perhaps what is most interesting about L-Theanine is the range of receptors that it is capable of modulating, since there\u2019s no endogenous receptor for L-Theanine itself. Because of this, L-Theanine acts on AMPA, Kainate, and NMDA receptors of the brain10. Since these receptor types are most commonly stimulated by glutamate (an excitatory amino acid neurotransmitter) they\u2019re most prone to excitatory responses. L-Theanine actually has an antagonistic relationship with these receptors, this results in inhibition instead of excitation - and this decreases perceptual stress levels11. Additionally, L-Theanine has been studied for its effects on anxiety in comparison to alprazolam (Xanax). What was interesting about this study is that the comparative drug, alprazolam, had no anxiety dampening effects at rest or when faced with an anticipatory anxiety (inevitable electric shock) however, L-Theanine did have more significant relaxing effects under resting conditions12.<\/P> Another key amino acid found in Sedative is L-DOPA from extracted Mucuna pruriens or Velvet Bean. What\u2019s interesting about this amino acid is that it does cross the blood brain barrier and is the most common precursor to the neurotransmitter, dopamine. Coincidentally, Sedative also contains the amino acid precursor to serotonin in the form of 5-Hydroxytryptophan. However, once L-DOPA is converted into dopamine - this can also yield substantial amounts of adrenaline and norepinephrine as well. L-DOPA happens to also have another peculiar mechanism that hasn\u2019t been fully elucidated - the subsequent release of Growth Hormone-Releasing Hormone from the hypothalamus13. Though many studies have tried uncovering this mechanism behind L-DOPA\u2019s stimulative effect of growth hormone levels, perhaps the one that is most plausible is that L-DOPA provides precursors to dopamine, which in turn can become norepinephrine and stimulate alpha-adrenoreceptors - which could then stimulate a release of growth hormone14. <\/P> <\/P> Botanicals that Sedate<\/P> Next in Sedative are an interesting pair of herbal extracts that help further magnify the effects of this \"end of day\u201d formula. The common Magnolia tree (Magnolia officinalis) contains two compounds worthy of note: Magnolol & Honokiol. These two compounds are actually isomers of one another, but are commonly referred to collectively. Magnolol and honokiol can cross the blood-brain barrier15, can act as muscle relaxants16, and can diminish the release of histamine17 & leukotrienes18. Needless to say that all of these features are desirable for a relaxation formula, but Mangolol and Honokiol form some other helpful synergies in Sedative. First, it has an additive effect with L-Theanine being an antagonist of NMDA and metabotropic Glutamate receptors that have an inhibitory effect on the CNS19. Secondly, it has another potential additive effect when co-administered with GABA - where GABA predominates the GABAC receptors, while Magnolol & Honokiol occupy GABAA receptors20.<\/P> The second herbal extract that is most prominent in Sedative comes from Corydalis yanhusuo which is extracted for L-Tetrahydropalmitine (L-THP), which has been shown to have some anxiolytic (anxiety-reducing) activity21. It is interesting though, in how L-THP executes this task. Though it was previously thought that L-THP modulated GABA receptors, similarly to Magnolol & Honokiol, a study published in 2019 unveiled a different mechanism. It is through interactions with dopamine receptors that the \"hypnotic\u201d quality of L-THP is accomplished, but through mixed types of activity. The hypnotic effect of L-THP is through agonism (or promotion) of Dopamine-1 receptors - combined with antagonism (or diminished activation) of Dopamine-2 receptors22.<\/P> <\/P> A Crucial Mineral & The Hormone of Darkness<\/P> It has been proposed that subclinical magnesium deficiency can exacerbate conditions that result in chronic inflammatory stress23. Some studies have suggested a relationship between blood magnesium and the amount of sleep, with an increased slow-wave sleep (deep sleep) and decrease paradoxical sleep (REM sleep) when serum magnesium is high24. Not only does magnesium deficiency alter sleep and inflammatory status, but can also result in cognitive defects during waking hours. A potential mechanism that has been suggested highlight magnesium\u2019s role as being an NMDA receptor antagonist and GABA receptor agonist, thus resulting in decreased excitation of neurons25,26. Several other studies have also asserted that higher brain and blood magnesium levels are associated with a more consolidated and less fragmented sleep in both human and animal models, confirming that magnesium plays a role in modulating sleep quality27,28. <\/P> In the duality of day vs. night, there are two hormones that that claim dominion over these portions of our experience. The day is marked by exposure to the sun, and thus facilitates the conversion of cholesterol into Vitamin D (Cholecalciferol) which plays a vital role in calcium metabolism and bone integrity. However, when the sun goes down and our eyes no longer perceive light, Melatonin - the hormone of darkness takes over. The retina itself, gets triggered by a lack of photons from the surrounding environment, which sends a signal to what\u2019s called the suprachiasmatic nucleus, which then transmits a signal for the pineal gland to start its daily dump of melatonin into the central nervous system. Melatonin\u2019s synthesis and release are stimulated by darkness and inhibited by light. Typically, melatonin secretion increases soon after the onset of darkness, peaks in the middle of the night (2-4 AM), and then gradually falls during the second half of the night29. However, even the administration of melatonin from an exogenous (outside the body) source affects sleep propensity (how fast you fall asleep), as well as the duration and quality of sleep, and has hypnotic effects30. In summary, there\u2019s evidence to support the fact that melatonin has a hypnotic effect in humans. It\u2019s peak serum concentrations coincide with sleep. Its administration in doses that raise the serum concentrations to levels that normally occur nocturnally can promote and sustain sleep. Higher doses also promote sleep, possibly by causing relative hypothermia. Exogenous melatonin can also influence circadian rhythms, thereby altering the timing of fatigue and sleep29.