Chemix










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Cortibloc is a premium cortisol manager, blocker and fat burner with proven metabolism boosting support. This product not only helps reduce cortisol levels but aids in relieving stress that makes you body want to retain unwanted fat. Cortibloc contains ultra potent adaptogens allowing your body to become more resistant to stress inducing forces. <\/span><\/p>\r\n Training hard is a key component in building a dense muscular physique but when the body encounters stress or does not get adequate rest the central nervous system (CNS) becomes fatigued. Over time your body will respond to stress and lack of rest by creating fat deposits in response to your hormones being under stress.<\/span><\/p>\r\n CHEMIX ENERGY (SCIENCE BASED ENERGY FORMULA) FORMULATED BY THE GUERRILLA CHEMIST<\/p>\r\n <\/p>\r\n HOW DOES CHEMIX ENERGY WORK?<\/p>\r\n B-Phenylethylamine:<\/p>\r\n Phenylethylamine, or more commonly known as PEA, is the chemical backbone structure for many natural and prescription central nervous stimulants. PEA is found naturally in a variety of botanicals including Leguminosae and even chocolate. Your body even synthesizes it via bacteria from the amino L-phenylalanine. PEA falls under the category of trace amines can help your body release dopamine and serotonin, 2 neurotransmitters responsible for “feeling good” and “pleasure” by binding to the Trace amine associated receptor(TAAR). It is here where it can inhinit the reuptake of dopamine, serotonin and norepinephrine. PEA is missing the alpha carbon that would 1)protect it from the enzyme that breaks it down Mono Amine oxidase, and 2)would make it the chemical structure of amphetamine. Many pharmaceuticals were modeled after PEA that aid in ADHD, depression and much more. PEA as a supplement hits you hard and hits you quickly. That’s why I front loaded ENERGY with 500mg of it for that initial euphoric and stimulant rush.<\/p>\r\n Catuabua Bark Extract<\/p>\r\n Catuabua Bark Extract(std to 30% polyphenols): Catuaba (Trichilium catigua) has been used in traditional Brazilian medicine for its antidepressant and memory-stimulant properties(as well as libido). Catuaba Bark works mostly on modulating dopamine, which users report improved mood, enhanced cognition and focus, as expected. Remember, dopamine is released and reuptake is blocked in medications for ADHD, so this makes sense. According to the research, Catuaba not only boosts dopamine release and inhibits its transport\/reuptake, it also increases sensitivity of your D1 dopamine receptor. It’s also been shown to increase acetylcholine via acting as a mild acetylcholinesterase(enzyme that breaks down acetylcholine) inhibitor. Some research even suggests that it can increase the release and inhibit the reuptake of serotonin, as well. However, its mostly dopaminergic which is why it’s in this formula. It also has neuroprotective properties against oxidative stress. This compound is a superstar ingredient that not only will give you plenty of energy and dopamine, but focus, as well.<\/p>\r\n <\/p>\r\n Caffeine Anhydrous\/Caffeine Citrate: This formula contains a blend of caffeine anhydrous and citrate. Caffeine, a trimethylxanthine, in general is an adenosine antagonist meaning it blocks the sleepiness action of adenosine. This is what causes the alert feeling you get from caffeine. Caffeine citrate(approximately 51% caffeine) seems to hit more quickly vs its’ anhydrous counterpart, a very noticeable effect, however it has a much longer half-life compared to anhydrous. I am a big fan of the different time-releases of caffeine so it all doesn’t hit you at once. I purposely made the Nootropic caffeine-free so that one can add his\/her own custom amount of caffeine. ENERGY has a total of 267mg of caffeine from the 2 sources, not to overwhelm the other stimulants inside this incredible formula.<\/p>\r\n Source: Cova, I., Leta, V., Mariani, C. et al. Exploring cocoa properties: is theobromine a cognitive modulator?. Psychopharmacology 236, 561–572 (2019).<\/p>\r\n Hordenine HCL<\/p>\r\n Hordenine HCL: Hordenine is often mislabeled as a stimulant based off its structure, but it’s actually a mono amine oxidase-B inhibitor. Commonly known as N,N-tyramine, one could see how it can be confused with a PEA derivative. However, as we spoke earlier about monoamine oxidase being the enzyme that breaks down PEA and monoamines like dopamine, serotonin and norepinephrine, it is important to include such a compounds in order to increase the duration and effect of these stimulants. Specifically, monoamine oxidase-B is responsible for prolonging dopamine, one of the monoamines that PEA and Catuabua Bark releases and blocks the reuptake of. Hordenine at this high of a dose (150mg) is able to extend the active life of PEA and Catuabua’s dopamine release. Most companies use hordenine completely incorrectly or at too low a dose to be effective. Not me.<\/p>\r\n N,N-Dimethylphenylethylamine Citrate<\/p>\r\n N,N-dimethylphenylethylamine citrate: One of the strongest PEA derivatives that is legally able to be used in supplements, N,N-dimethylphenylethylamine citrate has the PEA backbone but with one crucial difference: it contains gemini methyl groups in the Nitrogen atom of the amine group. This allows it to last longer in the body by sterically hindering the metabolism from monoamine oxidase. The other great thing about having 2 methyl groups attached to the amine is that it makes the compound much more lipophilic, meaning it can cross the blood-brain barrier much more easily vs PEA. This means that more of the compound will actually get to where it needs to be in order to release dopamine and give you a rush of energy. This will have a similar effect as PEA, but should last longer and hit slightly harder!<\/p>\r\n N-Isopropylnorsynephrine<\/p>\r\n N-isopropylnorsynephrine: A newer stimulant to hit the market that is based-ff the ever popular synephrine stimulant, N-isoprpylnorsynephrine has an isopropyl group attached to the Nitrogen amine in order to make its effects last even longer. Synephrine is already a powerful stimulant, but like we spoke about earlier it can be quickly metabolized by our monoamine oxidase enzymes. Luckily, an isopropyl group is larger and more bulky compared to just 2 methyl groups, so only a very small amount Is needed to supply you with HOURS of energy! Synephrine also has the PEA background, and is very similar to tyramine, with only an hydroxyl group at the beta position. This allows for more tightly binding to your beta-2 adreno agonist receptors, the ones that BURN FAT. N-isopropylnorsynephrine also contains this hydroxyl group and has been shown to burn fat and stimulate your Beta-2 adreno receptors to the legal limit.<\/p>\r\n <\/p>\r\n Chemix GDA is an ultra-premium Glucose Disposal Agent designed to improve insulin sensitivity, shuttles carbohydrates into your cells for maximum nutrient partitioning, aids in maintaining healthy glucose levels, and increases glycogen storage to unseen levels. <\/SPAN><\/P> The advanced formula combines research-backed ingredients at clinical and efficacious doses to provide the most potent insulin mimetic available on the market today.<\/SPAN><\/P> Here is a complete breakdown for this extremely powerful formula:<\/SPAN><\/P> Chemix® GDA is a premium, multi-faceted glucose disposal agent product designed to help increase carbohydrate assimilation and metabolism, insulin sensitivity, and maintain healthy blood glucose levels. GDA allows your body to utilize the hormone insulin more efficiently, which can lead to gains in lean mass via increased glucose and amino acid uptake into your cells!<\/SPAN><\/P> Whether you\u2019re trying to gain 10lbs of muscle or lose 10lbs of fat, one key hormone can make or break your success: insulin. Insulin is a protein made up of 110 amino acids, and is secreted from the beta cells in the pancreas upon the intake of carbohydrates. Being a storage hormone, many consider insulin a double-edged sword. Insulin is the most anabolic hormone in the body as it\u2019s responsible for the uptake of glucose and amino acids to from glycogen and skeletal muscle tissue. Bodybuilders have put on slabs of lean muscle tissue by manipulating insulin, and it\u2019s speculated to be the reason why bodybuilders can compete heavier than ever before. But insulin also has a dark side- it can cause to the body to store large amounts of body fat, as well.