The unique phosphate-bonded creatine in C.G.P. has an unparalleled advantage in its delivery by using an additional glycerol bond to facilitate rapid absorption. C.G.P. delivers a high energy boost to your ATP supply to help delay fatigue and maximize strength development.*
With more than 600 published studies backing its value for athletes and general fitness enthusiasts alike, creatine has long been one of the most popular sports supplement ingredients due to its well-established track record of safety and efficacy. While there are many forms of creatine, only C.G.P. has the unique double bonding of glycerol and phosphate to improve absorption, increase energy through enhanced ATP production, and provide better blood flow which increases vascularity and sustains harder muscle pumps. The superior absorption kinetics of C.G.P. means that there is no need for a loading phase and users will not experience bloating or cramping typically found in other creatines.*
Creatine is a nitrogenous organic acid that occurs naturally in the body and helps to supply energy to all cells in the body, primarily muscle. It increases energy by directly increasing the formation of adenosine triphosphate (ATP). Creatine is naturally produced in the human body from amino acids primarily in the kidney and liver. It is then transported through the blood for use by muscles. Approximately 95% of the human body’s total creatine is located in skeletal muscle. Creatine is not an essential nutrient, as it is manufactured in the human body from L-arginine, glycine, and L-methionine. It can also be provided as a supplement in one’s diet.*
How does Creatine function in the body?
Creatine, synthesized in the liver and kidney, is transported through the blood and taken up by tissues with high energy demands, such as the brain and skeletal muscle, through an active transport system. The concentration of ATP in skeletal muscle is usually 2-5 mM, which would result in a muscle contraction of only a few seconds. Fortunately, during times of increased energy demands, the phosphagen (or ATP/PCr) system rapidly resynthesizes ATP from ADP with the use of phosphocreatine (PCr) through a reversible reaction with the enzyme creatine kinase (CK). In skeletal muscle, PCr concentrations may reach 20-35 mM or more as it is marginally rate limited. Additionally, in most muscles, the ATP regeneration capacity of CK is very high and is therefore not a limiting factor. Although the cellular concentrations of ATP are small, changes are difficult to detect because ATP is continuously and efficiently replenished from the large pools of PCr and CK. Creatine has the ability to increase muscle stores of PCr, potentially increasing the muscle’s ability to resynthesize ATP from ADP to meet increased energy demands.*
How does C.G.P. work?
C.G.P. is already bonded to a "phosphate” donor making it highly usable due to it being absorbed in the active transport system and deposited directly into muscle tissue.
It is chemical structure is already in the PCr "phospho-creatine” state, so it is ready for use by the muscle.
Its "ready-state” as a PCr (phospho-creatine) structure makes it readily available for enzamatic reduction by CK (creatine kinase) to donate the phosphate directly to ATP cycle.
C.G.P. has to rate limit to the level it is absorbed into the muscle cell as it is already in the PCr (phospho-creatine) form, thus leading to higher endogeneous PCr levels than those seen with regular creatines.*
How does C.G.P. make you not retain water?
Water retention from regular creatine is very common. The reason for the water bloating is due to the degradation of creatine to creatinine, which is a toxin caused from the breakdown of creatine that circulates in the blood that needs to be filtered out by the kidneys. Regular creatine breaks down very rapidly into creatinine, even before it gets to the muscle. C.G.P. (Creatine Glycerol Phosphate) does not make you retain water weight (edema) because of these 4 main reasons:
C.G.P. is already bonded to phosphate, thus it is in the required and necessary PCr (phospho-creatine) state to prevent degradation from the creatine into creatinine.
C.G.P. active reversible reaction from the enzymatic process of creatine kinase makes the supply very efficient for replenishment of ATP, therefore eliminating degradation of creatine into creatinine.
C.G.P. can easily be replenished with phosphate bonds to continually replenish ATP levels.
C.G.P. is in the required PCr (phospho-creatine) chemical configuration and is not as rate-limited in the body as regular creatine. Therefore, the body can store and utilize greater concentrations of C.G.P. as opposed to regular creatine.*
Why am I not getting the same amount of scoops as servings per container stated?
Due to the fine pharmaceutical mesh size (particle size) of C.G.P., compression may occur from the vibration in shipping. Therefore, when scooping out the powder after it is compressed, a scoop may actually yield slightly more than the label indicates. It is recommended to shake the container to release the compression of the powder and restore it to its fluffy natural state. After doing this, every scoop should be a consistent 10 grams.
What is glycerol and why is it in C.G.P.?
Glycerol is a simple polyol compound that is central to all lipids known as triglycerides. It is a colorless, odorless, viscous liquid that is widely used in pharmaceutical formulations. Glycerol has three hydroxyl groups that are responsible for its solubility in water and its hygroscopic nature. It is this exact hygroscopic property that gives Gycerol it’s amazing hydration property in the muscle cell. Additionally, its chemical construction also lends itself to easily and quickly permeate the lipid by-layer of cell walls, thus easily and efficiently delivering water and C.G.P. into the muscle tissue, while removing waste byproducts from muscle metabolism.*
What is the purpose of the phosphates in C.G.P.?
The purpose of bonding "phosphates” to the creatine molecule is to provide the correct and biologically needed PCr (phospho-creatine) or creatine phosphate into muscle tissue to fuel the ATP cycle for sustained energy and muscle torque energy.*
Why does C.G.P. smell like sulfur or eggs?
Phosphates have a sulfur-like smell, but they exhibit no taste. Therefore, once mixed in water, there are no sensory issues to overcome.
Why is there a tingling feeling in the back of my throat when I drink C.G.P.?
The Alpha Lipoic Acid is contributing directly to this tingling feeling you have. We add Alpha Lipoic Acid to C.G.P. to control glucose levels and facilitate rapid production of gluconeogenisis (glycogen production) while facilitating rapid absorption of key electrolytes into muscle tissue.*
Is C.G.P. stable in water?
Yes, the phospho-creatine bond protects the creatine structure from degradation of the individual amino acids. This is not true of other "regular” creatines.*
What are the benefits of the Potassium, ALA, Magnesium, Calcium and Sodium?
These electrolytes assist in the electrolyte balance between the intracellular and extracellular environment. In particular, the maintenance of precise osmotic gradients of electrolytes is important. Such gradients affect and regulate the hydration of the body as well as blood pH, and are critical for nerve and muscle function. Both muscle tissue and neurons are considered electric tissues of the body. Muscles and neurons are activated by electrolyte activity between the extracellular fluid or interstitial fluid, and intracellular fluid. Electrolytes may enter or leave the cell membrane through specialized protein structures embedded in the plasma membrane called ion channels. For example, muscle contraction is dependent upon the presence of calcium (Ca2+), sodium (Na+), and potassium (K+). Without sufficient levels of these key electrolytes, muscle weakness or severe muscle contractions may occur.*
How long can I use C.G.P. continuously for?
C.G.P. (Creatine Glycerol Phosphate) is safe to use continuously per the directions.*
How much C.G.P. can I take per day? Is the dosage based on body weight?
The recommended dosage is 1 scoop on training days 30 to 40 minutes prior to working out or strenuous physical activity. C.G.P. can also be taken on "non”-training days to supersaturate the muscles with PCr (phospho-creatine). Dosage is not weight dependant. Higher dosages have been reported by users with higher physical exertion or body weight, but not higher than 30 grams (3 scoops) daily on training days.*