<\/P> <\/P> Acetylcholine, Consciousness, and Dreaming<\/P> Acetylcholine actually has many jobs inside the body. During waking hours, its primary responsibility is being the neurotransmitter of neuro-muscular control (ie. the mind-muscle connection) and is essential for controlling selective attention. There are also many other theories as to the role of Acetylcholine that include the possibility that it affects discriminatory processes; increases signal-noise ratios; modulate the efficiency of cortical processing of sensory information; controls the reception and evaluation of stimuli for their level of significance; modifies cortical responsiveness in terms of the relevance and novelty; and confines the contents of the conscious stream31. <\/P> An interesting, nocturnal, responsibility of Acetylcholine is correlated with dreaming and subconscious memory consolidation. One of the most important neurophysiological events that triggers REM sleep and\/or dreaming is the firing of cholinergic neurons and to compound this, administration of an Acetylcholinesterase inhibitor (such as Huperzine A or Galantamine) actually decreases REM-sleep latency (how fast your start dreaming) and increases REM-sleep duration (how long your dreams are). It is also true that Acetylcholine levels are highest during waking and while dreaming, yet are significantly lower during non-dreaming sleep. It is also strikingly coincidental, that the discovery of Acetylcholine by Otto Loewi was the result of a dream.<\/P> However, there are cases where REM-sleep can occur without dreaming and that dreams can also occur without REM-sleep which lead to the conclusion that dopamine may play a significant role in the actual dream-state itself. In fact, if you consider that ~75% of total sleep time is actually non-REM sleep, it would imply that roughly 25% of REM-like dreams actually occur outside of normal REM sleep.<\/P> Another perplexing thing about dreams is that neural activity is not reactivated exactly in its original form. Waking firing sequences are reactivated in intermittent bursts, on a faster timescale than the original experience35. And rarely is a waking firing sequence reiterated exactly - although reactivated sequences statistically resemble waking activity, the \"replay\u201d is not always precise or in its original form, but instead remixes fragments of recent experiences with other content in a sense-making effort to reconcile new information with previously acquired information36. In support of the dreaming-memory hypothesis, we may have to realize that dreams may reflect an adaptive process of memory consolidation by which new learning is stabilized and integrated with our existing knowledge37. <\/P> <\/P> With Sedative, we\u2019ve sought to amplify the body\u2019s natural winding-down processes. As part of the body\u2019s natural circadian rhythms, we\u2019ve helped nurture these nocturnal events. Sedative supplies a range of inhibitory neurotransmitters combined with botanicals that synergistically amplify the effects these amino acid compounds by coactivating their receptors. Additionally, we supply natural growth hormone secretagogues to help facilitate recovery. Melatonin also provides an additional hypnotic effect while helping synchronize the circadian rhythm. Then finally through our inclusion of CholiaceTM and Huperzine A, we harness the subconscious effects of dreaming to help further facilitate memory consolidation and recall. All of these functions are accomplished while promoting quality sleep without the undesirable effects daytime grogginess the following day.<\/P> TRANQUILITY - NEW<\/p>\r\n Tranquility is an “End of Day” formula designed to help you unwind...<\/p>\r\n FAQS<\/p>\r\n WHY WOULD I TAKE IT? HOW DOES THIS WORK? HOW MUCH SHOULD I TAKE? TOP 5 STUDIES: TRANQUILITY - NEW<\/p>\r\n Tranquility is an “End of Day” formula designed to help you unwind...<\/p>\r\n FAQS<\/p>\r\n WHY WOULD I TAKE IT? HOW DOES THIS WORK? HOW MUCH SHOULD I TAKE? TOP 5 STUDIES: TRANQUILITY - NEW<\/p>\r\n Tranquility is an “End of Day” formula designed to help you unwind...<\/p>\r\n FAQS<\/p>\r\n WHY WOULD I TAKE IT? HOW DOES THIS WORK? HOW MUCH SHOULD I TAKE? TOP 5 STUDIES: One of the primary hormones produced in our brain that allows for quality sleep is Melatonin and is located in the pineal gland. This pineal is found in the epithalamus, near the center of the brain, between the two hemispheres. Melatonin helps control your daily sleep and wake cycles and regulates your \"internal clock\u201d known as your circadian rhythm. As the sun begins to set our body recognizes this and begins to adjust melatonin levels accordingly. Melatonin and other sleep and growth factors rise through the early evening and maintain levels appropriate for sleep overnight. As the sun begins to rise our body senses this and starts producing less and allowing us to wake refreshed the day before.<\/P> <\/P> Any number of factors both environmental and physiological can cause variations is melatonin release. Stress, anxiety, stimulants too late in the day, working overnights, external interruptions in normal sleep routines, hunger, depression\u2026 the list goes on and one. However, many people find that by supplementing with Melatonin, their sleep patterns can stabilize lowing them to fully recover from a challenging day\u2019s work, stressful day with the family or grueling training session in the gym. <\/P> The biggest issue with most people who take Melatonin and other sleep aids is the amount of ingested ingredients that are absorbed by the body. Often, the ingredients are broken down high in the GI system and are rendered useless by our digestion. Hi-Tech addresses this issue by utilizing a patented technology called Cyclosome\u2122 which allows the ingested Melatonin to travel further into the gut and to be much more readily absorbed. This allows for a more consistent level each night allowing the body to better self regulate its sleep patterns. <\/P> In addition, Hi-Tech's Melatonin takes the novel approach of a multi-stage delivery. The first stage is a rapid release of 3mg of Melatonin into the blood stream, allowing a peaceful entrance into the first stage of sleep. That is later followed by the release of 7mg which allows for a deeper sleep to be achieved. About the time that 7mg has been utilized by the body, the sun is rising and it\u2019s time to start the new day. A day began with the most restful night of sleep possible.