Improve Strength, Power, Performance, & Body-Composition
Full 40 Day Supply at a Cost Effective Price
Betaine Anhydrous has been taking the fitness industry by storm the last few months due to recent
studies showing increases in muscular endurance , body composition , and muscle growth
(hypertrophy)  within 6 weeks of continuous use.
Supplementing Betaine Anydrous may lead to:
- Increased Strength*
- Increased Lean Body Mass (Muscle Growth)*
- Decreased Body-fat Percentage *
- Increased Power Output *
A number of studies have shown that Betaine Anhydrous can increase strength and power in bouts of
exercise. A recent study in males who trained for 6 weeks showed that subjects who took two daily
doses of 1.25 grams of Betaine Anhydrous increased muscle mass by 4 lbs., decreased body-fat by 7%,
and increased arm size by 10% when compared to the placebo group. Results like this place Betaine
Anhydrous in the company of other proven ergogenic ingredients such as Creatine Monohydrate,
Arachidonic Acid (X-Gels), and Beta Alanine, all of which SNS currently produces. Each bottle of SNS
Betaine Anhydrous provides you with a full 40 day supply of this powerful ingredient at a very cost
Understanding this Awesome Ingredient!!:
For those of you who may not be interested in the science; this is a brief explanation to how Betaine
(TMG) works in promoting an increase in lean mass.
1) Methionine loses methyl group and Homocysteine is created.
2) Increased homocysteine levels impair insulin signalling and thus the mTOR pathway (which
increases protein synthesis) is impaired.
3) Glut4 may also be impaired due to reduced insulin signalling thus limiting glucose transportation
into a muscle cell.
4) Homocysteine can be recycled back into methionine if it gains a methyl group.
Trimethylgycine is Glycine with 3 methyl groups attached. It donates a methyl group to
homocysteine which is then recycled to make methionine.
5) Increase methionine levels also shown to increase nitrogen retention in pigs and thus signify an
increase in lean muscle.
Betaine (TMG) also acts as an osmolyte: it maintains cell volume in a similar way to Creatine.
To understand the science behind Betaine Anhydrous, it is first important to understand Homocysteine.
What is Homocysteine and what does it do?
Homocysteine (HCY) is an amino acid which is produced from methionine once methionine loses its
methyl group . Elevated levels of HCY has been shown to impair insulin signalling , which can in
turn reduce Akt (Protein kinase B) phosphorylation and thus impact protein synthesis .
Importance of the Akt (Protein Kinase B pathway (PKB))
PKB is able to induce protein synthesis via phosphatidylinositol 3-kinase (PI3K). PI3K activates PKB
which then activates mTOR [6, 7, 8]. This process is facilitated through a pathway known as PI3K/ AKT/
mTOR [6, 8]. mTOR is responsible for protein synthesis in humans and directly inhibits activation of cAMP
and catabolism .
Furthermore, as insulin signalling is impaired by elevated HCY levels, Glut4 (an insulin regulated glucose
transporter) will not be able to transport glucose into muscle cells, especially post exercise [9, 10].
The importance of Glut4 is recognised even more when examining diabetes patients who have
developed a resistance to insulin [9, 10]. When the body is unable to recognise insulin, Glut4 is not
activated and there is no longer an uptake of glucose into either muscle or fat cells [9, 10, 11]
It is because of this reason that hyperhomocysteinemia (elevated levels of HCY) has been linked to
insulin resistance .
Where does Betaine (Trimethylglycine) fit into all of this?
Trimethylglycine (TMG) is the amino acid Glycine with three methyl groups attached to it and it is
through these methyl groups where it serves a key function . Methionine can create Homocysteine
by losing its methyl group, however Homocysteine can also be converted back to Methionine upon
receiving a methyl group . TMG acts as this methyl donor and is thus able to reduce Homocysteine
levels through this process [13, 14] TMG is also able to increase levels of S-Adenosyl Methionine (a
universal methyl donating compound) which can then travel the body and donate methyl groups along
In pigs, increased levels of Methionine correlated to an increase in Nitrogen rentention. This indicates a
more positive nitrogen balance, lending to enhanced muscle growth .
Betaine (TMG) is also an osmolyte compound, meaning it plays a role in maintaining cell volume and
fluid balance in a similar manner to Creatine [12, 14]
Through reduction of Homocysteine levels, insulin signalling is improved and thus the anabolic pathways
are more readily activated. The end result of this process is improved body composition.
SNS Betaine Anhydrous can be stacked with SNS Creatine Monohydrate, Citrulline Malate, Leucine, X-
Gels and other SNS products for improved, synergistic results.
Serious Nutrition Solutions Baseline Series
Straight Forward, Top Quality, Cost Effective Sports Nutrition
Serving Size: 1 scoop
Servings Per Container: 100
Amount Per Serving:
Betaine Anydrous – 1 gram (1000 mg)
Other Ingredients: Magnesium Stearate
As a dietary supplement, tae 2.5 grams (2 and 1/2 scoops) 45 minutes to an hour prior to workout out or
take 1.5 grams (1.5 scoops) prior to working out and 1 scoop spaced approximately 8 hours before or
after. On non-workout days, take 1.5 grams (1 and 1/2 scoops) in the morning and 1 scoop in the evening.
Betaine Anhydrous can be taken with or without food.
This product is intended for healthy adults over 18 years of age. Consult a physician before using this or
any dietary supplement. This product should ot be used by women that are pregnant or nursing. Do not
use if you have any pre-existing medical condition or are taking any medication without consulting your
physician. Store in a cool, dry place. KEEP OUT OF REACH OF CHILDREN.