• Core Nutritionals 5-AT - 84 Cap

Core Nutritionals 5-AT - 84 Cap

Item #: CU057UPC: 850757001511
$29.99
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Enhance Your Vitality Now! Core Nutritionals 5-AT offers powerful cortisol suppression and anti-immunosuppressive benefits due to the potent metabolite androstenetriol derived from DHEA. Each serving provides 25mg of 5-Etioallocholen-3b,7b,17b-Triol, an effective compound key to muscle growth and immune function.
5-Etioallocholen-3b,7b,17b-triol

More commonly known as androstenetriol, 5-etioallocholen-3 beta-7 beta-17beta-triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex steroids such as testosterone and estrogen, up-regulating (increasing) immune response and countering the immunosuppressive actions of corticosteroids, and maybe the most impressive, directly and strongly suppressing the release of cortisol itself!

Though DHEA’s properties have been well-established and understood for decades, derivatives and metabolites of DHEA have more recently been the subject of research in animals and humans – demonstrating effects that are, at times, many orders of magnitude more significant than the parent compound (up to 100x as potent!).

Like DHEA, cortisol is one of the body’s most abundant and important endogenous steroids. While detailing in full the expansive list of cortisol’s functions is impossible, we can generally say that cortisol’s role in the human body is to break down bodily tissue and nutrients for the purpose of energy provision (to be catabolic), to act as an immunosuppressive, and to regulate blood sugar. Cortisol fulfills these functions by inducing gluconeogenesis (the breakdown of non-glucose intermediates, such as amino acids in muscle tissue, into glucose) and glycogenolysis (the breakdown of glycogen into glucose), inhibiting peripheral glucose utilization, and inhibiting cell lines critical to the body’s immune response.

In less complex terms, we can simply say that cortisol is responsible for inhibiting many of the processes that we as fitness enthusiasts want to start, and for starting many of the processes that we want to inhibit. Cortisol plays a role in:

  • Preventing our muscle cells from uptaking glucose (inducing insulin resistance).
  • Preventing muscle protein synthesis.
  • The breakdown of glycogen (the compound responsible for that 'full look').
  • Suppressing the immune processes involved in muscle growth.

While these are necessary functions, their overexpression is precisely the opposite of what we want – in fact, certain trials in humans have shown that an increase in plasma cortisol within the physiologic range increases proteolysis (breakdown of proteins) and degrades whole body amino acid synthesis! That is bad, bad news.

Enter DHEA and its metabolite, androstenetriol. In emerging animal literature, both androstenetriol and its metabolites have been shown to possess very potent anti-glucocorticoid activity – remembering that cortisol is the parent compound for this group – and anti-immunosuppressive actions in a number of different tissue types. In fact, androstenetriol is one of the most potent anti-glucocorticoids the body produces – exerting almost unbelievable effects in certain pro-inflammatory cell lines.

Supplement Facts
Serving size: 1 capsule
Servings per container: 84
 Amount per serving% Daily Value
5-Etioallocholen-3b,7b,17b-Triol25mg
Ingredients: Gelatin, Magnesium Stearate, Rice Flour
Notes: Take 1 capsule 2-3 times per day. For optimal results, take 1 capsule upon waking, 1 capsule midday, and 1 capsule before bed. Do not exceed 4 capsules in a 24 hour period. For best results, use for 4 to 8 weeks. Do not use for longer than 8 continuous weeks without taking a 4 week break.

Core Nutritionals 5-AT - 84 Cap Q&A

What is Core Nutritionals 5-AT?
Core Nutritionals 5-AT is a supplement designed to help with cortisol suppression and muscle growth through its potent compound androstenetriol.
What benefits does 5-AT provide?
5-AT provides benefits such as powerful cortisol suppression, anti-immunosuppressive actions, and aids muscle growth.
How much 5-Etioallocholen-3b,7b,17b-Triol is in each serving?
Each serving of Core Nutritionals 5-AT contains 25mg of 5-Etioallocholen-3b,7b,17b-Triol.
How does 5-AT affect cortisol levels?
5-AT contains androstenetriol, a metabolite known for its potent anti-glucocorticoid activity, which helps in effectively suppressing cortisol levels.
What is androstenetriol?
Androstenetriol is a potent metabolite derived from DHEA, known for its significant anti-glucocorticoid activity and anti-immunosuppressive properties.
Can 5-AT help with muscle growth?
Yes, 5-AT helps with muscle growth by countering cortisol's suppressive effects on muscle protein synthesis.
Is 5-AT suitable for fitness enthusiasts?
Definitely! 5-AT is specifically designed to cater to the needs of fitness enthusiasts by promoting muscle growth and overall vitality.
How does 5-AT impact the immune system?
5-AT helps in up-regulating immune response by countering the immunosuppressive actions of cortisol.
What role does DHEA play in 5-AT?
DHEA serves as the precursor for androstenetriol, the active compound in 5-AT, which provides the supplement's key benefits.
How are glucocorticoids affected by 5-AT?
5-AT's active compound, androstenetriol, significantly reduces the effects of glucocorticoids, thereby promoting muscle growth and reducing cortisol's catabolic actions.