<\/P> These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, cure, diagnose, or prevent any disease. This product should not be used in place of or as a substitute for recommendations by your healthcare professional.<\/P> SUGGESTED USE * Statements on this website have not been evaluated by the Food and Drug Administration. Products are not intended to diagnose, treat, cure, or prevent any disease.<\/P> <\/P><\/SPAN>","gtin12":"811836023756","image":["https:\/\/siteimgs.com\/10017\/item\/hi-tech-pharmaceuticals-m_2451-0.jpg"],"brand":"Hi Tech Pharmaceuticals","url":"https:\/\/www.dpsnutrition.net\/i\/29635\/hi-tech-pharmaceuticals-melatonin-10-mg-60-tab.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"11.98","url":"https:\/\/www.dpsnutrition.net\/i\/29635\/hi-tech-pharmaceuticals-melatonin-10-mg-60-tab.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Hi Tech Pharmaceuticals Somatomax Berry Banana - 20 Servings","sku":"HT074","description":" *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent disease. *Exercise and proper diet are necessary to maintain results. Results are not guaranteed and vary depending upon starting point, goals, and effort. <\/SPAN><\/P>\r\n <\/P><\/SPAN> <\/P>","gtin12":"811836020618","image":["https:\/\/siteimgs.com\/10017\/item\/somatomax-berry-banana-10_1605028212-0.jpg"],"brand":"Hi Tech Pharmaceuticals","url":"https:\/\/www.dpsnutrition.net\/i\/18499\/hi-tech-pharmaceuticals-somatomax-280-gram.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.95","url":"https:\/\/www.dpsnutrition.net\/i\/18499\/hi-tech-pharmaceuticals-somatomax-280-gram.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Hi Tech Pharmaceuticals Somatomax Exotic Fruit - 20 Servings","sku":"HT073","description":" *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent disease. *Exercise and proper diet are necessary to maintain results. Results are not guaranteed and vary depending upon starting point, goals, and effort. <\/SPAN><\/P>\r\n <\/P><\/SPAN> <\/P>","gtin12":"811836020625","image":["https:\/\/siteimgs.com\/10017\/item\/somatomax-exotic-fruit-10_1605028199-0.jpg"],"brand":"Hi Tech Pharmaceuticals","url":"https:\/\/www.dpsnutrition.net\/i\/18498\/hi-tech-pharmaceuticals-somatomax-280-gram.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.95","url":"https:\/\/www.dpsnutrition.net\/i\/18498\/hi-tech-pharmaceuticals-somatomax-280-gram.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Hi Tech Pharmaceuticals Somatomax Fruit Punch - 20 Servings","sku":"HT017","description":" *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent disease. *Exercise and proper diet are necessary to maintain results. Results are not guaranteed and vary depending upon starting point, goals, and effort. <\/SPAN><\/P>\r\n <\/P><\/SPAN> <\/P>","gtin12":"857084000231","image":["https:\/\/siteimgs.com\/10017\/item\/somatomax-exotic-fruit-10_1605028275-0.jpg"],"brand":"Hi Tech Pharmaceuticals","url":"https:\/\/www.dpsnutrition.net\/i\/2490\/hi-tech-pharm-somatomax-280-gram.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.95","url":"https:\/\/www.dpsnutrition.net\/i\/2490\/hi-tech-pharm-somatomax-280-gram.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Hi Tech Pharmaceuticals Somatomax Lemon Drop - 20 Servings","sku":"HT075","description":" *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent disease. *Exercise and proper diet are necessary to maintain results. Results are not guaranteed and vary depending upon starting point, goals, and effort. <\/SPAN><\/P>\r\n <\/P><\/SPAN> <\/P>","gtin12":"811836020632","image":["https:\/\/siteimgs.com\/10017\/item\/somatomax-lemon-drop-1024_1605028224-0.jpg"],"brand":"Hi Tech Pharmaceuticals","url":"https:\/\/www.dpsnutrition.net\/i\/18500\/hi-tech-pharmaceuticals-somatomax-280-gram.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.95","url":"https:\/\/www.dpsnutrition.net\/i\/18500\/hi-tech-pharmaceuticals-somatomax-280-gram.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Hi Tech Pharmaceuticals Somatomax Rocket Pop - 20 Servings","sku":"HT103","description":" *These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent disease. *Exercise and proper diet are necessary to maintain results. Results are not guaranteed and vary depending upon starting point, goals, and effort. <\/SPAN><\/P>\r\n <\/P><\/SPAN> <\/P>","gtin12":"811836022827","image":["https:\/\/siteimgs.com\/10017\/item\/hi-tech-pharmaceuticals-s_1415-0.jpg"],"brand":"Hi Tech Pharmaceuticals","url":"https:\/\/www.dpsnutrition.net\/i\/27192\/hi-tech-pharmaceuticals-somatomax-rocket-pop-280.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.95","url":"https:\/\/www.dpsnutrition.net\/i\/27192\/hi-tech-pharmaceuticals-somatomax-rocket-pop-280.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Metabolic Nutrition RelaXitrol - 60 Cap","sku":"MB082","description":" Formulated using the most powerful ingredients nature has to offer, RelaXitrol is the natural solution to help reduce anxiety, promote relaxation, and improve REM sleep... helping restore natural sleep patterns. If you\u2019re ready to unwind, get a healthy night\u2019s rest and wake up feeling refreshed, RelaXitrol is your answer!*<\/P> FORMULATED USING ONLY SCIENTIFICALLY RESEARCHED AND PROVEN INGREDIENTS, RELAXITROL IS DESIGNED TO:<\/P> Improve REM Sleep FOR RELAXATION: During times of high stress and anxiety, take one (1) capsule of RelaXitrol®.<\/P> FOR SLEEP: Start by assessing your tolerance with two (2) capsules of RelaXitrol 30 minutes prior to sleep. For maximum effect, the recommended serving is three (3) capsules.