<\/SPAN><\/P> Macronutrients are of the utmost importance when it comes to building muscle and burning fat, however if your body isn\u2019t utilizing them properly and efficiently you will fail at both. Inefficient nutrient partitioning normally results from the body not using insulin effectively. Here are some of the actions for which insulin is responsible: All dietary carbohydrates are broken down into the monomer glucose in the small intestine, which then is absorbed into the bloodstream. Once in the blood, glucose signals the pancreas to secrete insulin. Insulin will then bind to the insulin receptor (IR), where it triggers a series of reactions that ultimately <\/SPAN><\/P> leads to uptake of glucose and amino acids into the cell, glycogen synthesis, increased muscle protein synthesis, and glucose disposal (glycolysis), usually through the insulin receptor substrate\/phosphoinositide 3-kinase (IRS\/PI3K) pathway. GLUT4, a transporter needed to allow glucose to enter the cell, is translocated to the cell membrane via activation of the IR, and IRS pathway. Different pathways lead to different actions elicited by insulin, and herein lies how one can maximize the use of endogenous insulin to increase lean body mass or lose body fat.<\/SPAN><\/P> <\/SPAN> <\/P> Bitter Melon Extract(standardized to 10% bitters): Known as \"vegetable insulin,\u201d bitter melon is used to treat diabetes in many parts of the world, and in some places it\u2019s the only form of treatment. Bitter melon contains a variety of hypoglycemic herbs such as triterpenes, anthroquinones, and glucosinolates. The 3 most profound ones are charantin, polypeptide-p, and vicine. Studies have shown extracts from bitter melon to stimulate insulin release, increase skeletal muscle glucose uptake and utilization, suppress gluconeogenic enzymes, and preserve and regenerate beta cells(the cells that release insulin in the pancreas). There is even research on these compounds activating AMPK and PPARx, both of which help regulate energy expenditure in the body. <\/SPAN><\/P> Banaba leaf Extract(standardized to 25% tannins): Lagerstromemin speciosa , commonly known as banaba leaf, contains many compounds that can naturally help with blood sugar control. Most people assume it\u2019s the work of corsolic acid, for which most banaba supps are standardized. However, it\u2019s actually the gallotannins that are responsible the most for insulin memetic function. Specifically, Penta- O-galloyl-glucopyranose(PGG) was determined to have the strongest effect of the group. PGG was shown to significantly increase glucose transport into cells, both in vitro and in vivo. It also was shown to have an anti-adipogenic(inhibit fat cell production) effect, which many other glucose disposal agents do not possess(remember, insulin is adipogenic). Lagerstromemin was also identified to activate the insulin <\/SPAN><\/P> receptor(IR), one mechanism for lowering blood glucose. One of the other major mechanisms of action for banaba leaf is increasing expression and activation of GLUT-4, the transporter protein that allows glucose to be absorbed into cells. Interestingly, removing tannins from banaba extract eliminated all glucose transport activity(GLUT4), which also suggests that the tannins, not corsolic acid is responsible for the anti-diabetic effects. Another study showed that Lagerstromemin was about 54% as strong as insulin for glucose transport activity, which is pretty remarkable.<\/SPAN><\/P> <\/SPAN> <\/P> Alpha Lipoic Acid(yielding 150mg of R-ALA): Alpha Lipoic acid is a mitochondrial fatty acid with really interesting properties. It's been extensively studied for a multitude of benefits, but perhaps the most applicable are its use as an anti-oxidant and a tool to manage blood glucose levels and increase insulin sensitivity. ALA has been shown to reduce general biomarkers for oxidation, inflammatory cytosine and lipid peroxidation(generation of free radicals that can damage your cells). In a meta-analysis, ALA was shown to have a remarkable effect on blood glucose levels. It can increase expression of GLUT-4, the transport protein than shuttles glucose into your cells. It can also decrease the activity of phosphotyrosine phosphatase 1B(PTP1B), a negative regulator insulin response, as well as potentiating the insulin receptor substrate-1. All of these mechanisms can result in more carbohydrates going into your muscles instead of being stored as fat. R-ALA is one of the most important ingredients in GDA and works synergistically with the other ingredients to reduce blood glucose levels and increase glucose uptake in muscle cells. <\/SPAN><\/P> Gymnema Sylvestre Extract(standardized to 75% Gymnemic acids): Gymnema sylvestre(GS) is a natural antidiabetic herb that has been used to treat blood sugar ailments for centuries. GS contains triterpenoid saponins called gymnemic acids that stimulate the release of insulin from the pancreas, as well as increase glucose uptake in cells. GS extract has also been shown to lower LDL and vLDL(bad cholesterol), as well as increase HDL(good cholesterol). In addition, gymnema sylvestre extract has been shown to regenerate islet cells in your pancreas, which allows your body to regulate healthy insulin secretion and function. <\/SPAN><\/P> Super Berberine®(Berberine-Cyclodextrin complex): Berberine is one of the only supplements that has human data that shows efficacy on par with pharmaceuticals. It's main properties are activation of 5' adenosine monophosphate-activated protein kinase(AMPK), which leads to fatty acid oxidation, inhibition of cholesterol synthesis and lipogenesis, increases in muscle glucose uptake and insulin secretion(amongst other things). Focusing on muscle glucose uptake and insulin secretion, berberine was shown to very effective as a glucose disposal agent in serval studies. Berberine may increase glucose-stimulated insulin secretion and inhibit a-glucosidase activities, as well as promoting glucose uptake in cells. It works by increasing phosphorylation of the insulin receptor, insulin receptor substrate- 1, and protein kinase B. Berberine also inhibits the enzyme PTP1B, an enzyme that down regulates the insulin pathway which can also lead to insulin resistance. The main problem with Berberine is it has terrible bioavailability. Super Berberine is Berberine encased in beta-cyclodextrin, which has been shown to increase solubility by over double of free berberine in a simulated gastric environment. Super Berberine also contains sodium caprate, a fatty acid that increases diffusion of berberine through the epithelial cells in the intestine. <\/SPAN><\/P> Cinnulin PF®: Cinnulin PF® is a patented version of a 20:1 extract of Cinnamomum burmanni that contains high levels of water soluble double-linked procyanidin type-A polymers of flavanoids. Research shows that these polymers can increase autophosphorlyation of the insulin receptor-\u00df, insulin receptor substrate-1, and phosphatidylinositol 3-kinase, all of which activates the receptors and increases the ability for insulin to bind, as well as inhibits the enzyme phosphotyrosine phosphatase(PTP1B), which dephosphorlyates(inactivates) the insulin receptor.<\/SPAN><\/P> <\/SPAN> <\/P> By potentiating the insulin receptor, your body can use less insulin to absorb the same amount of glucose, thus increasing your insulin sensitivity. The polymers in Cinnulin PF® hav ealso been shown to increase GLUT-4 expression, the transporter molecule that brings glucose into cells. <\/SPAN><\/P> Chromium(III) polynicotinate: Although it has been known that chromium(III) (Cr) has positive effects on blood glucose control, the mechanism by which it does this has not been fully elucidated until <\/SPAN><\/P> recently. It was shown that insulin binds to the insulin receptor(IR) and then Cr binds in a second binding pocket, which increases IR activity anywhere from 3.5-8 fold, which has a downstream effect on multiple insulin-dependent pathways. Essentially, Chromium allows your body to use insulin more effectively due toits 2 binding sites on the IR. The polyniconinate chelate of Chromium has been found to be more bioavailable than other versions.