<\/P> Melatonin is a potent free radical scavenger naturally produced in the pineal gland and present in high amounts in the gastrointestinal tract. It is involved in many of the body, brain and glandular biological functions including regulation of normal sleep\/wake cycles, regulation of the immune system and maintenance of a healthy gastrointestinal lining.*<\/SPAN><\/P> Supplement Facts<\/SPAN><\/P> Serving Size: 1 Veg Capsule Melatonin 10 mg * <\/SPAN><\/P> * Percent Daily Values are based on 2,000 calorie diet. Other Ingredients:<\/SPAN><\/P> Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.<\/SPAN><\/P> Caution: For adults only. May cause drowsiness. Do not operate a vehicle or heavy machinery following consumption of melatonin. Consult physician if pregnant\/nursing, taking medication (especially sedatives and anti-depressants), or have a medical condition (including depression, high blood pressure and epilepsy). Keep out of reach of children.<\/SPAN><\/P> Store in a cool, dry place after opening. Please Recycle.<\/SPAN><\/P> NOW® Extra Strength Melatonin 10 mg has twice the Melatonin as in our 5 mg product.<\/SPAN><\/P> Made in the USA<\/SPAN><\/P> *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.<\/SPAN><\/P>","gtin12":"733739035578","image":["https:\/\/siteimgs.com\/10017\/item\/now-foods-melatonin-10-mg_843-0.jpg"],"brand":"Now Foods","url":"https:\/\/www.dpsnutrition.net\/i\/16762\/now-melatonin-10-mg-100-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"9.99","url":"https:\/\/www.dpsnutrition.net\/i\/16762\/now-melatonin-10-mg-100-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Now Foods Melatonin 3 Mg - 180 Cap","sku":"NO079","description":"
<\/DIV><\/DIV>","gtin12":"696302495981","image":["https:\/\/siteimgs.com\/10017\/item\/anesthetizedchocolate_1604339149-0.jpg"],"brand":"Blackstone Labs","url":"https:\/\/www.dpsnutrition.net\/i\/30270\/blackstone-labs-anesthetized-pineapple-25-servings.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"44.99","url":"https:\/\/www.dpsnutrition.net\/i\/30270\/blackstone-labs-anesthetized-pineapple-25-servings.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Blackstone Labs Anesthetized Pineapple - 25 Servings","sku":"BLB12","description":"
<\/DIV><\/DIV>","gtin12":"642125502580","image":["https:\/\/siteimgs.com\/10017\/item\/anesthetized-pineapple_1604340116-0.jpg"],"brand":"Blackstone Labs","url":"https:\/\/www.dpsnutrition.net\/i\/25415\/blackstone-labs-anesthetized-pineapple-25-servings.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"44.99","url":"https:\/\/www.dpsnutrition.net\/i\/25415\/blackstone-labs-anesthetized-pineapple-25-servings.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Chemix Sleep - 90 Cap","sku":"CMX19","description":"
<\/DIV>
Provides Incredible Rest
Aids With REM Sleep
No Hangover Effect
Boosts Overall Energy
Creates Better Daily Mood<\/P>
Assist Your Recovery And Induce Restfulness With The All New Chemix Ultra Premium Sleep Aid. The Guerrilla Chemist Has Gone Back To The Lab And Formulated Our First Ever Ultra Premium Sleep Aid Product. This One Of A Kind Formulation Will Turn Your Lights Out When It's Time To Get Your Rest. Chemix Sleep Will Provide The Best In Rest And Recovery With No Excess Hangover Leaving You Ready To Take On The Day With Plenty Of Energy And Focus.<\/P>
GABAiclin? is a trademarked extract of Scutellaria baicalensis, standardized for 30% of the main active baicalin. Baicalin is a positive allosteric agonist for your GABAA receptors. ?-aminobutyric acid, aka GABA is your main inhibitory neurotransmitter that essentially tells your brain it\u2019s time to get ready for sleep. Once baicalin binds to your GABAA receptor, it activates the receptor and elicits sedative, hypnotic, muscle relaxant and anxiolytic(anti-anxiety) properties. This is the same mechanism and receptor that a class of sleep medications known as benzodiazepines interacts with. Baicalin has been shown to increase slow-wave sleep(deep sleep), as well as REM(rapid eye movement) sleep. REM sleep is extremely valuable to your body, as it releases growth hormone(GH) to help aid in recovery.<\/P><\/DIV>
1. Chang HH, Yi PL, Cheng CH, et al. Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation. J Ethnopharmacol. 2011;135(2):359-368.
2. Shi, Yuan, et al. \"Herbal insomnia medications that target GABAergic systems: a review of the psychopharmacological evidence.\" Current Neuropharmacology 12.3 (2014): 289-302.
3. Ai, Jinglu, Xiaomei Wang, and Mogens Nielsen. \"Honokiol and magnolol selectively interact with GABAA receptor subtypes in vitro.\" Pharmacology 63.1 (2001): 34-41.
4. Squires, Richard F., et al. \"Honokiol and magnolol increase the number of [3 H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites.\" Neurochemical research 24.12 (1999): 1593-1602.
5. Chen, Chang-Rui, et al. \"Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, induces sleep via the benzodiazepine site of GABAA receptor in mice.\" Neuropharmacology 63.6 (2012): 1191-1199.
6. Senn, Martin W. Structures and evaluation of biologically active constituents of\" Cussonia Zimmermannii\" harms. Diss. University_of_Basel, 2006.
7. Mart\u00ednez, M. Cecilia, et al. \"Hesperidin, a flavonoid glycoside with sedative effect, decreases brain pERK1\/2 levels in mice.\" Pharmacology Biochemistry and Behavior 92.2 (2009): 291-296.
8. Fern\u00e1ndez, Sebasti\u00e1n P., et al. \"Synergistic interaction between hesperidin, a natural flavonoid, and diazepam.\" European journal of pharmacology 512.2-3 (2005): 189-198.
9. Fern\u00e1ndez, Sebasti\u00e1n, et al. \"Sedative and sleep-enhancing properties of linarin, a flavonoid-isolated from Valeriana officinalis.\" Pharmacology Biochemistry and Behavior 77.2 (2004): 399-404.
10. Salehi, Bahare, et al. \"The therapeutic potential of apigenin.\" International journal of molecular sciences 20.6 (2019): 1305.
11. Kim, Jae-Wook, et al. \"Enhancement of pentobarbital-induced sleep by apigenin through chloride ion channel activation.\" Archives of pharmacal research 35.2 (2012): 367-373.
Gazola, Andressa C., et al. \"Involvement of GABAergic pathway in the sedative activity of apigenin, the main flavonoid from Passiflora quadrangularis pericarp.\" Revista Brasileira de Farmacognosia 25.2 (2015): 158-163<\/P>
Put recovery at the top of your list by putting Core ZZZ at the center of your supplement lineup.<\/DIV><\/DIV>","gtin12":"672975009748","image":["https:\/\/siteimgs.com\/10017\/item\/core-zzz-1800x1800_1612041199-0.jpg"],"brand":"Core Nutritionals","url":"https:\/\/www.dpsnutrition.net\/i\/30073\/core-nutritionals-core-zzz-pineapple-peach-20.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.99","url":"https:\/\/www.dpsnutrition.net\/i\/30073\/core-nutritionals-core-zzz-pineapple-peach-20.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"G Code Nutrition Dream Natural Sleep Support - 120 Cap","sku":"GCN22","description":"
GABA (Gamma Aminobutyric Acid) is the body\u2019s chemical precursor to human growth hormone and is a central nervous system neurotransmitter that helps promote relaxation and a positive response to stress, this resulting tranquility translates to more restful sleep and a biomechanical inclination toward elevated endogenous growth hormone production.<\/SPAN><\/P>
As always, every GCode Nutrition supplement employs potent ingredients that harness the unparalleled power of Mother Nature. Inspired by many cups of late-night tea before bed, DREAM combines some of the most effective relaxation herbs on Earth into a single formula. Valerian, Chamomile and Lavender extracts together work to ease nerves and calm the overactive mind, facilitating deeper and more restful slumber. These centuries-old holistic herbal relaxation remedies are fully potentiated by BioPerine, the patented black pepper extract that ensures each of the DREAM components are properly utilized, reaching the bloodstream at their maximum efficacy.<\/SPAN><\/P>
GABA (Gamma Aminobutyric Acid)
Arginine AKG
Ornithine AKG (OKG)
L-Theanine
Diindolymethane (DIM)
Valerian
Chamomile
Lavender
BioPerine <\/SPAN><\/DIV><\/SPAN><\/DIV>","gtin12":"855816007282","image":["https:\/\/siteimgs.com\/10017\/item\/dream-front-d4ba503a-2532_1605282062-0.jpg"],"brand":"G Code Nutrition","url":"https:\/\/www.dpsnutrition.net\/i\/30086\/g-code-nutrition-dream-120-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.95","url":"https:\/\/www.dpsnutrition.net\/i\/30086\/g-code-nutrition-dream-120-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Glaxon Sedative End of Day Formula Ice Melon - 42 Servings","sku":"GN030","description":"
Glaxon Sedative Can:<\/p>\r\n
Promote Relaxation
Support Calmness
Boost Recovery
Improve Brain Health and Cognition
Release Growth Hormone
Decrease Stress Levels
Elevate Mood
Get the Restful Sleep Your Body Needs – Without Having to Count Sheep<\/p>\r\n
Ingredients in Sedative:<\/p>\r\n
Suggested Use:<\/p>\r\n
As a dietary supplement, mix ½ or 1 scoop into 16oz (~500mL) of water and mix vigorously. To assess tolerance, start with a ½ scoop, if well tolerated, up to 1 scoop may be taken every 24 hours. Consume 90 minutes before desired sleep time.<\/p>\r\n","gtin12":"850016284242","image":["https:\/\/siteimgs.com\/10017\/item\/sedative-icemelon_1605893792-0.jpg"],"brand":"Glaxon","url":"https:\/\/www.dpsnutrition.net\/i\/30374\/glaxon-sedative-end-of-day-formula-ice-melon-42.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.99","url":"https:\/\/www.dpsnutrition.net\/i\/30374\/glaxon-sedative-end-of-day-formula-ice-melon-42.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Glaxon Sedative Grape Drank - 42 Servings","sku":"GN018","description":"
<\/DIV>
WHY WOULD I TAKE IT?<\/P>
HOW DOES THIS WORK?<\/P>
HOW MUCH SHOULD I TAKE?<\/P>
Sedative, in summary:<\/P><\/P>
Inagawa K, Hiraoka T, Kohda T, Yamadera W, Takahashi M. Subjective effects of glycine ingestion before bedtime on sleep quality. Sleep Biol Rhythms. 2006;4(1):75-77.
Bannai M, Kawai N. New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep. Journal of pharmacological sciences. 2012;118(2):145-148.
Yamadera W, Inagawa K, Chiba S, Bannai M, Takahashi M, Nakayama K. Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes. Sleep Biol Rhythms. 2007;5(2):126-131.
Paredes RG, \u00c5gmo A. GABA and behavior: The role of receptor subtypes. Neuroscience & Biobehavioral Reviews. 1992;16(2):145-170.
Qian H, Dowling JE. Pharmacology of novel GABA receptors found on rod horizontal cells of the white perch retina. J Neurosci. 1994;14(7):4299-4307.
Gottesmann C. GABA mechanisms and sleep. Neuroscience. 2002;111(2):231-239.
Kim S, Jo K, Hong K-B, Han SH, Suh HJ. GABA and l-theanine mixture decreases sleep latency and improves NREM sleep. Pharmaceutical Biology. 2019;57(1):65-73.
TERASHIMA T, TAKIDO J, YOKOGOSHI H. Time-dependent Changes of Amino Acids in the Serum, Liver, Brain and Urine of Rats Administered with Theanine. Bioscience, Biotechnology, and Biochemistry. 1999;63(4):615-618.
Yokogoshi H, Kobayashi M, Mochizuki M, Terashima T. Effect of Theanine, r-Glutamylethylamide, on Brain Monoamines and Striatal Dopamine Release in Conscious Rats. Neurochem Res. 1998;23(5):667-673.
KAKUDA T, NOZAWA A, SUGIMOTO A, NIINO H. Inhibition by Theanine of Binding of [3H]AMPA, [3H]Kainate, and [3H]MDL 105,519 to Glutamate Receptors. Bioscience, Biotechnology, and Biochemistry. 2002;66(12):2683-2686.