<\/SPAN><\/P> <\/SPAN> <\/P> Chemix® GDA is a premium insulin memetic formula that combines 7 of the most well-studied and effective ingredients for maximizing the power of the anabolic hormone insulin! These carefully selected ingredients work with different mechanisms to allow your body to increase lean body mass by shuttling more glucose and amino acids into your cells, priming the perfect anabolic environment for growth. GDA can also help lower blood sugar levels, as well as increase insulin sensitivity, which may aid in fat loss! <\/SPAN><\/P> - The Guerrilla Chemist<\/SPAN><\/P> References: <\/SPAN><\/P> Klein G, Kim J, Himmeldirk K, Cao Y, Chen X. Antidiabetes and anti-obesity activity of Lagerstroemia human islets in vivo and in vitro.\" Phytotherapy Research 24.9 (2010): 1370-1376. <\/SPAN><\/P> Vincent, John B. \"Quest for the molecular mechanism of chromium action and its relationship to Shay, Kate Petersen, et al. \"Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential.\" Biochimica et Biophysica Acta (BBA)-General Subjects 1790.10 (2009): 1149-1160. Joseph, Baby, and D. Jini. \"Antidiabetic effects of Momordica charantia (bitter melon) and its Imparl-Radosevich, Jennifer, et al. \"Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: implications for cinnamon regulation of insulin signalling.\" Hormone Research in Paediatrics 50.3 (1998): 177-182. Leach, Matthew J. \"Gymnema sylvestre for diabetes mellitus: a systematic review.\" The Journal Akedo, Hitoshi, and Halvor N. Christensen. \"Nature of insulin action on amino acid uptake by the Zhang Y, Cui Y-L, Gao L-N, Jiang H-L. Effects of \u00df-cyclodextrin on the intestinal absorption of Zhang M, Lv X, Li J, Meng Z, Wang Q, Chang W, et al. Sodium caprate augments the Ziegenfuss, Tim N., et al. \"Effects of a water-soluble cinnamon extract on body composition and with high cholesterol diet.\" Int J Pharmacol 6.2 (2010): 138-141.<\/SPAN><\/P> <\/SPAN> <\/P>","gtin12":"860003220405","image":["https:\/\/siteimgs.com\/10017\/item\/chemix-gda-180-cap_2376-0.jpg"],"brand":"Chemix","url":"https:\/\/www.dpsnutrition.net\/i\/29518\/chemix-gda-180-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"42.94","url":"https:\/\/www.dpsnutrition.net\/i\/29518\/chemix-gda-180-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"Chemix Joint - 90 Cap","sku":"CMX24","description":" Cissus Quadrangularis (std. for 2.5% ketosteroids):<\/strong> <\/span>Cissus quadrangularis has been used in traditional Eastern medicine for hundreds of years to treat many ailments such as obesity and even as a natural anabolic, but specifically what caught my attention was its use for accelerating bone fracture healing rates and pain relief properties. Cissus quadrangularis is loaded with antioxidants, ascorbic acid, calcium, carotene\/carotenoids, resveratrol and triterpinoids. Many studies show that the main healing bioactives in cissus quadrangularis were its ketosteroid content found in the stem: onocer -7-ene-3α, 21-β-diol and onocer -7-ene-3β, 21α-diol. <\/p>\r\n The Guerrilla Chemist Has Spent Countless Hours Formulating The PERFECT Blend Of Ingredients To Help Increase Natural Testosterone Production As Well As Regulate Estrogen To Optimize Your Hormones So You Can Make Progress At A Pace You Have Never Experienced. Our Super Potent Anabolic Matrix Is The Answer To Improving Strength, Explosive Power, Enhanced Energy, Amazing Endurance, And A Great Way To Keep Estrogen Regulated To Mitigate Negative Side Effects And Regulate Unwanted Water Retention.<\/SPAN><\/P>\r\n Our New Anabolic Formulation Natabolic Contains Natural Phytoandrogens To Help Build Muscle Faster And Easier Than Ever Before. Natabolic Contains Premium Ingredients Like Byroviron, KSM-66, Laxogenin, Boron, And Arimistane That Not Only Aid In Boosting Testosterone But Also Help Regulate Estrogen To Give You A Harder And Drier Look Overall.<\/SPAN><\/P>\r\n Boosts Testosterone Levels Chemix CEO The Guerrilla Chemist is back with his long awaited Nootropic Formulation that not only decreases mental fatigue but increases cognition to enhance productivity and provide focus at levels you have never seen before.<\/p>\r\n Redefine your focus with our brand new caffeine free nootropic blend helping you to harness the power of incredible ingredients like Lions Mane Extract, Huperzine A, Ivy Leaf Extract, Kanna, and more which deliver mental acuity beyond your wildest imagination.<\/p>\r\n Nootropic is an ultra-premium, all-natural combination of 11 powerful ingredients designed to dramatically increase focus, enhance mood, and your ability to get things done! To understand how many of these ingredients work, you need a little background information on monoamines neurotransmitters. Monoamines neurotransmitters, such as serotonin, dopamine and norepinephrine contain 1 amine group(-NH 2 ), connected to an aromatic ring. All monoamines are derived from the amino acids phenylalanine, tyrosine and tryptophan and are dubbed “the feel good neurotransmitters.” The enzyme which breaks down all monoamines is known as monoamine oxidase (MAO). By inhibiting the enzyme MAO, these compounds and their effects can last longer in the body.<\/p>\r\n Serotonin is known as the “feel good” neurotransmitter and has been directly shown to elevate mood, cognition, learning and memory. Regulating serotonin is the main action by which most anti-depressant medications work. Increasing levels of serotonin, as well as blocking the re- uptake(usage) of serotonin is the mechanism of action for most prescription serotonin reuptake inhibitors (SRi). The cool thing is that there are many natural botanical that work very similarly.<\/p>\r\n Dopamine is another important monoamine that is a major part of your body’s reward- motivation system. It’s known as the “pleasure\/euphoric” chemical, and many pharmaceuticals revolve around the release and reuptake of dopamine, specifically ADHD medications. These medications work via blocking dopamine transporters or inhibiting reuptake. The reason why people need ADHD meds is because they do not produce high amounts of dopamine. By constantly looking around for outside stimuli, this causes a dopamine “fix” and their bodies will produce more dopamine. If you already have enough dopamine, releasing more and blocking its transport will dramatically increase your concentration.<\/p>\r\n Nootropic was designed to modulate serotonin and dopamine in a safe way in order to produce laser-like focus and concentration, being in a great mood and increase long-term learning and memory. Nootropic also increases levels of acetylcholine, the excitatory neurotransmitter in your brain that tells you to wake up. Acetylcholine has also been shown to increase focus, Kanna: Scelectium tortuosum AKA Kanna, is an herb that contains some very powerful nootropic and psychoactive alkaloids, including mesembrine. Kanna has been shown to interact with 77 different receptors in the body, but its main mechanism of action is acting as a natural serotonin reuptake inhibitor (SRi). Similarly to its pharmaceutical counterpart, elevating serotonin can cause mood enhancement and euphoria. Kanna is also a natural phosphodiesterase 4 inhibitor (PDE4i), which is responsible for wakefulness and long-term memory. Lastly, Kanna acts as a releasing agent, meaning it causes the release of dopamine and serotonin, which further enhances its effects (Serotonin)<\/p>\r\n Catuaba Bark Extract (30% polyphenols): Catuaba has been used in traditional Brazilian medicine for its antidepressant and memory-stimulant properties(as well as libido). Catuaba works mostly on modulating dopamine, which users report improved mood, enhanced cognition and focus, as expected. Remember, dopamine is released and reuptake is blocked in medications for ADHD, so this makes sense. According to the research, Catuaba not only boosts dopamine release and inhibits its transport\/reuptake, it also increases sensitivity of your D1 dopamine receptor. It’s also been shown to increase acetylcholine via acting as a mild acetylcholinesterase(enzyme that breaks down acetylcholine) inhibitor. Some research even suggests that it can increase the release and inhibit the reuptake of serotonin ,as well. However, its mostly dopaminergic. It also has neuroprotective properties against oxidative stress.