Kimura K, Ozeki M, Juneja LR, Ohira H. l-Theanine reduces psychological and physiological stress responses. Biological Psychology. 2007;74(1):39-45.
Lu K, Gray MA, Oliver C, et al. The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans. Human Psychopharmacology: Clinical and Experimental. 2004;19(7):457-465.
Chihara K, Kashio Y, Kita T, et al. L-Dopa Stimulates Release of Hypothalamic Growth Hormone-Releasing Hormone in Humans. None. 1986;62(3):466-473.
Boyd AE, Lebovitz HE, Pfeiffer JB. Stimulation of Human-Growth-Hormone Secretion by L-Dopa. New England Journal of Medicine. 1970;283(26):1425-1429.
Matsui N, Takahashi K, Takeichi M, et al. Magnolol and honokiol prevent learning and memory impairment and cholinergic deficit in SAMP8 mice. Brain Research. 2009;1305:108-117.
Watanabe K, Watanabe HY, Goto Y, Yamamoto N, Yoshizaki M. Studies on the Active Principles of Magnolia Bark. Centrally Acting Muscle Relaxant Activity of Magnolol and Honokiol. The Japanese Journal of Pharmacology. 1975;25(5):605-607.
Ikarashi Y, Yuzurihara M, Sakakibara I, Nakai Y, Hattori N, Maruyama Y. Effects of the Extract of the Bark of Magnolia obovata and its Biphenolic Constituents Magnolol and Honokiol on Histamine Release from Peritoneal Mast Cells in Rats. Planta Med.
Hamasaki Y, Kobayashi I, Zaitu M, et al. Magnolol Inhibits Leukotriene Synthesis in Rat Basophilic Leukemia-2H3 Cells. Planta Med. 1999;65(3):222-226.
Lin Y-R, Chen H-H, Lin Y-C, Ko C-H, Chan M-H. Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain. Journal of Biomedical Science. 2009;16(1):94.
Alexeev M, Grosenbaugh DK, Mott DD, Fisher JL. The natural products magnolol and honokiol are positive allosteric modulators of both synaptic and extra-synaptic GABAA receptors. Neuropharmacology. 2012;62(8):2507-2514.
Chung Leung W, Zheng H, Huen M, Lun Law S, Xue H. Anxiolytic-like action of orally administered dl-tetrahydropalmatine in elevated plus-maze. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2003;27(5):775-779.
Liu Y-Y, Wang T-X, Zhou J-C, Qu W-M, Huang Z-L. Dopamine D1 and D2 receptors mediate analgesic and hypnotic effects of l-tetrahydropalmatine in a mouse neuropathic pain model. Psychopharmacology. 2019;236(11):3169-3182.
Nielsen FH, Johnson LK, Zeng H. Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep. Magnesium Research. 2010;23(4):158-168.1.
Serum magnesium level and sleep behavior of newborn infants. European Journal of Pediatrics, 134(3), 239\u2013243
Oral Mg2+ Supplementation Reverses Age-Related Neuroendocrine and Sleep EEG Changes in Humans. Pharmacopsychiatry, 35(4), 135\u2013143 | 10.1055\/s-2002-33195
Effects of a Magnesium Deficient Diet on Sleep Organization in Rats. Neuropsychobiology, 27(4), 237\u2013245
Chollet D, Franken P, Raf?n Y, et al. Magnesium Involvement in Sleep: Genetic and Nutritional Models. Behavior Genetics. 2001;31(5):413-425.
Chollet D, Franken P, Raffin Y, Malafosse A, Widmer J, Tafti M. Blood and brain magnesium in inbred mice and their correlation with sleep quality. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2000;279(6):R2173-R2178.
Brzezinski A. Melatonin in Humans. Epstein FH, ed. N Engl J Med. 1997;336(3):186-195.
Lieberman HR, Waldhauser F, Garfield G, Lynch HJ, Wurtman RJ. Effects of melatonin on human mood and performance. Brain Research. 1984;323(2):201-207.
Perry E, Walker M, Grace J, Perry R. Acetylcholine in mind: a neurotransmitter correlate of consciousness? Trends in Neurosciences. 1999;22(6):273-280.
Solms M. Dreaming and REM sleep are controlled by different brain mechanisms. BEHAVIORAL AND BRAIN SCIENCES. 2000:8.
Wamsley EJ, Stickgold R. Dreaming and offline memory processing. Current Biology. 2010;20(23):R1010-R1013.
Lau H, Alger SE, Fishbein W. Relational Memory: A Daytime Nap Facilitates the Abstraction of General Concepts. PLOS ONE. 2011;6(11):e27139.
Lee AK, Wilson MA. Memory of Sequential Experience in the Hippocampus during Slow Wave Sleep. Neuron. 2002;36(6):1183-1194.
Fosse MJ, Fosse R, Hobson JA, Stickgold RJ. Dreaming and Episodic Memory: A Functional Dissociation? Journal of Cognitive Neuroscience. 2003;15(1):1-9.
Wamsley EJ. Dreaming and Offline Memory Consolidation. Curr Neurol Neurosci Rep. 2014;14(3):433.
<\/SPAN><\/P><\/SPAN>","gtin12":"682863455489","image":["https:\/\/siteimgs.com\/10017\/item\/glaxon-sedative-grape-dra_2736-0.jpg"],"brand":"Glaxon","url":"https:\/\/www.dpsnutrition.net\/i\/29977\/glaxon-sedative-grape-drank-42-servings.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"39.99","url":"https:\/\/www.dpsnutrition.net\/i\/29977\/glaxon-sedative-grape-drank-42-servings.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Glaxon Tranquility Just Grape - 21 Servings","sku":"GN042","description":"
Ever feel like your pre-workout is lasting a little too long from your evening workout? Maybe if you had something to take the edge off, you could actually get to sleep on time. This is where Tranquility does the most work, by being designed to bring those energy levels back down so you can get the right amount of sleep you need to properly recover.<\/p>\r\n
Tranquility works mostly by providing the “inhibitory” (as opposed to excitatory) neurotransmitters L-Glycine and GABA. Some of these amino acids and extracts have a “secretagogue” effect in that they can elicit the release of growth hormone from the pituitary. Additionally, Tranquility provides other components like Theanine and Melatonin to reduce stress and promote sleep.<\/p>\r\n
Advanced users may mix 2 scoops (1 serving) with up to 500ml (~16oz) of water or beverage of choice. New users and those sensitive to sleep aids should start with 1 scoop (1\/2 serving), to assess their personal tolerance. Consume 30-60 minutes prior to desired bed time. Tastes best cold. Do not exceed 2 servings (4 scoops) per day.<\/p>\r\n\r\n
New Therapeutic Strategy for Amino Acid Medicine: Glycine Improves the Quality of Sleep. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1347861319305729
A Double-Blind, Randomized, Placebo-Controlled Crossover Clinical Study of the Effects of Alpha-s1 Casein Hydrolysate on Sleep Disturbance. https:\/\/www.mdpi.com\/2072-6643\/11\/7\/1466
GABA and l-theanine mixture decreases sleep latency and improves NREM sleep. https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13880209.2018.1557698
Tetrahydropalmatine promotes myoblast differentiation through activation of p38MAPK and MyoD. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X14019354
Non-cholinergic Effects of Huperzine A: Beyond Inhibition of Acetylcholinesterase. https:\/\/link.springer.com\/article\/10.1007\/s10571-007-9163-z<\/p>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>","gtin12":"850016284754","image":["https:\/\/siteimgs.com\/10017\/item\/tgrape-540x_1612546265-0.jpg"],"brand":"Glaxon","url":"https:\/\/www.dpsnutrition.net\/i\/30600\/glaxon-tranquility-just-grape-21-servings.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"44.99","url":"https:\/\/www.dpsnutrition.net\/i\/30600\/glaxon-tranquility-just-grape-21-servings.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Glaxon Tranquility Midnight Cherry - 21 Servings","sku":"GN041","description":"
Ever feel like your pre-workout is lasting a little too long from your evening workout? Maybe if you had something to take the edge off, you could actually get to sleep on time. This is where Tranquility does the most work, by being designed to bring those energy levels back down so you can get the right amount of sleep you need to properly recover.<\/p>\r\n
Tranquility works mostly by providing the “inhibitory” (as opposed to excitatory) neurotransmitters L-Glycine and GABA. Some of these amino acids and extracts have a “secretagogue” effect in that they can elicit the release of growth hormone from the pituitary. Additionally, Tranquility provides other components like Theanine and Melatonin to reduce stress and promote sleep.<\/p>\r\n
Advanced users may mix 2 scoops (1 serving) with up to 500ml (~16oz) of water or beverage of choice. New users and those sensitive to sleep aids should start with 1 scoop (1\/2 serving), to assess their personal tolerance. Consume 30-60 minutes prior to desired bed time. Tastes best cold. Do not exceed 2 servings (4 scoops) per day.<\/p>\r\n\r\n
New Therapeutic Strategy for Amino Acid Medicine: Glycine Improves the Quality of Sleep. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1347861319305729
A Double-Blind, Randomized, Placebo-Controlled Crossover Clinical Study of the Effects of Alpha-s1 Casein Hydrolysate on Sleep Disturbance. https:\/\/www.mdpi.com\/2072-6643\/11\/7\/1466
GABA and l-theanine mixture decreases sleep latency and improves NREM sleep. https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13880209.2018.1557698
Tetrahydropalmatine promotes myoblast differentiation through activation of p38MAPK and MyoD. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X14019354
Non-cholinergic Effects of Huperzine A: Beyond Inhibition of Acetylcholinesterase. https:\/\/link.springer.com\/article\/10.1007\/s10571-007-9163-z<\/p>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>","gtin12":"850016284778","image":["https:\/\/siteimgs.com\/10017\/item\/tmc-540x_1612546229-0.jpg"],"brand":"Glaxon","url":"https:\/\/www.dpsnutrition.net\/i\/30599\/glaxon-tranquility-midnight-cherry-21-servings.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"44.99","url":"https:\/\/www.dpsnutrition.net\/i\/30599\/glaxon-tranquility-midnight-cherry-21-servings.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Glaxon Tranquility Watermelon - 21 Servings","sku":"GN043","description":"
Ever feel like your pre-workout is lasting a little too long from your evening workout? Maybe if you had something to take the edge off, you could actually get to sleep on time. This is where Tranquility does the most work, by being designed to bring those energy levels back down so you can get the right amount of sleep you need to properly recover.<\/p>\r\n
Tranquility works mostly by providing the “inhibitory” (as opposed to excitatory) neurotransmitters L-Glycine and GABA. Some of these amino acids and extracts have a “secretagogue” effect in that they can elicit the release of growth hormone from the pituitary. Additionally, Tranquility provides other components like Theanine and Melatonin to reduce stress and promote sleep.<\/p>\r\n
Advanced users may mix 2 scoops (1 serving) with up to 500ml (~16oz) of water or beverage of choice. New users and those sensitive to sleep aids should start with 1 scoop (1\/2 serving), to assess their personal tolerance. Consume 30-60 minutes prior to desired bed time. Tastes best cold. Do not exceed 2 servings (4 scoops) per day.<\/p>\r\n\r\n
New Therapeutic Strategy for Amino Acid Medicine: Glycine Improves the Quality of Sleep. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1347861319305729
A Double-Blind, Randomized, Placebo-Controlled Crossover Clinical Study of the Effects of Alpha-s1 Casein Hydrolysate on Sleep Disturbance. https:\/\/www.mdpi.com\/2072-6643\/11\/7\/1466