<\/p>\r\n Ivy Leaf Extract (20% Hederagenin): Ivy leaf extract has been used for centuries in eastern medicine as cough\/cold agent. However, more recently the saponins found in the plant have had significant medicinal uses. Specifically, hederagenin is one of the main saponins that has bioactivity. It acts as a triple monoamine oxidase inhibitor (MAOi). Meaning, it can extend the active life of 3 of the main monoamines we discussed: serotonin, dopamine and norepinephrine. Taking ivy leaf extract may exhibit strong mood and cognitive enhancement, as well as slight euphoria. Ivy leaf has also been shown to be anti-neurogenerative.<\/p>\r\n Psoralea corylifolia (10:1 Extract): Psoralea coryifolia contains certain bioactive compounds like psoralidin and Δ 3 ,2-hydroxybakuchiol have been shown to possess serotonergic and dopaminergic activities, respectfully. This means that the seeds from this plant can act as a natural anti-depressant and mood enhancer, as well as increase focus and concentration.<\/p>\r\n CDP-Choline: Cytidine 5;-diphosphocholine, CDP-choline or citicoline is essential to the biosynthesis of phospholipids, like phosphatidylcholine. Once ingested, CDP-choline can easily cross the blood-brain barrier with its phospholipid backbone, where it can increase plasma levels of acetylcholine, as well as dopamine and norepinephrine. CDP-choline has been shown to increase learning and performance, along with being extremely safe.<\/p>\r\n N,N-dimethylphenylethylamine citrate and Higenamine: are derivatives of phenylethylamine (PEA). PEA, from a chemical structure standpoint, looks very similar to amphetamine. Because of this, these stimulants can elicit a dopamine release, that will further increase concentration when combined with some of the natural dopamine reuptake and monoamine inhibitors.<\/p>\r\n Huperzine A: Huperzine A is a natural acetylcholinesterase inhibitor, meaning it prevents the breakdown of acetylcholine in the brain. It is by far the strongest acetylcholinesterase enzyme inhibitor on the market. There are even studies showing it can be neuroprotective against beta- amyloid pigmentation, a protein that has direct links to Alzheimers disease, as well as protection against hydrogen peroxide- induced damage. This works synergistically with CDP-Choline to increase levels of acetylcholine.<\/p>\r\n Young, Simon N. \"How to increase serotonin in the human brain without drugs.\" Journal of psychiatry & neuroscience: JPN 32.6 (2007): 394. SLEEP is an all-natural, multifaceted sleep product designed to promote sleepiness and restful sleep to ensure maximum recovery. Quality sleep is one of the most important and essential actions your body needs to function properly. It is estimated that up to 33% of all adults do not get enough quality sleep. SLEEP is specifically designed to help fight off restlessness via different mechanisms of action, including inducing sleep and staying asleep.<\/P> HOW DOES CHEMIX SLEEP WORK? MagnaSleep? is an extremely potent form of magnolia bark extract(MBE), standardized for 90% of two powerful active phenolic compounds: magnolol and honokiol. These two bioactives also act on your GABAA receptors to help reduce anxiety and prepare your body for sleep. MBE has been used for thousands of years in Chinese and Japanese tradition medicine for help promote sleep and reduce anxiety. Magnolol and Honokiol both have very high binding affinity to your GABAA receptors, specifically interacting with the benzodiazepine binding site. This binding potentiates the sleep inducing-effect of baicalin. Since magnolol and honokiol can quickly be metabolized via glucuronidation, a hefty 25mg dose of BioPerine?(black pepper extract) was added to inhibit this process.<\/P> Cussonia zimmermannii is an African herb that has been studied for bioactive constituents that modulate your GABA receptors to induce sleep. The rootbark extract of C. zimmermannii has some very unique compounds known as polyacetylenes that have an extremely high affinity to GABAA receptors. These compounds have been shown to promote restfulness sleep, as well as staying asleep longer.<\/P> Hesperidin is one of the main bioactive compounds from citrus peel extract. It is a polyphenolic compound that has been shown to induce sleep, but does not act on the GABA receptor or benzodiazepine binding site. Studies show hesperidin interacts with your extracellular signal-regulated kinases 1\/2(ERK1\/2), located in the cortex and cerebellum. Hesperidin inhibits the activity of ERK1\/2, which may be linked to sedation. Studies show that hesperidin can induce sleepiness and enhance sleep, and may potentiate other sleep-promoting compounds that activate your GABAA receptors.<\/P> Apigenin is a polyphenolic flavonoid that is one of the most abundant and well-studied. Apigenin\u2019s mechanism of action is not directly on the GABA-benzodiazepine receptor, but does modulate its\u2019 activity. Studies show it has a synergistic effect when combined with GABAA agonists, like baicalin, magnolol and honokiol. It has been shown to reduce locomotor activity, which prevents restlessness and may help induce sleep. One study showed subjects taking apigenin slept for longer durations vs the placebo. Apigenin is also subject to glucuronidation, so absorption is critical. With 25mg of BioPerine? added to prevent this metabolism, you can be sure that the large dose of apigenin will be absorbed and utilized.<\/P> I formulated SLEEP because I have had sleeping issues all of my adult life. I have tried countless over-the-counter sleeping aids, melatonin, as well as 11 different pharmaceuticals. This combination of ingredients at clinical doses has dramatically improved my ability to fall asleep, my biggest issue, as well as stay asleep, my 2nd biggest issue. I scoured papers to look for natural sleep-enhancing compounds and I truly believe this formula will help anyone looking to get more restful sleep to help fully recover not only from exercise but from mental stress, as well.<\/P> References: <\/P> CHEMIX PURE WHEY ISOLATE PROTEIN WPI has been shown to massively increase muscle protein synthesis more than any other protein source!<\/p>\r\n But, that's not all. Each scoop of Chemix Protein Isolate contains 2g of the patented ingredient Velositol. Velositol is a complex of chromium picolinate, chromium histidinate and amylopectin. When combined with protein, it accelerates and boosts muscle protein synthesis (MPS) even further, which facilitates enhanced muscle growth, lean body mass, and quicker muscle recovery! Velositol is literally like doubling your protein dose due to its ability to increase absorption of protein and amino acids. The combination of chromium and amylopectin activates the insulin pathway to increase the uptake of amino acids into your muscle cells, one of the most effective pathways to building tons of muscle.<\/p>\r\n In a recent study, 15g of whey protein with 2g of Velositol outperformed the group taking either 15g of whey protein or taking 30g of whey protein! Velositol is literally like doubling your protein dose due to its ability to increase absorption of protein and amino acids. The subjects consumed the supplement immediately following exercise on training days and at the same time of day on non-training days. At 0, 4, and 8 weeks, the study researchers assessed body composition (4C via DEXA, Bod Pod, Bioimpedance), whole-body protein balance (15N-alanine), and upper\/lower body performance [one rep max (1RM) and repetitions to failure (RTF) on bench press and squat, vertical jump power]. The group that had the added Velositol outperformed each of the other groups in all the categories.<\/p>\r\n In summary, taking 2g of Velositol works even better than the group taking DOUBLE the amount of protein, increased lean mass, improved strength, and endurance.<\/p>\r\n 15g of WPI plus 2g of Velositol = 30g of WPI, less protein, more gains! <\/p>\r\n CHEMIX PURE WHEY ISOLATE PROTEIN WPI has been shown to massively increase muscle protein synthesis more than any other protein source!<\/p>\r\n But, that's not all. Each scoop of Chemix Protein Isolate contains 2g of the patented ingredient Velositol. Velositol is a complex of chromium picolinate, chromium histidinate and amylopectin. When combined with protein, it accelerates and boosts muscle protein synthesis (MPS) even further, which facilitates enhanced muscle growth, lean body mass, and quicker muscle recovery! Velositol is literally like doubling your protein dose due to its ability to increase absorption of protein and amino acids. The combination of chromium and amylopectin activates the insulin pathway to increase the uptake of amino acids into your muscle cells, one of the most effective pathways to building tons of muscle.<\/p>\r\n In a recent study, 15g of whey protein with 2g of Velositol outperformed the group taking either 15g of whey protein or taking 30g of whey protein! Velositol is literally like doubling your protein dose due to its ability to increase absorption of protein and amino acids. The subjects consumed the supplement immediately following exercise on training days and at the same time of day on non-training days. At 0, 4, and 8 weeks, the study researchers assessed body composition (4C via DEXA, Bod Pod, Bioimpedance), whole-body protein balance (15N-alanine), and upper\/lower body performance [one rep max (1RM) and repetitions to failure (RTF) on bench press and squat, vertical jump power]. The group that had the added Velositol outperformed each of the other groups in all the categories.<\/p>\r\n In summary, taking 2g of Velositol works even better than the group taking DOUBLE the amount of protein, increased lean mass, improved strength, and endurance.<\/p>\r\n 15g of WPI plus 2g of Velositol = 30g of WPI, less protein, more gains! <\/p>\r\n\r\n
<\/span><\/div>","gtin13":"0746477746026","image":["https:\/\/siteimgs.com\/10017\/item\/cmx052_1681739520-0.jpg"],"brand":"Chemix","url":"https:\/\/www.dpsnutrition.net\/i\/33024\/chemix-cortibloc-120-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"69.94","url":"https:\/\/www.dpsnutrition.net\/i\/33024\/chemix-cortibloc-120-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Chemix ENERGY - 60 Cap","sku":"CMX23","description":"
Chemix ENERGY is an ultra-premium, natural stimulant-based formula that gives users hours of endless energy. Whether it’s for the gym, work, gaming, or staying up, ENERGY combines 8 ingredients in efficacious and synergistic doses to make sure you are mentally firing on all cylinders. Each ingredient was chosen for a very specific purpose and dose to ensure that you get the maximum effect every time.<\/p>\r\n
Caffeine Anhydrous\/Caffeine Citrate: This formula contains a blend of caffeine anhydrous and citrate. Caffeine, a trimethylxanthine, in general is an adenosine antagonist meaning it blocks the sleepiness action of adenosine. This is what causes the alert feeling you get from caffeine. Caffeine citrate(approximately 51% caffeine) seems to hit more quickly vs its’ anhydrous counterpart, a very noticeable effect, however it has a much longer half-life compared to anhydrous. I am a big fan of the different time-releases of caffeine so it all doesn’t hit you at once. I purposely made the Nootropic caffeine-free so that one can add his\/her own custom amount of caffeine. ENERGY has a total of 267mg of caffeine from the 2 sources, not to overwhelm the other stimulants inside this incredible formula.<\/p>\r\n<\/p>","gtin12":"860003220474","image":["https:\/\/siteimgs.com\/10017\/item\/chemixenergy_1619807532-0.jpg"],"brand":"Chemix","url":"https:\/\/www.dpsnutrition.net\/i\/30868\/chemix-energy-60-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"44.99","url":"https:\/\/www.dpsnutrition.net\/i\/30868\/chemix-energy-60-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Chemix GDA - 180 Cap","sku":"CMX11","description":"
<\/SPAN><\/P>
The following is a mini crash course in how insulin works in the body: <\/SPAN><\/P>
speciosa. Evidence-Based Complementary and Alternative Medicine. 2007;4(4):401-7. 2. Al-Romaiyan, A., et al. \"A novel Gymnema sylvestre extract stimulates insulin secretion from <\/SPAN><\/P>
diabetes.\" Nutrition reviews 58.3 (2000): 67-72. <\/SPAN><\/P>
Kamenova, Petya. \"Improvement of insulin sensitivity in patients with type 2 diabetes mellitus
after oral administration of alpha-lipoic acid.\" HORMONES-ATHENS- 5.4 (2006): 251. <\/SPAN><\/P>
medicinal potency.\" Asian Pacific Journal of Tropical Disease3.2 (2013): 93-102. <\/SPAN><\/P>
Yina, Jun, Huili Xing, and Jianping Yeb. \"Efficacy of Berberine in Patients with Type 2 Diabetes.\"
Metabolism 57.5 (2008): 712-717. <\/SPAN><\/P>
of Alternative and Complementary Medicine 13.9 (2007): 977-983. <\/SPAN><\/P>
isolated diaphragm.\" Journal of Biological Chemistry 237.1 (1962): 118-122. <\/SPAN><\/P>
berberinehydrochloride, a P-glycoprotein substrate. International Journal of Biological Macromolecules. 2013 Aug;59:363\u201371. <\/SPAN><\/P>
hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis. Mol Cell Endocrinol. 2012 Nov 5;363(1-2):122\u201330. <\/SPAN><\/P>
features of the metabolic syndrome in pre-diabetic men and women.\" Journal of the International Society of Sports Nutrition 3.2 (2006): 45. 14. Rachh, P. R., et al. \"Antihyperlipidemic activity of Gymenma sylvestre R. Br. leaf extract on rats fed <\/SPAN><\/P>
HOW DOES CHEMIX JOINT WORK?<\/strong><\/h2>\r\n
However, newer research shows that it seems to be more of a cumulative effect from influencing early regeneration and faster uptake of minerals in bone cells. The ketosteroids still play a major part in healing, but it’s more like the “entourage effect.” A 2010 study showed a week faster healing period vs the placebo. This was attributed to the faster stimulation of fibroblasts(synthesizes collagen), chondroblasts(helps grow collagen) and bone cells. One study showed that collagen synthesis increased by 86%! I truly believe this is an extremely undervalued ingredient when it comes to joint and collagen supplementation. We used a whopping 750mg per serving!<\/p>\r\n
Pamlmitoylethanolamide:<\/strong> <\/span>Palmitoylethanolamide (PEA, a mouthful) is your body’s main naturally produced anti-inflammatory agent. PEA is one of many fatty acids that have the enthanolamide functional group attached to it. Its origins go back to an obscure study in the 1940s showing that PEA derived from purified egg yolks exhibited anti-inflammatory and anti-allergic properties. In 1964, it was first isolated in mammalian tissues and has over 350 studies since. PEA binds to the nuclear receptor, where it then elicits a variety of biological activities including fighting inflammation and pain. PEA has been extensively studied, including a 1970 study showing similar pain relief and joint improvement to aspirin. As far as managing pain and inflammation, PEA seems to have multiple mechanisms of action. One such mechanism is the inhibition pro-inflammatory compounds like TNF-alpha and histamine, as well as reducing cyclooxygenase-2(COX-2), which is how most over-the-counter NSAIDs(ibuprofen) work. In 1993, the Nobel Prize was given out to Lvei-Montalcini, who worked for almost 40 years trying to explain how PEA and inflammation were connected, by showing its positive role on NGF(nerve growth factor) and how mast cells(immune cells) could be modulated by PEA. In 1990, it was shown that PEA’s mechanism could also be explained by its high affinity for peroxisome proliferator-activated receptor alpha(PPAR-a).