GABA and l-theanine mixture decreases sleep latency and improves NREM sleep. https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13880209.2018.1557698
Tetrahydropalmatine promotes myoblast differentiation through activation of p38MAPK and MyoD. https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X14019354
Non-cholinergic Effects of Huperzine A: Beyond Inhibition of Acetylcholinesterase. https:\/\/link.springer.com\/article\/10.1007\/s10571-007-9163-z<\/p>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>","gtin12":"850016284761","image":["https:\/\/siteimgs.com\/10017\/item\/twtm-540x_1612546190-0.jpg"],"brand":"Glaxon","url":"https:\/\/www.dpsnutrition.net\/i\/30601\/glaxon-tranquility-watermelon-21-servings.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"44.99","url":"https:\/\/www.dpsnutrition.net\/i\/30601\/glaxon-tranquility-watermelon-21-servings.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Hi Tech Pharmaceuticals Melatonin 10 Mg - 60 Tab","sku":"HT158","description":"
Melatonin supplement facts<\/DIV><\/DIV>
Take 1 tablet prior to bedtime<\/P>\r\n
The marketing used by supplement companies to promote their supplements to the public (particularly the more aggressive types of dietary supplements) is usually packed with all kinds of hype about their products being \"novel,\" \"revolutionary,\" \"ground-breaking,\" \"cutting-edge,\" \"earth-shattering,\" ...whatever. Unfortunately, and at the expense of an often naive, emotionally-charged, consuming public that wants to believe when it comes to products that are supposed to radically change the way they look and feel (self esteem boosters), very seldom does a product come along that deserves such accolades. In reality, the vast majority of these types of products are just some sort of attempt to reinvent the wheel or, more accurately described (especially when it comes to sports nutrition supplements), a floundering attempt to reinvent a broken wheel.<\/SPAN><\/P>\r\n
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The marketing used by supplement companies to promote their supplements to the public (particularly the more aggressive types of dietary supplements) is usually packed with all kinds of hype about their products being \"novel,\" \"revolutionary,\" \"ground-breaking,\" \"cutting-edge,\" \"earth-shattering,\" ...whatever. Unfortunately, and at the expense of an often naive, emotionally-charged, consuming public that wants to believe when it comes to products that are supposed to radically change the way they look and feel (self esteem boosters), very seldom does a product come along that deserves such accolades. In reality, the vast majority of these types of products are just some sort of attempt to reinvent the wheel or, more accurately described (especially when it comes to sports nutrition supplements), a floundering attempt to reinvent a broken wheel.<\/SPAN><\/P>\r\n
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The marketing used by supplement companies to promote their supplements to the public (particularly the more aggressive types of dietary supplements) is usually packed with all kinds of hype about their products being \"novel,\" \"revolutionary,\" \"ground-breaking,\" \"cutting-edge,\" \"earth-shattering,\" ...whatever. Unfortunately, and at the expense of an often naive, emotionally-charged, consuming public that wants to believe when it comes to products that are supposed to radically change the way they look and feel (self esteem boosters), very seldom does a product come along that deserves such accolades. In reality, the vast majority of these types of products are just some sort of attempt to reinvent the wheel or, more accurately described (especially when it comes to sports nutrition supplements), a floundering attempt to reinvent a broken wheel.<\/SPAN><\/P>\r\n
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The marketing used by supplement companies to promote their supplements to the public (particularly the more aggressive types of dietary supplements) is usually packed with all kinds of hype about their products being \"novel,\" \"revolutionary,\" \"ground-breaking,\" \"cutting-edge,\" \"earth-shattering,\" ...whatever. Unfortunately, and at the expense of an often naive, emotionally-charged, consuming public that wants to believe when it comes to products that are supposed to radically change the way they look and feel (self esteem boosters), very seldom does a product come along that deserves such accolades. In reality, the vast majority of these types of products are just some sort of attempt to reinvent the wheel or, more accurately described (especially when it comes to sports nutrition supplements), a floundering attempt to reinvent a broken wheel.<\/SPAN><\/P>\r\n
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The marketing used by supplement companies to promote their supplements to the public (particularly the more aggressive types of dietary supplements) is usually packed with all kinds of hype about their products being \"novel,\" \"revolutionary,\" \"ground-breaking,\" \"cutting-edge,\" \"earth-shattering,\" ...whatever. Unfortunately, and at the expense of an often naive, emotionally-charged, consuming public that wants to believe when it comes to products that are supposed to radically change the way they look and feel (self esteem boosters), very seldom does a product come along that deserves such accolades. In reality, the vast majority of these types of products are just some sort of attempt to reinvent the wheel or, more accurately described (especially when it comes to sports nutrition supplements), a floundering attempt to reinvent a broken wheel.<\/SPAN><\/P>\r\n
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Reduce Anxiety & Tension During Times of High Stress*
Promote Deep Sleep & Restore Healthy Sleep Patterns*
Aid in Immune System Health
Boost Metabolism and Recovery
RelaXitrol is an All Natural, Non-Habit Forming Formula*<\/P><\/DIV><\/SPAN>","gtin12":"764779302016","image":["https:\/\/siteimgs.com\/10017\/item\/relaxitrol_1604959646-0.jpg"],"brand":"Metabolic Nutrition","url":"https:\/\/www.dpsnutrition.net\/i\/27567\/metabolic-nutrition-relaxitrol-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"29.99","url":"https:\/\/www.dpsnutrition.net\/i\/27567\/metabolic-nutrition-relaxitrol-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Now Foods Melatonin 10 Mg Extra Strength - 100 Cap","sku":"NO516","description":"
Melatonin 10 mg Extra Strength - 100 Veg Capsules<\/SPAN><\/H1><\/DIV>
Gastrointestinal Support*
A Dietary Supplement
Vegetarian\/Vegan<\/SPAN><\/DIV>
Servings Per Container: 100
Amount Per Serving % Daily Value*<\/SPAN><\/P>
\u2020 Daily Value not established.<\/SPAN><\/P>
Cellulose Powder, Cellulose (capsule) and Stearic Acid (vegetable source).<\/SPAN><\/P>