In 2017, a meta-analysis involving 10 studies and 786 participants showed that subjects given PEA had significantly reduced pain levels. Daily doses ranged from 300-1200mg, with an average of 600mg.<\/p>\r\n
Tamarind Seed Extract (10:1 Tamarindus indica):<\/strong> <\/span>Tamarind seed extract is a more recently studied compound for helping with joint pain, movement and overall antiarthritic properties. Originally thought to solely work based on its high antioxidant content, newer research has shown that tamarind seed extract can lower levels of pro-inflammatory cytokines like interleukin-1B(IL-1B), TNF-a, IL-6, and COX-2. After running an High performance liquid chromatography(HPLC) on the seed extract, the main components were found to be Threo-Isocitric acid, Galactosyl glycerol, Procyanidin B2, Areccatannin B1, Catechin, Rutin and Embelin. In a 2015 study, arthritic rats given tamarind seed extract showed significantly improvement. Appendage swelling was dramatically down(comparable to rats given ibuprofen). Not only that, but metalloproteinases(MMPs) which are responsible for degradation of cartilage activity was significantly lowered in arthritic rats receiving tamarind seed extract, similar to pre-arthritic state. Oxidative stress levels were significantly lowered, not to mention glutathione(GSH), the body’s main antioxidant levels decline during levels of high oxidative stress. Tamarind seed extract was able to reverse the decline of GSH by 91%! This wonder seed is exactly what you need for lowering inflammation by multiple pathways.
CurcuWIN (Curcuma longa L. 20%):<\/strong> <\/span>Curcumin is one of the main curcuminoids found in turmeric. There have been hundreds of studies on curcumin and its positive effects on inflammation and joint improvement, not to mention antioxidant properties, heart health and overall health. Curcumin interacts with multiple inflammation pathways, specifically negating the action of IkB Kinase and nuclear factor-kappa B(NF-kB). It has the ability to help with both acute and chronic inflammation, via constantly inhibiting pro-inflammatory cytokines and downregulation of inflammatory enzymes like COX-2 and leukotrienes. It’s polyphenolic molecular shape allows it to be an excellent antioxidant and free radical scavenger. Curcumin has actually been shown to increase endogenous levels of antioxidants. Sounds amazing right? The downfall to curcumin and curcuminoids is their poor bioavailability. CurcuWIN\uf0d2 solves this problem using a proprietary delivery system called UltraSOL, which has been shown to increase the bioavailability of curcumin by 46X! Essentially, UltraSOL converts oil-soluble compounds(like curcumin) into more water dispersible compounds by using a polymer known as N-vinylpyrrolidone(NVP). NVP helps encase and disperse the curcuminoids to help them be more hydrophilic(water soluble). This allows your body to utilize much more of the active curcuminoids.<\/p>\r\n
Curcucmin<\/strong>
AprèsFlex Boswellia serrata gum resin std. for 20% AKBA:<\/strong> <\/span>The gum resin from Boswellia serrata has been used for centuries because its rich in terpene and triterpenic acids, known as boswellic acids that have anti-inflammatory enzyme properties. The most potent of them being 11-keto-\uf062-boswellic acid and 3-O-acetly-11-keto-\uf062-boswellic acid(AKBA). This compound specifically has a very strong ability to inhibit the enzyme 5-lipoxygenase(5-LOX), which is very proinflammatory. 5-LOX generates leukotrienes which can promote free radical damage and the migration of these compounds to inflamed areas. Another key benefit for boswellic acids in general is that they do not disrupt the synthesis of glycosaminoglycans like hyaluronic acid, chondroitin, heparin, keratin, ect, which can help with wound repair. Most over-the-counter NSAIDs do disrupt this and can actually hurt you in the long run and impair damage control. AprèsFlex\uf0d2 is standardized to 20% pure AKBA to get maximum results from the strongest component in the gum resin. Studies show that taking 1 serving of AprèsFlex\uf0d2 begins to work in as little as 5 days! No more taking big chalky pills for 30days to help.<\/p>\r\n
UC-II Standardized Chicken Cartilage(Providing 10mg Total Cartilage, Including Undenatured Type II Collagen):<\/strong> <\/span>Undenatured type-II collagen or UC-II has been extensively studies in humans to show improvements in almost all metrics used in testing(pain, flareups, joint mobility, ect). The key term here is UNDENATURED. This means the protein of the collagen is exactly has it is inside the body and includes all the necessary components like proteoglycans, glucosamine hyaluronic acid, and chondroitin sulfate. These make up the very basics of cartiliage and synovial fluid- the viscous, non-Newtonian fluid between your joints to reduce friction. Many human studies have all come to the same conclusion: supplementing with UC-II can significantly lower levels of inflammatory cytokines that have been linked to severity and incidence of signs of arthritic tendencies. Specifically, UC-II has been shown to lower TNF-alpha, IL-1Beta, and IL-6, all of which are prone to causing inflammation. But, helping increase\/preserve synovial fluid, that is something that can help your joints fight discomfort and keep them lubricated for either lifting weight in the gym or doing cardiovascular exercise.
Tetrahydrocurcumin:<\/strong> <\/span>We have already spoken about curcumin and its many benefits, we all as pitfalls. One major pitfall we spoke about was oral bioavailability, which I rectified using an highly-bioavailable form known as CurcuWin. However, we have yet to speak about one of the main metabolites of curcumin known as tetrahydrocurucmin. The “tetrahydro” means that there is a reduction in 2 double bonds on the molecule where 4 hydrogens are added in place. This dramatically improves the oral bioavailability of curcumin, especially in the intestinal tract. But, that’s not all. Tetrahydrocurcumin has been shown to have much higher antioxidant properties. Studies have shown it can lower cell damage via lipid peroxidation(damage from free radicals\/ROS). Tetrahydrocurcumin can also help to lower blood sugar levels and LDL(good cholesterol). In fact, in 2015, a meta-analysis was published comparing curcumin to tetrahydrocurcumin that included over 50 studies, both in vitro and in vivo. But perhaps more importantly, has been shown to hit different molecular targets than regular curcumin, which may have added benefits of its own. For example, vasoprotection seems to be a property of tetrahydrocurcumin vs curcumin, which as you guessed may be linked to helping control blood pressure.<\/p>\r\n<\/p>\r\n
References:<\/strong>
1. Stohs, Sidney J., and Sidhartha D. Ray. \"A review and evaluation of the efficacy and safety of Cissus quadrangularis extracts.\" Phytotherapy research 27.8 (2013): 1107-1114.
2. Jadhav, Atul N., et al. \"Ketosteroid standardized Cissus quadrangularis L. extract and its anabolic activity: Time to look beyond ketosteroid?.\" Pharmacognosy magazine 12.Suppl 2 (2016): S213.
3. Ghouse, Mr Mohammed Shakir. \"A pharmacognostical review on cissus quadrangularis linn.\" International Journal of Research 28 (2015).
4. Oben, Julius E., et al. \"The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress.\" Lipids in Health and Disease 6.1 (2007): 1-8.
5. Solorzano, Carlos, et al. \"Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.\" Proceedings of the National Academy of Sciences 106.49 (2009): 20966-20971.
6. Artukoglu, Bekir Berker, et al. \"Efficacy of palmitoylethanolamide for pain: a meta-analysis.\" Pain Physician 20.5 (2017): 353-362.
7. M Keppel Hesselink, Jan. \"New targets in pain, non-neuronal cells, and the role of palmitoylethanolamide.\" The Open Pain Journal 5.1 (2012).
8. Gabrielsson, Linda, Sofia Mattsson, and Christopher J. Fowler. \"Palmitoylethanolamide for the treatment of pain: pharmacokinetics, safety and efficacy.\" British journal of clinical pharmacology 82.4 (2016): 932-942.
9. Sundaram, Mahalingam S., et al. \"Tamarind seed (Tamarindus indica) extract ameliorates adjuvant-induced arthritis via regulating the mediators of cartilage\/bone degeneration, inflammation and oxidative stress.\" Scientific reports 5.1 (2015): 1-13.
10. Oliver, Jonathan Michael, et al. \"Novel form of curcumin attenuates performance decrements following muscle damaging exercise.\" The FASEB Journal 31 (2017): lb415-lb415.
11. Juturu, Vijaya, et al. \"Antioxidant Properties and Safety Evaluation of Curcumin (CurcuWINTM).\" The FASEB Journal 29 (2015): 924-5.
12. Jäger, Ralf, et al. \"Curcumin reduces muscle damage and soreness following muscle\u2010damaging exercise.\" The Faseb Journal 31 (2017): lb766-lb766.
13. Kanwar, Jagat R., et al. \"Cissus quadrangularis inhibits IL-1β induced inflammatory responses on chondrocytes and alleviates bone deterioration in osteotomized rats via p38 MAPK signaling.\" Drug design, development and therapy 9 (2015): 2927.
14. Lugo, James P., et al. \"Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers.\" Journal of the International Society of Sports Nutrition 10.1 (2013): 1-12.
15. Crowley, David C., et al. \"Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial.\" International journal of medical sciences 6.6 (2009): 312.
16. Bagchi, D., et al. \"Effects of orally administered undenatured type II collagen against arthritic inflammatory diseases: a mechanistic exploration.\" International journal of clinical pharmacology research 22.3-4 (2002): 101-110.
17. Aggarwal, Bharat B et al; “Curcumin differs from tetrahydrocurcumin for molecular targets, signaling pathways and cellular responses.”; Molecules (Basel, Switzerland); vol. 20,1; 185-205; 24 Dec. 2014;
18. Sandur, Santosh K., et al. \"Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism.\" Carcinogenesis 28.8 (2007): 1765-1773.
19. Sugiyama, Yosunori, Shunro Kawakishi, and Toshihiko Osawa. \"Involvement of the β-diketone moiety in the antioxidative mechanism of tetrahydrocurcumin.\" Biochemical pharmacology 52.4 (1996): 519-525.
20. Zhang, Zhen-Biao, et al. \"Curcumin’s metabolites, tetrahydrocurcumin and octahydrocurcumin, possess superior anti-inflammatory effects in vivo through suppression of TAK1-NF-κB pathway.\" Frontiers in pharmacology 9 (2018): 1181.<\/p>","gtin12":"860003220467","image":["https:\/\/siteimgs.com\/10017\/item\/57f3826c-cf8d-4f40-984b-e_1620664215-0.jpg"],"brand":"Chemix","url":"https:\/\/www.dpsnutrition.net\/i\/30908\/chemix-joint-90-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"41.98","url":"https:\/\/www.dpsnutrition.net\/i\/30908\/chemix-joint-90-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/OutOfStock"}},{"@type":"Product","name":"Chemix Natabolic - 240 Cap","sku":"CMX20","description":"
\r\n
\r\n
Decreases Unwanted Estrogen
Improves Energy & Endurance
Bolsters Strength
Enhances Overall Endurance<\/SPAN><\/P>\r\n
","gtin12":"860003220429","image":["https:\/\/siteimgs.com\/10017\/item\/natabolic_1602541883-0.jpg"],"brand":"Chemix","url":"https:\/\/www.dpsnutrition.net\/i\/30193\/chemix-natabolic-240-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"49.98","url":"https:\/\/www.dpsnutrition.net\/i\/30193\/chemix-natabolic-240-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Chemix Nootropic - 168 Cap","sku":"CMX21","description":"
HOW DOES CHEMIX NOOTROPIC WORK?<\/p>\r\n
learning and concentration.<\/p>\r\n
Lion’s Mane Extract: Lions mane is another powerful nootropic that has shown to improve memory and cognition, increase NGF, which can cause nerve regeneration, as well as decreased levels of beta-amyloid plaque. Lions mane also has anti-inflammatory and antioxidant properties. One human study showed improved memory and scores on cognitive tests. Lions mane also contains erinacine, which can increase dopamine levels and possibly mood enhancement. There is also an immune system boosting effect from the beta d-glucans, which can also improve gut health. Over 80% of your body’s serotonin is produced in the gut so it may help with serotonin release. This product contains 375mg of lions mane extract.<\/p>\r\n
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References:<\/p>\r\n
Tripp, Gail, and Jeff R. Wickens. \"Research review: dopamine transfer deficit: a neurobiological theory of altered reinforcement mechanisms in ADHD.\" Journal of child psychology and psychiatry 49.7 (2008): 691-704.
Martins, Nadini Oliveira, et al. \"Antioxidant, anticholinesterase and antifatigue effects of Trichilia catigua (catuaba).\" BMC complementary and alternative medicine 18.1 (2018): 172.
Campos, Maria M., et al. \"Antidepressant-like effects of Trichilia catigua (Catuaba) extract: evidence for dopaminergic-mediated mechanisms.\" Psychopharmacology 182.1 (2005): 45-53.
Viana, Alice F., et al. \"Antinociceptive activity of Trichilia catigua hydroalcoholic extract: new evidence on its dopaminergic effects.\" Evidence-Based Complementary and Alternative Medicine 2011 (2011).
Jin, Zeng-Liang, et al. \"The extracts of Fructus Akebiae, a preparation containing 90% of the active ingredient hederagenin: serotonin, norepinephrine and dopamine reuptake inhibitor.\" Pharmacology Biochemistry and Behavior 100.3 (2012): 431-439.
Zeng, Jia, et al. \"Current knowledge and development of hederagenin as a promising medicinal agent: a comprehensive review.\" RSC advances 8.43 (2018): 24188-24202.
Yi, Li-Tao, et al. \"Antidepressant-like effects of psoralidin isolated from the seeds of Psoralea corylifolia in the forced swimming test in mice.\" Progress in Neuro-Psychopharmacology and Biological Psychiatry 32.2 (2008): 510-519.
Zhao, G., et al. \"In vitro dopaminergic neuroprotective and in vivo antiparkinsonian-like effects of Δ 3, 2-hydroxybakuchiol isolated from Psoralea corylifolia (L.).\" Cellular and Molecular Life Sciences 66.9 (2009): 1617-1629.
Secades, Julio J., and G. Frontera. \"CDP-choline: pharmacological and clinical review.\" Methods and findings in experimental and clinical pharmacology 17 (1995): 1-54.
Wurtman, Richard J., et al. \"Effect of oral CDP-choline on plasma choline and uridine levels in humans.\" Biochemical pharmacology 60.7 (2000): 989-992.<\/p>","gtin12":"860003220436","image":["https:\/\/siteimgs.com\/10017\/item\/chemixnootropic_1607715116-0.jpg"],"brand":"Chemix","url":"https:\/\/www.dpsnutrition.net\/i\/30442\/chemix-nootropic-168-cap.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"44.99","url":"https:\/\/www.dpsnutrition.net\/i\/30442\/chemix-nootropic-168-cap.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Chemix Sleep - 90 Cap","sku":"CMX19","description":"<\/DIV>
Provides Incredible Rest
Aids With REM Sleep
No Hangover Effect
Boosts Overall Energy
Creates Better Daily Mood<\/P>
Assist Your Recovery And Induce Restfulness With The All New Chemix Ultra Premium Sleep Aid. The Guerrilla Chemist Has Gone Back To The Lab And Formulated Our First Ever Ultra Premium Sleep Aid Product. This One Of A Kind Formulation Will Turn Your Lights Out When It's Time To Get Your Rest. Chemix Sleep Will Provide The Best In Rest And Recovery With No Excess Hangover Leaving You Ready To Take On The Day With Plenty Of Energy And Focus.<\/P>
GABAiclin? is a trademarked extract of Scutellaria baicalensis, standardized for 30% of the main active baicalin. Baicalin is a positive allosteric agonist for your GABAA receptors. ?-aminobutyric acid, aka GABA is your main inhibitory neurotransmitter that essentially tells your brain it\u2019s time to get ready for sleep. Once baicalin binds to your GABAA receptor, it activates the receptor and elicits sedative, hypnotic, muscle relaxant and anxiolytic(anti-anxiety) properties. This is the same mechanism and receptor that a class of sleep medications known as benzodiazepines interacts with. Baicalin has been shown to increase slow-wave sleep(deep sleep), as well as REM(rapid eye movement) sleep. REM sleep is extremely valuable to your body, as it releases growth hormone(GH) to help aid in recovery.<\/P><\/DIV>
1. Chang HH, Yi PL, Cheng CH, et al. Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation. J Ethnopharmacol. 2011;135(2):359-368.
2. Shi, Yuan, et al. \"Herbal insomnia medications that target GABAergic systems: a review of the psychopharmacological evidence.\" Current Neuropharmacology 12.3 (2014): 289-302.
3. Ai, Jinglu, Xiaomei Wang, and Mogens Nielsen. \"Honokiol and magnolol selectively interact with GABAA receptor subtypes in vitro.\" Pharmacology 63.1 (2001): 34-41.
4. Squires, Richard F., et al. \"Honokiol and magnolol increase the number of [3 H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites.\" Neurochemical research 24.12 (1999): 1593-1602.
5. Chen, Chang-Rui, et al. \"Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, induces sleep via the benzodiazepine site of GABAA receptor in mice.\" Neuropharmacology 63.6 (2012): 1191-1199.
6. Senn, Martin W. Structures and evaluation of biologically active constituents of\" Cussonia Zimmermannii\" harms. Diss. University_of_Basel, 2006.
7. Mart\u00ednez, M. Cecilia, et al. \"Hesperidin, a flavonoid glycoside with sedative effect, decreases brain pERK1\/2 levels in mice.\" Pharmacology Biochemistry and Behavior 92.2 (2009): 291-296.
8. Fern\u00e1ndez, Sebasti\u00e1n P., et al. \"Synergistic interaction between hesperidin, a natural flavonoid, and diazepam.\" European journal of pharmacology 512.2-3 (2005): 189-198.
9. Fern\u00e1ndez, Sebasti\u00e1n, et al. \"Sedative and sleep-enhancing properties of linarin, a flavonoid-isolated from Valeriana officinalis.\" Pharmacology Biochemistry and Behavior 77.2 (2004): 399-404.
10. Salehi, Bahare, et al. \"The therapeutic potential of apigenin.\" International journal of molecular sciences 20.6 (2019): 1305.
11. Kim, Jae-Wook, et al. \"Enhancement of pentobarbital-induced sleep by apigenin through chloride ion channel activation.\" Archives of pharmacal research 35.2 (2012): 367-373.
Gazola, Andressa C., et al. \"Involvement of GABAergic pathway in the sedative activity of apigenin, the main flavonoid from Passiflora quadrangularis pericarp.\" Revista Brasileira de Farmacognosia 25.2 (2015): 158-163<\/P>
By The Guerilla Chemist
Chemix Protein is 100% Whey Protein Isolate(WPI), the gold standard of protein powders. WPI is an extremely high quality protein due to its excellent source of EAA\/BCAA and how quickly it breaks down in the body and starts building muscle.<\/p>\r\n
Increases MPS(doubles!) both from BCAA and insulin pathways
increases lean body mass gains
increases recovery
Doubles squat reps to failure (25 reps vs 14 reps with just protein)
Increases overall strength(43%) and power in all lifters<\/p>\r\n<\/p>","gtin12":"860007502644","image":["https:\/\/siteimgs.com\/10017\/item\/chemix-pro-pb_1677861343-0.jpg"],"brand":"Chemix","url":"https:\/\/www.dpsnutrition.net\/i\/32898\/chemix-whey-protein-isolate-wpi-chocolate-peanut.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"54.99","url":"https:\/\/www.dpsnutrition.net\/i\/32898\/chemix-whey-protein-isolate-wpi-chocolate-peanut.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@type":"Product","name":"Chemix Whey Protein Isolate (WPI) Vanilla - 2.3 Lb (30 Servings)","sku":"CMX29","description":"
By The Guerilla Chemist
Chemix Protein is 100% Whey Protein Isolate(WPI), the gold standard of protein powders. WPI is an extremely high quality protein due to its excellent source of EAA\/BCAA and how quickly it breaks down in the body and starts building muscle.<\/p>\r\n
Increases MPS(doubles!) both from BCAA and insulin pathways
increases lean body mass gains
increases recovery
Doubles squat reps to failure (25 reps vs 14 reps with just protein)
Increases overall strength(43%) and power in all lifters<\/p>\r\n<\/p>","gtin12":"860007502651","image":["https:\/\/siteimgs.com\/10017\/item\/chemix-pro-van_1677860728-0.jpg"],"brand":"Chemix","url":"https:\/\/www.dpsnutrition.net\/i\/32899\/chemix-whey-protein-isolate-wpi-vanilla-2.3-lb-30.htm","offers":{"@type":"Offer","priceCurrency":"USD","price":"54.99","url":"https:\/\/www.dpsnutrition.net\/i\/32899\/chemix-whey-protein-isolate-wpi-vanilla-2.3-lb-30.htm","itemCondition":"http:\/\/schema.org\/NewCondition","availability":"http:\/\/schema.org\/InStock"}},{"@context":"https:\/\/schema.org","@type":"WebSite","name":"DPS Nutrition","image":"https:\/\/siteimgs.com\/10017\/imgs\/04\/dpslogo_1595279419-0.jpg","url":"https:\/\/www.dpsnutrition.net\/","potentialAction":{"@type":"SearchAction","target":"https:\/\/www.dpsnutrition.net\/search?q={search_term_string}","query-input":"required name=search_term_string"},"sameAs":["https:\/\/www.facebook.com\/DPSNutrition","https:\/\/twitter.com\/DpsNutrition","https:\/\/instagram.com\/dpsnutrition"]},{"@context":"https:\/\/schema.org","@type":"Organization","url":"https:\/\/www.dpsnutrition.net\/","logo":"https:\/\/siteimgs.com\/10017\/imgs\/04\/dpslogo_1595279419-0.jpg","image":"https:\/\/siteimgs.com\/10017\/imgs\/04\/dpslogo_1595279419-0.jpg","name":"DPS Nutrition","legalName":"DPS Nutrition","telephone":"1-800-697-4969","address":{"@type":"PostalAddress","addressLocality":"Taylor","addressRegion":"PA","postalCode":"18517","streetAddress":"29 Stauffer Industrial Park"}}]}
Chemix